Published in:
01-03-2012 | Case Report
Topical application of autologous adipose-derived mesenchymal stem cells (MSCs) for persistent sterile corneal epithelial defect
Authors:
George I. Agorogiannis, Vassilia-Ismini Alexaki, Ourania Castana, George D. Kymionis
Published in:
Graefe's Archive for Clinical and Experimental Ophthalmology
|
Issue 3/2012
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Excerpt
Different causes of corneal persistent epithelial defects (PED) have been described including dry eye, corneal epithelial stem cell deficiency, diabetes mellitus, and neurotrophic keratopathy (after herpetic keratitis or corneal surgery). Corneal PEDs could lead to a cascade of events throughout the cornea, resulting in stromal degradation, thinning and in advanced cases, corneal perforation. …