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Diabetologia
Published in: Diabetologia 10/2004

01-10-2004 | Comment

—to: Weets I, Kaufman L, Van der Auwera B et al. (2004) Seasonality in clinical onset of Type 1 diabetes in Belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence. Diabetologia 47:614–621

Author: B. J. Boucher

Published in: Diabetologia | Issue 10/2004

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Excerpt

To the Editor: I read the paper by Weets and co-workers [1] reporting seasonality of onset of Type 1 diabetes in HLA-DQ2/DQ8-negative Belgian males with interest. One of the possible environmental factors that vary with season in Europeans and are discussed by the authors of this paper as possible determinants of Type 1 diabetes is vitamin D deficiency, a factor which might explain the authors’ findings as a result of interactions with genetic factors. …
Literature
1.
Weets I, Kaufman L, Van der Auwera B et al. (2004) Seasonality in clinical onset of Type 1 diabetes in Belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence. Diabetologia 47:614–621CrossRefPubMed
2.
EURODIAB Study Group 2 (1999) Vitamin D supplement in early childhood and risk for Type 1 (insulin-dependent) diabetes mellitus. The EURODIAB Substudy 2 Study Group. Diabetologia 42:51–54CrossRefPubMed
3.
Stene LC, Joner G (2003) Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large population-based, case-control study. Am J Clin Nutr 78:1128–1134PubMed
4.
Hypponen E, Laara E, Reunanen A et al. (2001) Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 358:1500–1503CrossRefPubMed
5.
Boucher BJ, Robinson S, Shore S et al. (2003) Maternal vitamin D status contributes inversely to cord proinsulin and directly to abdominal girth in white babies born in southern England. Ped Res 53:14A
Metadata
Title
—to: Weets I, Kaufman L, Van der Auwera B et al. (2004) Seasonality in clinical onset of Type 1 diabetes in Belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence. Diabetologia 47:614–621
Author
B. J. Boucher
Publication date
01-10-2004
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 10/2004
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-004-1539-8

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