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Published in: Clinical Drug Investigation 2/2014

01-02-2014 | Case Report

Tocilizumab Monotherapy in a Patient with Rheumatoid Arthritis and Iatrogenic Kaposi Sarcoma

Authors: Francesca Ingegnoli, Athanasia Tourlaki, Roberta Gualtierotti

Published in: Clinical Drug Investigation | Issue 2/2014

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Abstract

Kaposi sarcoma (KS) is a human herpesvirus-8-associated lymphoangioproliferative neoplasm. Both human and viral interleukin-6 (IL-6) proteins seem to drive much of the clinical manifestations of KS, which provides a new target for intervention by using IL-6-neutralizing antibodies. We describe the clinical course of a patient in whom tocilizumab, a monoclonal anti-IL-6 receptor antibody approved for rheumatoid arthritis (RA) treatment, was effective not only in inducing RA remission but was also safe for KS.
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Metadata
Title
Tocilizumab Monotherapy in a Patient with Rheumatoid Arthritis and Iatrogenic Kaposi Sarcoma
Authors
Francesca Ingegnoli
Athanasia Tourlaki
Roberta Gualtierotti
Publication date
01-02-2014
Publisher
Springer International Publishing
Published in
Clinical Drug Investigation / Issue 2/2014
Print ISSN: 1173-2563
Electronic ISSN: 1179-1918
DOI
https://doi.org/10.1007/s40261-013-0159-9

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