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7548 search results for:

Perinatal Injury 

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  1. 13-07-2023 | Perinatal Asphyxia | OriginalPaper

    Predictive ability of 2-h serum neutrophil gelatinase-associated lipocalin for perinatal asphyxia-induced acute kidney injury

    In Nigeria, diagnosing or predicting acute kidney injury (AKI) early with the current biomarkers in newborns with perinatal asphyxia is challenging, especially when perinatal asphyxia identification is solely dependent on Apgar scores. The gold …

  2. Open Access 29-04-2023 | OriginalPaper

    The impact of perinatal brain injury on retinal nerve fiber layer thickness and optic nerve head parameters of premature children

  3. 01-01-2022 | Acute Kidney Injury | OriginalPaper

    Urinary beta-2 microglobulin as an early predictive biomarker of acute kidney injury in neonates with perinatal asphyxia

    To evaluate the role of urinary beta-2 microglobulin (B2mG) as an early predictive biomarker of acute kidney injury (AKI) in neonates with perinatal asphyxia. In this prospective cohort study, 80 term infants with perinatal asphyxia were included.

  4. 01-12-2021 | Cytokines | Original Research

    Sustained peripheral immune hyper-reactivity (SPIHR): an enduring biomarker of altered inflammatory responses in adult rats after perinatal brain injury

    Globally, prematurity is a major cause of infant mortality and long-term disability in children [ 1 , 2 ]. Preterm birth is a principal cause of neonatal morbidity and mortality, accounting for 70% of neonatal deaths [ 3 ]. As perinatal care has …

  5. Open Access 01-12-2023 | Magnetic Resonance Imaging | OriginalPaper

    Radiomics based of deep medullary veins on susceptibility-weighted imaging in infants: predicting the severity of brain injury of neonates with perinatal asphyxia

    A patient with hypoxic-ischemic encephalopathy (HIE) may suffer from neurological problems as a result of neonatal asphyxia [ 1 ]. Globally, it causes 1 to 8 neonatal deaths per 1000 live births, making it one of the leading causes of neonatal …

  6. 18-05-2022 | Epilepsy

    Hemiconvulsion Hemiplegia Epilepsy (HHE) Syndrome after Perinatal Hypoxic–Ischemic Injury

  7. 01-08-2011 | ReviewPaper

    Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury

    Perinatal hypoxia-ischemia remains the single most important cause of brain injury in the newborn, leading to death or lifelong sequelae. Because of the fact that there is still no specific treatment for perinatal brain lesions due to the …

  8. 01-05-2014 | OriginalPaper

    White Matter Injury Induced by Perinatal Exposure to Glutaric Acid

    Glutaric acid (GA) is a neurotoxic metabolite that accumulates in the CNS of patients with glutaric acidemia-I (GA-I), a neurometabolic disease caused by deficient activity of glutaryl-CoA dehydrogenase. Most GA-I patients display characteristic …

  9. Open Access 01-12-2018 | OriginalPaper

    Effects of umbilical cord blood cells, and subtypes, to reduce neuroinflammation following perinatal hypoxic-ischemic brain injury

    Exposure to severe acute or prolonged hypoxia-ischemia (HI) during the highly vulnerable perinatal period is a principal contributor to neuropathology and life-long neurological deficits, such as cerebral palsy. A number of studies, using both …

  10. 01-10-2018 | ReviewPaper

    Neutrophil gelatinase-associated lipocalin as predictor of acute kidney injury in neonates with perinatal asphyxia: a systematic review and meta-analysis

    There is growing evidence that neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of acute kidney injury. The objective of this meta-analysis is to determine the accuracy of serum and urinary NGAL in the detection of acute …

  11. 01-09-2017 | OriginalPaper

    Maternal pseudo-Bartter syndrome associated with severe perinatal brain injury

  12. 01-12-2016 | OriginalPaper

    Predicting Severity of Acute Kidney Injury in Term Neonates with Perinatal Asphyxia Using Urinary Neutrophil Gelatinase Associated Lipocalin

    Renal injury is the most common organ dysfunction in perinatal asphyxia occurring in 40–50 % cases [ 1 ]. If Acute Kidney Injury (AKI) is not recognized early in neonates with perinatal asphyxia, the mortality is likely to increase. AKI diagnosis …

  13. 01-10-2016 | OriginalPaper

    Perinatal Brain Injury is Accompanied by Disturbances in Expression of SLC Protein Superfamily in Endotheliocytes of Hippocampal Microvessels

    The peculiarities in expression of transport proteins and the proteins implicated in the control of glycolysis by the cellular components of neurovascular units were examined in animals of different age under normal conditions and after modeled …

  14. 01-06-2010 | ReviewPaper

    MRI of perinatal brain injury

    MRI is invaluable in assessing the neonatal brain following suspected perinatal injury. Good quality imaging requires adaptations to both the hardware and the sequences used for adults or older children. The perinatal and postnatal details often …

  15. 01-10-2001 | Abstract

    Brain development after perinatal cerebral white matter injury

  16. Open Access 01-02-2014 | OriginalPaper

    Na+/H+ Exchangers and Intracellular pH in Perinatal Brain Injury

    Encephalopathy consequent on perinatal hypoxia–ischemia occurs in 1–3 per 1,000 term births in the UK and frequently leads to serious and tragic consequences that devastate lives and families, with huge financial burdens for society. Although the …

  17. 01-04-2001 | OriginalPaper

    Perinatal asphyxia: Timing and mechanisms of injury in neonatal encephalopathy

    This article summarizes the recent medical literature regarding perinatal asphyxia with respect to timing and mechanisms of injury for neonates who were clinically diagnosed with an encephalopathy in the newborn period. Multiple mechanisms of …

  18. 01-08-2001 | OriginalPaper

    Renal injury in perinatal hypoxia: ultrasonography and changes in renal function

     We studied 12 hypoxaemic neonates (5 mature newborns, birth weight 2850–4200 g, gestational age 37–41 weeks; and 7 premature newborns, birth weight 770–1850 g, gestational age 27–34 weeks;) with repeated urine and blood chemistry on the 1st and …

  19. 01-07-2006 | ReviewPaper

    Magnetic resonance imaging in perinatal brain injury: clinical presentation, lesions and outcome

    Neonatal MR imaging is invaluable in assessing the term born neonate who presents with an encephalopathy. Successful imaging requires adaptations to both the hardware and the sequences used for adults. The perinatal and postnatal details often …

  20. 01-01-2002 | OriginalPaper

    Caspase-3 activation and caspase-like proteolytic activity in human perinatal hypoxic-ischemic brain injury

    Human perinatal hypoxic-ischemic brain injury is an important cause of death and morbidity. One relatively common pattern of perinatal injury involves selective neuronal death in the ventral gray matter of the pons and in the subiculum of the …

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