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Legg-Calvé-Perthes Disease 

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  1. Open Access 01-12-2024 | OriginalPaper

    Prediction of the active compounds and mechanism of Biochanin A in the treatment of Legg-Calvé-Perthes disease based on network pharmacology and molecular docking

    Legg-Calve-Perthes disease (LCPD) is among the major teratological and disabling diseases of the hip in children. It typically occurs in children aged 4–8 years old (mean, 6.5 years old) [ 1 ]. Genetic factors combined with environmental ones …

  2. 17-03-2023 | Osteoarthrosis | OriginalPaper

    Incidence of total hip arthroplasty in patients with Legg-Calve-Perthes disease after conservative or surgical treatment: a meta-analysis

    Legg-Calve-Perthes disease (LCPD) is a self-limiting condition characterized by avascular necrosis of the femoral epiphysis, with a worldwide prevalence of 5.1–16.9 per 100,000 individuals [ 1 – 3 ]. Treatment options vary depending on the age of …

  3. Open Access 01-12-2021 | Obesity | OriginalPaper

    High blood pressure and overweight in children with Legg-Calvé-Perthes disease: a nationwide population-based cohort study

    The etiology of Legg-Calvé-Perthes disease (LCPD) remains cloudy but a vascular component in the development of this condition, possibly in combination with mechanical stress, has been suggested [ 1 ] amongst other numerous hypotheses [ 2 ]. The …

  4. 18-06-2022 | Arthrography | OriginalPaper

    Does transepiphyseal drilling and closure of the greater trochanter in early Legg-Calve-Perthes disease improve natural history?

    Legg-Calve-Perthes disease (LCPD) is a true orthopedic enigma. There is no consensus regarding the etiology of the disease and even more disagreement about the treatment strategy. The core problem is abrupt disruption of the vascular supply to the …

  5. 29-09-2022 | OriginalPaper

    Predictors of radiographic outcomes of conservative and surgical treatment of Legg-Calvé-Perthes disease

    Legg-Calvé-Perthes disease (LCPD) is a paediatric hip condition caused by a period of vascular occlusion of femoral neck vessels resulting in avascular necrosis of the proximal femoral epiphysis potentially leading to a collapse of femoral head …

  6. Open Access 01-12-2020 | McCune-Albright syndrome | OriginalPaper

    Legg-Calve-Perthes disease in an 8-year old girl with Acrodysostosis type 1 on growth hormone therapy: case report

    Acrodysostosis (ACRDYS) is a rare skeletal dysplasia with skeletal abnormalities and multi-hormonal resistance similar to PHP1A, but caused by mutations downstream of the genes involved in PHP1A. Whereas PHP1A results from mutations of the gene …

  7. 01-06-2022 | Erratum

    Correction to: Comparative effectiveness of treatment modalities in severe Legg-Calvé-Perthes disease: Systematic review and network meta-analysis of observational studies

  8. Open Access 01-12-2020 | OriginalPaper

    Range of abduction in patients with Legg-Calvé-Perthes disease – a nationwide register-based cohort study

    Early symptoms of Legg-Calvé-Perthes Disease (LCPD) can initially be discrete and the clinical presentation may vary. However, pain and a decrease in range of motion of the hip, especially in abduction and rotation, are relatively common [ 15 ].

  9. 13-09-2023 | Erratum

    Correction to: The quality of online information on LeggCalvéPerthes disease: can we do better?

  10. Open Access 18-02-2023 | Hip-TEP | OriginalPaper

    Total hip arthroplasty through the direct anterior approach for sequelae of LeggCalvéPerthes disease

    LeggCalvéPerthes disease (LCPD) is characterized by osteonecrosis of the proximal femoral epiphysis during childhood caused by idiopathic disruption of blood flow to the femoral head [ 1 – 3 ]. While in some cases the osteonecrosis can resolve …

  11. 06-07-2023 | OriginalPaper

    The quality of online information on LeggCalvéPerthes disease: can we do better?

    By 2018, over 312 million individuals in the USA had access to the Internet [ 1 ]. Many of these individuals frequently access health information when online [ 2 , 3 ]. Yet, while 52% of users feel that the material contained on these …

  12. Open Access 01-12-2017 | OriginalPaper

    Monobloc implants in cementless total hip arthroplasty in patients with Legg-Calve-Perthes disease: a long-term follow-up

    Legg-Calve-Perthes disease(LCPD) is characterized by osteonecrosis of the femoral head during childhood [ 1 , 2 ]. Similar to other childhood hip disorders, LCPD has the development of degenerative coxarthrosis as its natural history [ 3 ]. Total …

  13. Open Access 01-12-2015 | OriginalPaper

    Comparative study of serum proteomes in Legg-Calve-Perthes disease

    Legg-Calve-Perthes disease (LCPD) is an idiopathic osteonecrosis of the developing femoral head complicated by pain and disability of the hip joint. The disease affects childhood between 6 and 9 years of age. The estimated annual incidence ranges …

  14. 01-01-2016 | OriginalPaper

    Triple osteotomy of the pelvis for Legg-Calve-Perthes disease: a mean fifteen year follow-up

    The aim of the treatment of Legg-Calve-Perthes disease (LCPD) is to prevent hip osteoarthritis [ 1 ]. Many treatments have been described in order to prevent or limit femoral head deformation by containing the head within the acetabulum, using it …

  15. 01-01-1997 | OriginalPaper

    The treatment of Legg-Calvé-Perthes disease

    To contain or not to contain

    In order to evaluate a treatment protocol involving a non-containment method and femoral osteotomy when lateral subluxation of the femoral head develops, 39 children with 42 affected hips were examined radiologically an average of 7 years …

  16. 01-11-1997 | OriginalPaper

    Transtrochanteric rotational osteotomy for Legg-Calvé-Perthes disease

    A retrospective review identified 20 hips in 19 children with Legg-Calvé-Perthes disease (Perthes' disease) who underwent transtrochanteric rotational osteotomy. Indications depend on patient age and the radiographic appearances. This procedure is …

  17. 01-03-2015 | OriginalPaper

    Tönnis triple pelvic osteotomy for Legg-Calve-Perthes disease

    Over 100 years have passed since the first introduction of Legg-Calve-Perthes Disease (LCP) but there is still a controversy about the aetiology and treatment of the disease. LCP disease is a pediatric form of femoral head avascular necrosis that …

  18. 01-07-2006 | OriginalPaper

    Multicenter study for Legg-Calvé-Perthes disease in Japan

  19. 01-12-2013 | OriginalPaper

    Legg-Calvé-Perthes disease: role of isolated adductor tenotomy?

    Legg-Calve-Perthes disease (LCPD) is a self-limiting condition of the immature hip characterized by aseptic necrosis of the femoral head, followed by a subchondral fracture, fragmentation, revascularization, and remodeling [ 1 – 4 ]. The condition …

  20. 01-01-2009 | Report

    Case Reports: Legg-Calvé-Perthes Disease in Czech Archaeological Material

    Legg-Calvé-Perthes disease (osteochondrosis of the femoral head) has been recognized in archaeological material for nearly a century but is extremely rare. We describe two Czech cases from archaeological findings. The first case was diagnosed in …

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