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Head & Neck Oncology
Published in: Head & Neck Oncology 1/2012

Open Access 01-12-2012 | Case report

Tongue cancer in young patients: case report of a 26-year-old patient

Authors: Aleksandra Credé, Michael Locher, Marius Bredell

Published in: Head & Neck Oncology | Issue 1/2012

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Abstract

Introduction

This article presents the case of a 26-year-old woman with tongue cancer. The median age at the diagnosis of the tongue’s cancer is 61 years. Only approximately 2% of patients are diagnosed before the age of 35.

Case presentation

Our patient survived acute myeloid leukemia (AML) before her second year. She had been having recurrent, poorly healing aphtae on the right side of the tongue for a period of months before the symptoms of the tongue cancer appeared. As a treatment a partial glossectomy was conducted on the right side and a neck dissection of levels I-III. Than a reconstruction of the tongue with a radialis free vascularised flap from left side was performed.

Discussion

It should be always looked for the causal factor in young patients with a neoplasm. There is strong evidence for second malignant neoplasms in survivors of childhood cancer.
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Literature
1.
Curado MP, Hashibe M: Recent changes in the epidemiology of head and neck cancer. Curr Opin Oncol. 2009, 21: 194-200. 10.1097/CCO.0b013e32832a68ca.CrossRefPubMed
2.
Shiboski CH, Schmidt BL, Jordan RC: Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20–44 years. Cancer. 2005, 103: 1843-1849. 10.1002/cncr.20998.CrossRefPubMed
3.
Toner M, O'Regan EM: Head and neck squamous cell carcinoma in the young: a spectrum or a distinct group? Part 1. Head Neck Pathol. 2009, 3: 246-248. 10.1007/s12105-009-0135-0.PubMedCentralCrossRefPubMed
4.
Soudry E, Preis M, Hod R, Hamzany Y, Hadar T, Bahar G, Strenov Y, Shpitzer T: Squamous cell carcinoma of the oral tongue in patients younger than 30 years: clinicopathologic features and outcome. Clin Otolaryngol. 2010, 35: 307-312. 10.1111/j.1749-4486.2010.02164.x.CrossRefPubMed
5.
Byers RM: Squamous cell carcinoma of the oral tongue in patients less than thirty years of age. Am J Surg. 1975, 130: 475-478. 10.1016/0002-9610(75)90487-0.CrossRefPubMed
6.
Newman AN, Rice DH, Ossoff RH, Sisson GA: Carcinoma of the tongue in persons younger than 30 years of age. Arch Otolaryngol. 1983, 109: 302-304. 10.1001/archotol.1983.00800190024006.CrossRefPubMed
7.
Serefoglou Z, Yapijakis C, Nkenke E, Vairaktaris E: Genetic association of cytokine DNA polymorphisms with head and neck cancer. Oral Oncol. 2008, 44: 1093-1099. 10.1016/j.oraloncology.2008.02.012.CrossRefPubMed
8.
Báez A: Genetic and environmental factors in head and neck cancer genesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008, 26: 174-200. 10.1080/10590500802129431.CrossRefPubMed
9.
Duffey DC, Eversole LR, Abemayor E: Oral lichen planus and its association with squamous cell carcinoma: an update on pathogenesis and treatment implications. Laryngoscope. 1996, 106: 357-362. 10.1097/00005537-199603000-00022.CrossRefPubMed
10.
Fang M, Zhang W, Chen Y, He Z: Malignant transformation of oral lichen planus: a retrospective study of 23 cases. Quintessence Int. 2009, 40: 235-242.PubMed
11.
Bornstein MM, Kalas L, Lemp S, Altermatt HJ, Rees TD, Buser D: Oral lichen planus and malignant transformation: a retrospective follow-up study of clinical and histopathologic data. Quintessence Int. 2006, 37: 261-271.PubMed
12.
Hobbs CG, Sterne JA, Bailey M, Heyderman RS, Birchall MA, Thomas SJ: Human papillomavirus and head and neck cancer: a systematic review and meta-analysis. Clin Otolaryngol. 2006, 31: 259-266. 10.1111/j.1749-4486.2006.01246.x.CrossRefPubMed
13.
Llewellyn CD, Johnson NW, Warnakulasuriya KA: Risk factors for squamous cell carcinoma of the oral cavity in young people–a comprehensive literature review. Oral Oncol. 2001, 37: 401-418. 10.1016/S1368-8375(00)00135-4.CrossRefPubMed
14.
O'Regan EM, Timon C, Sheils O, Codd M, O'Leary JJ, Toner M: Squamous cell carcinoma of the head and neck in young Irish adults. Br J Oral Maxillofac Surg. 2006, 44: 203-206. 10.1016/j.bjoms.2005.05.011.CrossRefPubMed
15.
Randhawa T, Shameena P, Sudha S, Nair R: Squamous cell carcinoma of tongue in a 19-year-old female. Indian J Cancer. 2008, 45: 128-130. 10.4103/0019-509X.44071.CrossRefPubMed
16.
Goldstein DP, Irish JC: Head and neck squamous cell carcinoma in the young patient. Curr Opin Otolaryngol Head Neck Surg. 2005, 13: 207-211. 10.1097/01.moo.0000170529.04759.4c.CrossRefPubMed
17.
Neglia JP, Friedman DL, Yasui Y, Mertens AC, Hammond S, Stovall M, Donaldson SS, Meadows AT, Robison LL: Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study. J Natl Cancer Inst. 2001, 93: 618-629. 10.1093/jnci/93.8.618.CrossRefPubMed
18.
Argani P, Laé M, Ballard ET, Amin M, Manivel C, Hutchinson B, Reuter VE, Ladanyi M: Translocation carcinomas of the kidney after chemotherapy in childhood. J Clin Oncol. 2006, 24: 1529-1534. 10.1200/JCO.2005.04.4693.CrossRefPubMed
19.
Bassal M, Mertens AC, Taylor L, Neglia JP, Greffe BS, Hammond S, Ronckers CM, Friedman DL, Stovall M, Yasui YY, et al: Risk of selected subsequent carcinomas in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2006, 24: 476-483. 10.1200/JCO.2005.02.7235.CrossRefPubMed
20.
Ochs J, Mulhern RK: Late effects of antileukemic treatment. Pediatr Clin North Am. 1988, 35: 815-833.PubMed
21.
Leung W, Ribeiro RC, Hudson M, Tong X, Srivastava DK, Rubnitz JE, Sandlund JT, Razzouk BI, Evans WE, Pui CH: Second malignancy after treatment of childhood acute myeloid leukemia. Leukemia. 2001, 15: 41-45. 10.1038/sj.leu.2401948.CrossRefPubMed
22.
Robison LL: Treatment-associated subsequent neoplasms among long-term survivors of childhood cancer: the experience of the Childhood Cancer Survivor Study. Pediatr Radiol. 2009, 39 (Suppl 1): S32-37.PubMedCentralCrossRefPubMed
23.
Inskip PD, Curtis RE: New malignancies following childhood cancer in the United States, 1973–2002. Int J Cancer. 2007, 121: 2233-2240. 10.1002/ijc.22827.CrossRefPubMed
24.
Maeda M: Late effects of childhood cancer: life-threatening issues. J Nippon Med Sch. 2008, 75: 320-324. 10.1272/jnms.75.320.CrossRefPubMed
25.
Evans WE, McLeod HL: Pharmacogenomics–drug disposition, drug targets, and side effects. N Engl J Med. 2003, 348: 538-549. 10.1056/NEJMra020526.CrossRefPubMed
26.
Oeffinger KC, McCabe MS: Models for delivering survivorship care. J Clin Oncol. 2006, 24: 5117-5124. 10.1200/JCO.2006.07.0474.CrossRefPubMed
Metadata
Title
Tongue cancer in young patients: case report of a 26-year-old patient
Authors
Aleksandra Credé
Michael Locher
Marius Bredell
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Head & Neck Oncology / Issue 1/2012
Electronic ISSN: 1758-3284
DOI
https://doi.org/10.1186/1758-3284-4-20

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