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31 search results for:

Acylureido Penicillin 

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  1. Open Access 01-11-2020 | Acute Myeloid Leukemia | OriginalPaper

    Use of carbapenems and glycopeptides increases risk for Clostridioides difficile infections in acute myeloid leukemia patients undergoing intensive induction chemotherapy

    Patients with acute myeloid leukemia (AML) are often exposed to broad-spectrum antibiotics and thus at high risk of Clostridioides difficile infections (CDI). As bacterial infections are a common cause for treatment-related mortality in these …

  2. Open Access 01-12-2022 | Premature Rupture of Membranes | OriginalPaper

    Impact of early antibiotic exposure on the risk of colonization with potential pathogens in very preterm infants: a retrospective cohort analysis

    Infections are a major cause of morbidity and mortality in preterm infants [ 1 ]. The latter have an increased vulnerability to infections because of an immaturity of their mucosal barriers and alterations in their immune responses compared to …

  3. Open Access 01-12-2020 | Antibiotic | OriginalPaper

    Use of microbiological and patient data for choice of empirical antibiotic therapy in acute cholangitis

    Acute cholangitis is a potentially life-threatening infection of the biliary tract. The main underlying pathological process is obstruction of bile ducts leading to cholestasis and impeded clearance of intestinal microorganisms ascending from the …

  4. 01-10-2019 | Antibiotic | OriginalPaper

    Influence of primary care antibiotic prescribing on incidence rates of multidrug-resistant Gram-negative bacteria in hospitalised patients

    Klebsiella pneumoniae and Escherichia coli represent the two main extended-spectrum β-lactamase (ESBL)-producing bacteria; they are listed as multidrug-resistant Gram-negative (MRGN) bacteria for which new treatment regimens are urgently required [ …1

  5. Open Access 01-12-2019 | Acute Pancreatitis | ReviewPaper

    2019 WSES guidelines for the management of severe acute pancreatitis

    Although most patients with acute pancreatitis have the mild form of the disease, about 20–30% develops a severe form, often associated with single or multiple organ dysfunction requiring intensive care. Identifying the severe form early is one of …

  6. 01-05-2019 | OriginalPaper

    Perioperative antibiotic prophylaxis in renal transplantation: a single-center comparison between two regimens and a brief survey among the Eurotransplant renal transplantation centers

    Administration of perioperative antibiotic prophylaxis (PAP) to prevent surgical site infections (SSI) complements renal transplantation. In 1988, Cohen et al. [ 1 ] showed that PAP with three doses of cefuroxime and piperacillin significantly …

  7. 01-07-1997 | ReviewPaper

    Drug Administration in Chronic Liver Disease

    Cirrhosis encompasses a range of pathophysiological changes that may alter drug disposition. Drugs that are dependent primarily on the liver for their systemic clearance are more likely to be subject to reduced elimination and subsequent …

  8. 01-11-1998 | OriginalPaper

    Acute Pancreatitis

    An Overview of Emerging Pharmacotherapy

    Biotechnology has enabled greater understanding of the cellular and molecular biology of acute pancreatitis and has offered the possibility of a new generation of biodrugs to treat this disease. The proteases inhibitor gabexate mesilate has proven …

  9. 01-11-2001 | OriginalPaper

    Piperacillin/Tazobactam

    A Pharmacoeconomic Review of its Use in Moderate to Severe Bacterial Infections
  10. 01-08-1997 | Abstract

    Preventing ADRs in patients with liver disease

  11. 01-05-2002 | OriginalPaper

    Acute pancreatitis; target intensive therapy to those most likely to have a severe attack

  12. Open Access 01-12-2017 | ReviewPaper

    Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations

    Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society …

  13. Open Access 01-12-2017 | OriginalPaper

    Colonization of long term care facility patients with MDR-Gram-negatives during an Acinetobacter baumannii outbreak

    Long term care facilities (LTCF) play an essential role in contemporary healthcare systems due to an ageing population in the industrialized world. There is increasing evidence suggesting that residents in LTCFs are frequently colonized by …

  14. Open Access 01-12-2016 | OriginalPaper

    Prolonged outbreak of clonal MDR Pseudomonas aeruginosa on an intensive care unit: contaminated sinks and contamination of ultra-filtrate bags as possible route of transmission?

    Multidrug-resistant (MDR) P. aeruginosa are among the most commonly-found organisms which cause nosocomial infections in intensive care units [ 12 , 13 , 18 , 21 ]. They are associated with increased mortality as well as increased hospital costs [ …

  15. Open Access 01-12-2016 | OriginalPaper

    Epidemiology of multidrug resistant bacterial organisms and Clostridium difficile in German hospitals in 2014: Results from a nationwide one-day point prevalence of 329 German hospitals

    Antibiotic resistance of bacterial pathogens is an emerging problem worldwide [ 1 ]. While no longer limited to in-patient care, hospitals are still a focal point for transmissions and infections with multidrug resistant organisms (MDRO). While for …

  16. Open Access 01-12-2015 | OriginalPaper

    Improving hospital hygiene to reduce the impact of multidrug-resistant organisms in health care–a prospective controlled multicenter study

    Nosocomial infections are the most common complication that can occur during inpatient hospital care [ 1 ], and antimicrobial resistance is a serious threat to public health [ 2 ]. The Second European Point Prevalence Survey 2011–2012, involving 30 …

  17. Open Access 01-12-2015 | Abstract

    More than half of ESBL-E are susceptible to fluoroquinolones: admission prevalence data from eight non-ICUs in a German university hospital

    Little information is available on prevalence of extended-spectrum-betalactamase-producing Enterobacteriaceae (ESBL-E) with and without additional resistance to fluoroquinolones. In Germany, Enterobacteriaceae are classified according to their …

  18. 01-04-2015 | OriginalPaper

    Prevalence of carbapenem-resistant organisms and other Gram-negative MDRO in German ICUs: first results from the national nosocomial infection surveillance system (KISS)

    According to the WHO’s global report on surveillance of antimicrobial resistance issued April 2014, the world is on the verge of entering a post-antibiotic era. However, the exact magnitude of the problem at both population and global levels is …

  19. 01-11-1999 | OriginalPaper

    Immunoglobulins for Prophylaxis and Treatment of Sepsis: New Experience with a Natural Immunomodulatory Compound

  20. 01-11-1999 | OriginalPaper

    Prophylactic Use of Immunoglobulins in Cardiac Surgery

    Cardiopulmonary bypass is associated with an injury that may cause pathophysiological changes in form of systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), and mediator induced multi organ failure (MIMOV).

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