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Malaria Journal
Published in: Malaria Journal 1/2014

Open Access 01-12-2014 | Opinion

Towards rapid genotyping of resistant malaria parasites: could loop-mediated isothermal amplification be the solution?

Author: Rashad Abdul-Ghani

Published in: Malaria Journal | Issue 1/2014

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Abstract

Loop-mediated isothermal amplification (LAMP) is an innovative molecular technique that has been validated for point-of-care testing to diagnose malaria. Molecular detection and tracking of anti-malarial drug resistance is mainly based on highly sophisticated, costly and time-consuming techniques. With the validation of resistance-associated gene mutations in malaria parasites, there is a need to develop rapid, easy-to-use molecular tests for anti-malarial drug resistance genotyping. LAMP could be further developed as a point-of-care test to rapidly detect anti-malarial drug resistance-associated molecular markers, thereby help detecting and monitoring drug resistance in surveillance studies.
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Metadata
Title
Towards rapid genotyping of resistant malaria parasites: could loop-mediated isothermal amplification be the solution?
Author
Rashad Abdul-Ghani
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2014
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-13-237

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