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410 search results for:

Darifenacin 

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  1. 01-01-2023 | Renal Ultrasonography | News

    Darifenacin

    Acute kidney injury and constipation following drug overdose and misuse: case report
  2. 01-11-2019 | Endoscopy | News

    Darifenacin

    First report of oesophagitis: case report
  3. 01-09-2021 | Overactive Bladder | OriginalPaper

    Effect of darifenacin on fecal incontinence in women with double incontinence

    Urgency urinary incontinence (UUI) and fecal incontinence are two highly prevalent pelvic floor disorders, which negatively impact quality of life. Among women with UUI symptoms, up to 20% may also have fecal incontinence symptoms [ 1 – 4 ], termed …

  4. 01-09-2021 | Overactive Bladder | Letter

    Commentary: effect of darifenacin on fecal incontinence in women with double incontinence

  5. 01-03-2009 | Abstract

    Darifenacin

    First report of interstitial granulomatous dermatitis: case report
  6. 01-09-2004 | Abstract

    Darifenacin: less adverse effects than oxybutynin

  7. 01-11-2004 | OriginalPaper

    Darifenacin

    A Viewpoint by Francois Haab
  8. 01-11-2004 | OriginalPaper

    Darifenacin

    A Viewpoint by Rodney A. Appell
  9. 01-11-2004 | OriginalPaper

    Darifenacin

    In the Treatment of Overactive Bladder

    Darifenacin is a selective muscarinic M3-receptor antagonist that has been evaluated in clinical trials in patients with overactive bladder syndrome (OAB) using a controlled-release formulation.▴ In multicentre, randomised, double-blind trials …

  10. 01-11-2004 | OriginalPaper

    Darifenacin

    A Viewpoint by Scott Serels
  11. 01-04-2006 | ReviewPaper

    The Clinical Pharmacokinetics of Darifenacin

    Darifenacin hydrobromide is a selective muscarinic M3 receptor antagonist that is indicated for use in treatment of overactive bladder disorder. Darifenacin was found to have a short terminal elimination half-life after intravenous and …

  12. 01-10-2015 | ReviewPaper

    Treatment of Overactive Bladder in the Elderly Female: The Case for Trospium, Oxybutynin, Fesoterodine and Darifenacin

    Overactive bladder (OAB) is a common constellation of lower urinary tract storage symptoms that causes a significant impact on a person’s quality of life. The elderly may be disproportionally impacted by these symptoms due to concomitant poor …

  13. 01-12-2011 | OriginalPaper

    Time-to-effect with darifenacin in overactive bladder: a pooled analysis

    The chronic condition overactive bladder (OAB) comprises bothersome symptoms such as urinary urgency, incontinence episodes (IEs), and frequency of micturition [ 1 , 2 ], which can be associated with a detrimental effect on patients’ health-related …

  14. 01-06-2008 | OriginalPaper

    The effect of Darifenacin on overactive bladders in female and male rabbits

    Our current study utilized a model of bladder instability to compare the effectiveness of darifenacin, a selective m3 muscarinic antagonist, at inhibiting overactive bladder (OAB) dysfunction in both male and female rabbits. Twenty-four male and …

  15. 01-09-2004 | BriefCommunication

    Darifenacin is an effective and well-tolerated once-daily treatment for overactive bladder

  16. 01-10-2008 | OriginalPaper

    Human urine with solifenacin intake but not tolterodine or darifenacin intake blocks detrusor overactivity

    The objective of the study was to evaluate the local effects of three antimuscarinics excreted into human urine after oral ingestion. Two normal adult collected their voided urine after taking oral doses of tolterodine, darifenacin, and …

  17. 01-09-2004 | OriginalPaper

    Preview of new drugs for overactive bladder and incontinence: Darifenacin, solifenacin, trospium, and duloxetine

    This year, the US Food and Drug Administration will approve four new drugs indicated for the treatment of lower urinary tract dysfunction. Darifenacin, solifenacin, and trospium are antimuscarinic agents aimed at relieving the symptoms of …

  18. 01-05-2006 | OriginalPaper

    Dose response with darifenacin, a novel once-daily M3 selective receptor antagonist for the treatment of overactive bladder: results of a fixed dose study

    This study evaluated the efficacy, tolerability, and safety of darifenacin, an M3 selective receptor antagonist (M3 SRA), in patients with overactive bladder (OAB). In a multicenter, double-blind, placebo-controlled dose-ranging study, 439 adult …

  19. 01-09-2005 | OriginalPaper

    Efficacy and tolerability of darifenacin, a muscarinic M3 selective receptor antagonist (M3 SRA), compared with oxybutynin in the treatment of patients with overactive bladder

    A randomized, double-blind, placebo-controlled, four-way crossover, safety study of darifenacin versus oxybutynin was carried out on 76 patients with overactive bladder (OAB). Adults with OAB received 2 weeks each of darifenacin 15 and 30 mg once …

  20. 01-08-2019 | Acute Kidney Injury | News

    Amiodarone/apixaban/darifenacin interaction

    Bruising following drug interaction and GI bleeding: case report

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