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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 4/2014

01-04-2014 | Hepatobiliary Tumors

Timing of Liver Surgery for Colorectal Liver Metastases will be Influenced by Tumor Behavior

Authors: François Cauchy, MD, Jacques Belghiti, MD

Published in: Annals of Surgical Oncology | Issue 4/2014

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Excerpt

We all know that surgery remains the best chance of cure for patients with colorectal liver metastases (CLM). Within 2 years following resection, half of the patients will experience recurrence, but it is commonly accepted that repeat resection, when technically feasible, provides excellent long-term outcomes, joining that of patients without recurrence.1 One should nevertheless bear in mind that these prolonged survivals are often the result of the multimodal management of the patients, which combines sophisticated morphological follow-up, percutaneous ablative therapies and, above all, systemic chemotherapy. …
Literature
1.
Wicherts DA, de Haas RJ, Salloum C, Andreani P, Pascal G, Sotirov D, et al. Repeat hepatectomy for recurrent colorectal metastases. Br J Surg. 2013;100:808–18.PubMedCrossRef
2.
Viganò L, Capussotti L, Lapointe R, Barroso E, Hubert C, Giuliante F, et al. Early recurrence after liver resection for colorectal metastases: risk factors, prognosis, and treatment. A LiverMetSurvey-based study of 6025 patients. Ann Surg Oncol. doi:10.​1245/​s10434-013-3421-8.
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Mentha G, Terraz S, Morel P, Andres A, Giostra E, Roth A, et al. Dangerous halo after neoadjuvant chemotherapy and two-step hepatectomy for colorectal liver metastases. Br J Surg. 2009;96:95–103.PubMedCrossRef
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Torzilli G, Montorsi M, Donadon M, Palmisano A, Del Fabbro D, Gambetti A, et al. “Radical but conservative” is the main goal for ultrasonography-guided liver resection: prospective validation of this approach. J Am Coll Surg. 2005;201:517–28.PubMedCrossRef
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Cauchy F, Aussilhou B, Dokmak S, Fuks D, Gaujoux S, Farges O, et al. Reappraisal of the risks and benefits of major liver resection in patients with initially unresectable colorectal liver metastases. Ann Surg. 2012;256:746–52.PubMedCrossRef
Metadata
Title
Timing of Liver Surgery for Colorectal Liver Metastases will be Influenced by Tumor Behavior
Authors
François Cauchy, MD
Jacques Belghiti, MD
Publication date
01-04-2014
Publisher
Springer US
Published in
Annals of Surgical Oncology / Issue 4/2014
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-013-3423-6

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