Skip to main content
Top
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2019

01-06-2019 | Original Article

To Evaluate the Role of H. pylori in Patients with Chronic Recurrent Tonsillitis

Authors: Suresh Mani, Assadi Rekha, Muthiah Kothanda Ramanujam Srinivasan, Venkatasubramanyam Bhanumathy

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 2/2019

Login to get access

Abstract

The usual indication for surgical resection of tonsils is chronic recurrent tonsillitis. Literature also does not indicate the reason behind the fact that only part of the population suffers from recurrent chronic tonsillitis in spite being exposed to similar conditions. This was a prospective study, in which 50 tonsil biopsy samples obtained from chronic tonsillitis patients. Specimens were analysed with rapid urease broth test, HelicotecUT PLUS assay and Toluidine blue staining for presence of Helicobacter pylori. The age ranged from 4 to 34 years. The median age for patients with chronic recurrent tonsillitis was 9.5, 23 (46%) patients were male while 27 (54%) were female, presence of H. pylori by rapid urease broth test, HelicotecUT PLUS assay and Histopathology was 4%. Our analysis revealed that H. pylori did not significantly colonize the tonsils and does not play a role in the pathogenesis or development of chronic tonsillitis. The heterogeneity in study population and methodology may have contributed to the non significant results.
Literature
1.
2.
go back to reference Cammarota GA, Tursi L, Marinis De, Papa A, Valle D, Cuoco L et al (1997) Gastric mucosa-associated lymphoid tissue in autoimmune thyroid diseases. Scand J Gastroenterol 32(9):869–872CrossRefPubMed Cammarota GA, Tursi L, Marinis De, Papa A, Valle D, Cuoco L et al (1997) Gastric mucosa-associated lymphoid tissue in autoimmune thyroid diseases. Scand J Gastroenterol 32(9):869–872CrossRefPubMed
3.
go back to reference Pytko-Polonczyk J, Konturek SJ, Karczewska E, Bielański W, Kaczmarczyk-Stachowska A (1996) Oral cavity as permanent reservoir of Helicobacter pylori and potential source of re infection. J Physiol Pharmacol 47(1):121–129PubMed Pytko-Polonczyk J, Konturek SJ, Karczewska E, Bielański W, Kaczmarczyk-Stachowska A (1996) Oral cavity as permanent reservoir of Helicobacter pylori and potential source of re infection. J Physiol Pharmacol 47(1):121–129PubMed
4.
5.
go back to reference Paradise JL, Bluestone CD, Bachman RZ et al (1984) Efficacy of tonsillectomy for recurrent throat infection in severely affected children. Results of parallel randomized and nonrandomized clinical trials. N Engl J Med 310:674–683CrossRefPubMed Paradise JL, Bluestone CD, Bachman RZ et al (1984) Efficacy of tonsillectomy for recurrent throat infection in severely affected children. Results of parallel randomized and nonrandomized clinical trials. N Engl J Med 310:674–683CrossRefPubMed
6.
go back to reference Khademi B, Imanieh MH, Gandomi B, Yeganeh F, Niknejad N (2005) Investigation of H. pylori colonization in adenotonsillectomy specimens by means of rapid urease (CLO) test. Iran J Med Sci 30(3):54–65 Khademi B, Imanieh MH, Gandomi B, Yeganeh F, Niknejad N (2005) Investigation of H. pylori colonization in adenotonsillectomy specimens by means of rapid urease (CLO) test. Iran J Med Sci 30(3):54–65
7.
go back to reference Peter Ochung O, Mugwe P, Masinde P, Waweru W (2015) The prevalence of H. pylori in tonsillar tissue of patients with adenotonsillar hypertrophy using Rapid Urease Test in a tertiary hospital in a sub Saharan country. Indian J Otolaryngol Head Neck Surg 67(3):223–226CrossRef Peter Ochung O, Mugwe P, Masinde P, Waweru W (2015) The prevalence of H. pylori in tonsillar tissue of patients with adenotonsillar hypertrophy using Rapid Urease Test in a tertiary hospital in a sub Saharan country. Indian J Otolaryngol Head Neck Surg 67(3):223–226CrossRef
8.
go back to reference Woolford TJ, Hanif J, Washband S, Hari CK, Ganguli LA (1999) The effect of previous antibiotic therapy on the bacteriology of the tonsils in children. Int J Clin Pract 53(2):96–98PubMed Woolford TJ, Hanif J, Washband S, Hari CK, Ganguli LA (1999) The effect of previous antibiotic therapy on the bacteriology of the tonsils in children. Int J Clin Pract 53(2):96–98PubMed
9.
go back to reference Stoodley P, Debeer D, Longwell M, Nistico L, Hall-Stoodley L, Wenig B (2009) Tonsillolith: not just a stone but a living biofilm. Otolaryngol Head Neck Surg 141:316–321CrossRefPubMed Stoodley P, Debeer D, Longwell M, Nistico L, Hall-Stoodley L, Wenig B (2009) Tonsillolith: not just a stone but a living biofilm. Otolaryngol Head Neck Surg 141:316–321CrossRefPubMed
10.
go back to reference Ramírez A, Peidrola D, López A, Martínez MD, Ros MJ, Corral JL, Arteaga E (1997) Beta-hemolytic streptococci in tonsil hypertrophy and recurrent tonsillitis. Enferm Infecc Microbiol Clin 15(6):315–318PubMed Ramírez A, Peidrola D, López A, Martínez MD, Ros MJ, Corral JL, Arteaga E (1997) Beta-hemolytic streptococci in tonsil hypertrophy and recurrent tonsillitis. Enferm Infecc Microbiol Clin 15(6):315–318PubMed
11.
go back to reference Zahedi MJ, Moghadam SD, Mosavi MA, Mirshekari T, Hayatbakhsh M (2009) Helicobacter pylori colonization in biopsies of the adenotonsillectomy specimens. Am J Appl Sci 6(12):2050–2053CrossRef Zahedi MJ, Moghadam SD, Mosavi MA, Mirshekari T, Hayatbakhsh M (2009) Helicobacter pylori colonization in biopsies of the adenotonsillectomy specimens. Am J Appl Sci 6(12):2050–2053CrossRef
12.
go back to reference Kariya Shin, Okano Mitsuhiro, Nishizaki Kazunori (2014) An association between Helicobacter pylori and upper respiratory tract disease: fact or fiction? World J Gastroenterol 20(6):1470–1484CrossRefPubMedPubMedCentral Kariya Shin, Okano Mitsuhiro, Nishizaki Kazunori (2014) An association between Helicobacter pylori and upper respiratory tract disease: fact or fiction? World J Gastroenterol 20(6):1470–1484CrossRefPubMedPubMedCentral
13.
go back to reference Hwang MS, Forman SN, Kanter JA, Friedman M (2015) Tonsillar Helicobacter pylori colonization in chronic tonsillitis systematic review and meta-analysis. JAMA Otolaryngol Head Neck Surg 141(3):245–249CrossRefPubMed Hwang MS, Forman SN, Kanter JA, Friedman M (2015) Tonsillar Helicobacter pylori colonization in chronic tonsillitis systematic review and meta-analysis. JAMA Otolaryngol Head Neck Surg 141(3):245–249CrossRefPubMed
14.
go back to reference Sakonlaya D, Apisarnthanarak A, Yamada N, Tomtitchong P (2014) Modified toluidine blue: an alternative stain for Helicobacter pylori detection in routine diagnostic use and post-eradication confirmation for gastric cancer prevention. Asian Pac J Cancer Prev 15(16):6983–6987CrossRefPubMed Sakonlaya D, Apisarnthanarak A, Yamada N, Tomtitchong P (2014) Modified toluidine blue: an alternative stain for Helicobacter pylori detection in routine diagnostic use and post-eradication confirmation for gastric cancer prevention. Asian Pac J Cancer Prev 15(16):6983–6987CrossRefPubMed
Metadata
Title
To Evaluate the Role of H. pylori in Patients with Chronic Recurrent Tonsillitis
Authors
Suresh Mani
Assadi Rekha
Muthiah Kothanda Ramanujam Srinivasan
Venkatasubramanyam Bhanumathy
Publication date
01-06-2019
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 2/2019
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-018-1313-8

Other articles of this Issue 2/2019

Indian Journal of Otolaryngology and Head & Neck Surgery 2/2019 Go to the issue