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Open Access 01-12-2014 | Meeting abstract

Trafficking of TNF via recycling endosomes in neutrophils

Authors: Nutan Srivastava, Paige Lacy

Published in: Allergy, Asthma & Clinical Immunology | Special Issue 2/2014

Excerpt

Neutrophils are highly abundant innate immune cells that contribute to asphyxic episodes of acute asthma exacerbations, and secrete the proinflammatory cytokine tumour necrosis factor-α (TNF). Recycling endosomes (REs) are specialized secretory compartments that perform multiple functions including trafficking of cytokines to cell surfaces, although these are not characterized in neutrophils. Our objective is to identify trafficking components in neutrophils that may contribute to cytokine secretion. …

Title: Trafficking of TNF via recycling endosomes in neutrophils
Authors: Nutan Srivastava
Paige Lacy
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Allergy, Asthma & Clinical Immunology / Issue Special Issue 2/2014
Electronic ISSN: 1710-1492
DOI: https://doi.org/10.1186/1710-1492-10-S2-A47

At a glance: The STEP trials

Springer Medicine

Trafficking of TNF via recycling endosomes in neutrophils

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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