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Critical Care
Published in: Critical Care 2/2011

01-04-2011 | Letter

Early corticosteroid treatment for severe pneumonia caused by 2009 H1N1 influenza virus

Authors: Hong-Ryang Kil, Jae-Ho Lee, Kyung-Yil Lee, Jung-Woo Rhim, You-Sook Youn, Jin-Han Kang

Published in: Critical Care | Issue 2/2011

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Excerpt

A pandemic of the 2009 H1N1 influenza A virus infection occurred worldwide in 2009. Some previously healthy patients experienced rapidly progressive pneumonia leading to acute respiratory distress syndrome (ARDS) and even death. The effect of corticosteroids on these severely affected patients is controversial because of a lack of controlled clinical trials [1]. …
Literature
1.
2.
Lee KY, Rhim JW, Kang JH: Hyperactive immune cells (T cells) may be responsible for acute lung injury in influenza virus infections: a need for early immune-modulators for severe cases. Med Hypotheses 2011, 76: 64-69. 10.1016/j.mehy.2010.08.032CrossRefPubMed
3.
Quispe-Laime AM, Bracco JD, Barberio PA, Campagne CG, Rolfo VE, Umberger R, Meduri GU: H1N1 influenza A virus associated acute lung injury: response to combination oseltamivir and prolonged corticosteroid treatment. Intensive Care Med 2010, 36: 33-41. 10.1007/s00134-009-1727-6CrossRefPubMed
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Confalonieri M, Cifaldi R, Dreas L, Viviani M, Biolo M, Gabrielli M: Methylprednisolone infusion for life-threatening H1N1-virus infection. Ther Adv Respir Dis 2010, 4: 233-237. 10.1177/1753465810376951CrossRefPubMed
5.
Roberts C, Nirmalan M, O'Shea S: Steroid-sensitive post-viral inflammatory pneumonitis (PVIP). Am J Respir Crit Care Med 2010, 182: 1089-1090.CrossRefPubMed
Metadata
Title
Early corticosteroid treatment for severe pneumonia caused by 2009 H1N1 influenza virus
Authors
Hong-Ryang Kil
Jae-Ho Lee
Kyung-Yil Lee
Jung-Woo Rhim
You-Sook Youn
Jin-Han Kang
Publication date
01-04-2011
Publisher
BioMed Central
Published in
Critical Care / Issue 2/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc10082

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