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Head & Neck Oncology
Published in: Head & Neck Oncology 1/2011

Open Access 01-12-2011 | Case report

Temporal lobe necrosis: a dwindling entity in a patient with nasopharyngeal cancer after radiation therapy

Authors: Meera Dassarath, Zhongyuan Yin, Jing Chen, Hongli Liu, Kunyu Yang, Gang Wu

Published in: Head & Neck Oncology | Issue 1/2011

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Abstract

Introduction

Our objective was to report a case of misdiagnosed temporal lobe necrosis (TLN) in a patient with nasopharyngeal cancer (NPC) after radiation therapy.

Case Presentation

We report a case of a 45 years old Chinese woman who developed moderate to severe headache and dizziness 1 year after 2D radiation therapy for NPC. Subsequent MRI scanning revealed a big enhancing mass in the right temporal lobe. The initial diagnosis was metastatic or intracranial extension of NPC, or a primary intracranial malignancy. She was referred to the neurosurgery department where a maximal surgical resection of the lesion was performed. A diagnosis of TLN was made according to the final histology.

Conclusion

TLN still matters in the IMRT era. The diagnostic quagmire of TLN lies in its close resemblance to neoplasm on clinical presentation and imaging. Reviewing the patient's treatment plan to scrutinize the dose to the temporal lobes is an important prerequisite for diagnosis.
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Metadata
Title
Temporal lobe necrosis: a dwindling entity in a patient with nasopharyngeal cancer after radiation therapy
Authors
Meera Dassarath
Zhongyuan Yin
Jing Chen
Hongli Liu
Kunyu Yang
Gang Wu
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Head & Neck Oncology / Issue 1/2011
Electronic ISSN: 1758-3284
DOI
https://doi.org/10.1186/1758-3284-3-8

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