Skip to main content
Top
Published in: European Radiology 6/2006

01-06-2006 | Tips and Tricks

Transarterial chemoembolization in the treatment of hepatoblastoma in children

Authors: Thomas J. Vogl, Albert Scheller, Ursula Jakob, Stefan Zangos, Medhat Ahmed, Mohamed Nabil

Published in: European Radiology | Issue 6/2006

Login to get access

Abstract

Hepatoblastoma is one of the clinical challenges in children, as it is common and frequently unresectable. Chemotherapy can be administered regionally instead of systemically by transarterial chemoembolization (TACE) and thus improve prognosis. The advantages of this technique over systemic chemotherapy led to developing its role from being a palliative or an adjuvant preoperative treatment to being a potentially independent palliative or curative therapeutic option. The technical aspects and complications of a combined transarterial administration of chemotherapeutic and vascular occlusive agents in cases of hepatoblastoma in children are discussed, to give a comprehensive idea about the value of TACE in this context.
Literature
1.
go back to reference Ohtsuka Y, Matsunaga T, Yoshida H, Kouchi K, Okada T, Ohnuma N (2004) Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 34(2):127–133CrossRefPubMed Ohtsuka Y, Matsunaga T, Yoshida H, Kouchi K, Okada T, Ohnuma N (2004) Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 34(2):127–133CrossRefPubMed
2.
go back to reference Malogolowkin MH, Stanley P, Steele DA, Ortega JA (2000) Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 18(6):1279–1284PubMed Malogolowkin MH, Stanley P, Steele DA, Ortega JA (2000) Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 18(6):1279–1284PubMed
3.
go back to reference Tashjian DB, Moriarty KP, Courtney RA, Bean MS, Steele DA (2002) Preoperative chemoembolization for unresectable hepatoblastoma. Pediatr Surg Int 18(2–3):187–189CrossRefPubMed Tashjian DB, Moriarty KP, Courtney RA, Bean MS, Steele DA (2002) Preoperative chemoembolization for unresectable hepatoblastoma. Pediatr Surg Int 18(2–3):187–189CrossRefPubMed
4.
go back to reference Arcement CM, Towbin RB, Meza MP, Gerber DA, Kaye RD, Mazariegos GV, Carr BI, Reyes J (2000) Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 30(11):779–785CrossRefPubMed Arcement CM, Towbin RB, Meza MP, Gerber DA, Kaye RD, Mazariegos GV, Carr BI, Reyes J (2000) Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 30(11):779–785CrossRefPubMed
5.
go back to reference Latoo MY, Oliver A, Roebuck (2002) Anaesthetic management of hepatic artery chemoembolization in a paediatric patient. Paediatr Anaesth 12(7):629–631CrossRefPubMed Latoo MY, Oliver A, Roebuck (2002) Anaesthetic management of hepatic artery chemoembolization in a paediatric patient. Paediatr Anaesth 12(7):629–631CrossRefPubMed
7.
go back to reference Farhi DC, Odell CA, Shurin SB (1993) Myelodysplastic syndrome and acute myeloid leukemia after treatment for solid tumors of childhood. Am J Clin Pathol 100:270–275PubMed Farhi DC, Odell CA, Shurin SB (1993) Myelodysplastic syndrome and acute myeloid leukemia after treatment for solid tumors of childhood. Am J Clin Pathol 100:270–275PubMed
8.
go back to reference Moppet J, Oakhill A, Duncan AW (2001) Second malignancies in children: the usual suspects? Eur J Radiol 38:325–348 Moppet J, Oakhill A, Duncan AW (2001) Second malignancies in children: the usual suspects? Eur J Radiol 38:325–348
9.
go back to reference Van Thiel DH, Carr B, Iwatsuki S et al (1993) The 11-year Pittsburg experience with liver transplantation for hepatocellular carcinoma. J Surg Oncol Suppl 3:78–82PubMedCrossRef Van Thiel DH, Carr B, Iwatsuki S et al (1993) The 11-year Pittsburg experience with liver transplantation for hepatocellular carcinoma. J Surg Oncol Suppl 3:78–82PubMedCrossRef
10.
go back to reference Hu X, Li J, Jiang X, Chen Z (2004) Cure of hepatoblastoma with transcatheter arterial chemoembolization. J Ped Haematol/Oncol 26(1):60–63CrossRef Hu X, Li J, Jiang X, Chen Z (2004) Cure of hepatoblastoma with transcatheter arterial chemoembolization. J Ped Haematol/Oncol 26(1):60–63CrossRef
11.
go back to reference Yamaura K, Higashi M, Akiyoshi K, Itonaga Y, Inoue H, Takahashi S (2000) Pulmonary lipiodol embolism during transcatheter arterial chemoembolization for hepatoblastoma under general anesthesia. Eur J Anaesthesiol 17(11):704–708CrossRefPubMed Yamaura K, Higashi M, Akiyoshi K, Itonaga Y, Inoue H, Takahashi S (2000) Pulmonary lipiodol embolism during transcatheter arterial chemoembolization for hepatoblastoma under general anesthesia. Eur J Anaesthesiol 17(11):704–708CrossRefPubMed
12.
go back to reference Chou FI, Fang KC, Chung C, Lui WY, Chi CW, Liu RS, Chan WK (1995) Lipiodol uptake and retention by human hepatoma cells. Nucl Med Biol 22(3):379–386CrossRefPubMed Chou FI, Fang KC, Chung C, Lui WY, Chi CW, Liu RS, Chan WK (1995) Lipiodol uptake and retention by human hepatoma cells. Nucl Med Biol 22(3):379–386CrossRefPubMed
Metadata
Title
Transarterial chemoembolization in the treatment of hepatoblastoma in children
Authors
Thomas J. Vogl
Albert Scheller
Ursula Jakob
Stefan Zangos
Medhat Ahmed
Mohamed Nabil
Publication date
01-06-2006
Publisher
Springer-Verlag
Published in
European Radiology / Issue 6/2006
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-005-2827-5

Other articles of this Issue 6/2006

European Radiology 6/2006 Go to the issue