Skip to main content
Top
Published in: European Spine Journal 1/2015

01-01-2015 | Grand Rounds

Trans-oral approach for the management of a C2 neuroblastoma

Authors: K. M. I. Salem, J. Visser, N. A. Quraishi

Published in: European Spine Journal | Issue 1/2015

Login to get access

Abstract

Introduction

Neuroblastoma is the most common extra-cranial solid tumour in children. Metastasis in children to the upper cervical spine are quite rare.

Case report

An 8-year-old boy was referred to our service following a relapse of a right adrenal stage 4 neuroblastoma with a metastatic deposit in C2. This anterior tumour mass was pressing on the spinal cord with increasing pain in the base of skull, but without gross neurological deficit. He underwent urgent MRI and CT scans and then emergent surgery. The first stage was a posterior stabilization from occiput to C5 with a posterior decompression from C1 to C3 followed by a trans-oral approach to resect the main anterior tumour mass and reconstruction.

Conclusion

This is the first https://static-content.springer.com/image/art%3A10.1007%2Fs00586-014-3216-z/MediaObjects/586_2014_3216_Figa_HTML.jpg report of the use of a trans-oral approach to address a neuroblastoma lesion in the axial spine. This approach was used effectively to achieve local tumour clearance confirmed at 1-year follow-up. Pertinent information to the spinal surgeon on neuroblastoma and the use of the trans-oral approach to the axial spine are discussed.
Literature
1.
go back to reference Thiele CJ (1998) Neuroblastoma. In: Masters J (ed) Human cell culture. Kluwer Academic Publishers, Lancaster, pp 21–53 Thiele CJ (1998) Neuroblastoma. In: Masters J (ed) Human cell culture. Kluwer Academic Publishers, Lancaster, pp 21–53
2.
go back to reference Brodeur GM, Pritchard J, Berthold F, Carlsen NL, Castel V, Castelberry RP, De Bernardi B, Evans AE, Favrot M, Hedborg F et al (1993) Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 11(8):1466–1477PubMed Brodeur GM, Pritchard J, Berthold F, Carlsen NL, Castel V, Castelberry RP, De Bernardi B, Evans AE, Favrot M, Hedborg F et al (1993) Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 11(8):1466–1477PubMed
3.
go back to reference Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, Faldum A, Hero B, Iehara T, Machin D, Mosseri V, Simon T, Garaventa A, Castel V, Matthay KK (2009) The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 27(2):289–297PubMedCentralPubMedCrossRef Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, Faldum A, Hero B, Iehara T, Machin D, Mosseri V, Simon T, Garaventa A, Castel V, Matthay KK (2009) The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 27(2):289–297PubMedCentralPubMedCrossRef
4.
go back to reference Davenport KP, Blanco FC, Sandler AD (2012) Pediatric malignancies: neuroblastoma, Wilm’s tumor, hepatoblastoma, rhabdomyosarcoma, and sacroccygeal teratoma. Surg Clin North Am 92(3):745–767PubMedCrossRef Davenport KP, Blanco FC, Sandler AD (2012) Pediatric malignancies: neuroblastoma, Wilm’s tumor, hepatoblastoma, rhabdomyosarcoma, and sacroccygeal teratoma. Surg Clin North Am 92(3):745–767PubMedCrossRef
5.
go back to reference Naranjo A, Parisi MT, Shulkin BL, London WB, Matthay KK, Kreissman SG, Yanik GA (2011) Comparison of (1)(2)(3)I-metaiodobenzylguanidine (MIBG) and (1)(3)(1)I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children’s Oncology Group. Pediatr Blood Cancer 56(7):1041–1045PubMedCrossRef Naranjo A, Parisi MT, Shulkin BL, London WB, Matthay KK, Kreissman SG, Yanik GA (2011) Comparison of (1)(2)(3)I-metaiodobenzylguanidine (MIBG) and (1)(3)(1)I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children’s Oncology Group. Pediatr Blood Cancer 56(7):1041–1045PubMedCrossRef
6.
go back to reference Cheung KM, Mak KC, Luk KD (2012) Anterior approach to cervical spine. Spine (Phila Pa 1976) 37(5):E297–E302CrossRef Cheung KM, Mak KC, Luk KD (2012) Anterior approach to cervical spine. Spine (Phila Pa 1976) 37(5):E297–E302CrossRef
7.
go back to reference Winter RB, Lonstein J, Dennis F (1995) Anterior upper cervical procedures. In: Winter RB (ed) Atlas of Spine Surgery. WB Saunders, Philadelphia, pp 1–17 Winter RB, Lonstein J, Dennis F (1995) Anterior upper cervical procedures. In: Winter RB (ed) Atlas of Spine Surgery. WB Saunders, Philadelphia, pp 1–17
8.
go back to reference Crockard H (1994) Midline ventral approaches to the craniocervical junction and upper cervical spine. In: Sherk H (ed) The cervical spine: an atlas of cervical procedures. JB Lippincott Co., Philadelphia, pp 93–112 Crockard H (1994) Midline ventral approaches to the craniocervical junction and upper cervical spine. In: Sherk H (ed) The cervical spine: an atlas of cervical procedures. JB Lippincott Co., Philadelphia, pp 93–112
9.
go back to reference Fang HSY, Ong GB (1962) Direct anterior approach to the upper cervical spine. J Bone Joint Surg Am 44:1588–1604 Fang HSY, Ong GB (1962) Direct anterior approach to the upper cervical spine. J Bone Joint Surg Am 44:1588–1604
10.
go back to reference Henn JS, Lee MC, Rhoton ALJ (2006) Transoral approach to craniocervical junction and upper cervical spine. In: Kim DH, Henn JS, Vaccaro AR, Dickman CA (eds) Surgical anatomy and techniques to the spine. Saunders Elsevier, Philadelphia, pp 3–32 Henn JS, Lee MC, Rhoton ALJ (2006) Transoral approach to craniocervical junction and upper cervical spine. In: Kim DH, Henn JS, Vaccaro AR, Dickman CA (eds) Surgical anatomy and techniques to the spine. Saunders Elsevier, Philadelphia, pp 3–32
11.
go back to reference Menezes AH (1992) The anterior midline approach to the craniocervical region in children. Pediatr Neurosurg 18(5–6):272–281PubMedCrossRef Menezes AH (1992) The anterior midline approach to the craniocervical region in children. Pediatr Neurosurg 18(5–6):272–281PubMedCrossRef
12.
go back to reference Menezes AH, VanGilder JC (1988) Transoral-transpharyngeal approach to the anterior craniocervical junction. Ten-year experience with 72 patients. J Neurosurg 69(6):895–903PubMedCrossRef Menezes AH, VanGilder JC (1988) Transoral-transpharyngeal approach to the anterior craniocervical junction. Ten-year experience with 72 patients. J Neurosurg 69(6):895–903PubMedCrossRef
13.
go back to reference Tuite GF, Veres R, Crockard HA, Sell D (1996) Pediatric transoral surgery: indications, complications, and long-term outcome. J Neurosurg 84(4):573–583PubMedCrossRef Tuite GF, Veres R, Crockard HA, Sell D (1996) Pediatric transoral surgery: indications, complications, and long-term outcome. J Neurosurg 84(4):573–583PubMedCrossRef
Metadata
Title
Trans-oral approach for the management of a C2 neuroblastoma
Authors
K. M. I. Salem
J. Visser
N. A. Quraishi
Publication date
01-01-2015
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 1/2015
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-014-3216-z

Other articles of this Issue 1/2015

European Spine Journal 1/2015 Go to the issue