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European Archives of Paediatric Dentistry

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01-08-2019 | Tooth Extraction | Original Scientific Article

Effectiveness of topical haemocoagulase as a haemostatic agent in children undergoing extraction of primary teeth: a split-mouth, randomised, double-blind, clinical trial

Authors: D. F. Swamy, E. S. Barretto, J. S. L. Rodrigues

Published in: European Archives of Paediatric Dentistry | Issue 4/2019

Abstract

Aim

To assess the effectiveness of topically-administered haemocoagulase (batroxobin) (HC) following dental extractions in children.

Design

Split-mouth design, where either HC (test) or Normal Saline (control) (NS) was administered to children (5–9 years) requiring bilateral extractions of primary molars. Participants were randomised to (i) extraction sequence; (ii) test-solution administered thereafter. Outcome measure: time taken (in seconds) for complete cessation of bleeding.

Results

Thirty participants completed the trial receiving HS (n = 30) and NS (n = 30). No adverse events were reported. Time to bleeding cessation was lower in HS group (82.5 ± 13.99 s) than NS group (240.5 ± 54.34 s). Difference between groups (paired t test) was statistically very highly significant (P = 0.000).

Conclusion

Topical HC produced significant reductions in time for haemostasis and was clinically effective in controlling haemorrhage from extraction wounds in children. HC may be favourably utilised by paediatric dentists, especially with pre-cooperative or special-healthcare-needs patients, improving patient care.

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Title: Effectiveness of topical haemocoagulase as a haemostatic agent in children undergoing extraction of primary teeth: a split-mouth, randomised, double-blind, clinical trial
Authors: D. F. Swamy
E. S. Barretto
J. S. L. Rodrigues
Publication date: 01-08-2019
Publisher: Springer Berlin Heidelberg
Keywords: Tooth Extraction
Tooth Extraction
Published in: European Archives of Paediatric Dentistry / Issue 4/2019
Print ISSN: 1818-6300
Electronic ISSN: 1996-9805
DOI: https://doi.org/10.1007/s40368-018-0406-0

2024 ASCO Annual Meeting

Springer Medicine

Effectiveness of topical haemocoagulase as a haemostatic agent in children undergoing extraction of primary teeth: a split-mouth, randomised, double-blind, clinical trial

Abstract

Aim

Design

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Aim

Design

Results

Conclusion

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