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Critical Care
Published in: Critical Care 1/2018

Open Access 01-12-2018 | Letter

Gender differences in the use of atypical antipsychotic medications for ICU delirium

Authors: Kunal Karamchandani, Robert S. Schoaps, Jillian Printz, Jeffrey M. Kowaleski, Zyad J. Carr

Published in: Critical Care | Issue 1/2018

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Excerpt

Intensive care unit (ICU) delirium, an acute fluctuating disturbance of cognition associated with critical illness, is associated with increased mortality, ICU length of stay, mechanical ventilation, and hospital costs [1‐3]. Despite a link to increased long-term mortality, atypical antipsychotic medications (AAP) are frequently administered for the treatment of ICU delirium. Males have a higher risk of being diagnosed with ICU delirium (63% vs 36%) and being initiated on AAP (44% vs 40%) compared to females [4, 5]. …
Literature
1.
Ely EW, Gautam S, Margolin R, et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med. 2001;27(12):1892–900.CrossRef
2.
Ely EW, Shintani A, Truman B, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291(14):1753–62.CrossRef
3.
Milbrandt EB, Deppen S, Harrison PL, et al. Costs associated with delirium in mechanically ventilated patients. Crit Care Med. 2004;32(4):955–62.CrossRef
4.
Marshall J, Herzig SJ, Howell MD, et al. Antipsychotic utilization in the intensive care unit and in transitions of care. J Crit Care. 2016;33:119–24.CrossRef
5.
Aldemir M, Ozen S, Kara IH, Sir A, Bac B. Predisposing factors for delirium in the surgical intensive care unit. Crit Care. 2001;5(1):265–70.CrossRef
Metadata
Title
Gender differences in the use of atypical antipsychotic medications for ICU delirium
Authors
Kunal Karamchandani
Robert S. Schoaps
Jillian Printz
Jeffrey M. Kowaleski
Zyad J. Carr
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2018
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-018-2143-5

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