Skip to main content
Top
Published in: Indian Journal of Surgical Oncology 4/2019

01-12-2019 | Thyroidectomy | Case Report

A Case Rarity: Papillary Thyroid Carcinoma with Squamous Metaplasia Complicated with Chronic Discharging Ulcers

Authors: Wan Fatihah Wan Sohaimi, Y. F. Lee, Norazlina Mat Nawi, Mohd Fazrin Mohd Rohani, Nur Asma Sapiai

Published in: Indian Journal of Surgical Oncology | Issue 4/2019

Login to get access

Abstract

We report a unique case of differentiated thyroid carcinoma (DTC) with squamous metaplasia complicated with chronic discharging ulcer. A 76-year-old gentleman was referred to us after defaulted treatment 1 year post-total thyroidectomy. He presented to us with long-standing chronic, non-healing, ulcerative and discharging wound at the anterior neck at previous total thyroidectomy scar. The primary tumour was histologically diagnosed as papillary malignant cells with extensive squamous metaplasia. Squamous metaplasia is a rare finding in thyroid carcinoma that carried a poorer prognostic factor.
Literature
1.
go back to reference Kitahara S, Ito T, Hamatani S, Shibuya K, Shiba T (2006) Thyroid papillary carcinoma recurring as squamous cell carcinoma: report of a case. Surg Today 36(2):171–174CrossRef Kitahara S, Ito T, Hamatani S, Shibuya K, Shiba T (2006) Thyroid papillary carcinoma recurring as squamous cell carcinoma: report of a case. Surg Today 36(2):171–174CrossRef
2.
go back to reference Kunisue H, Mikami Y, Tanaka K, Sonoo H, Udagawa K, Yamamoto Y, Yamamoto S, Kurebayashi J, Shimozuma K (2003) Metastatic papillary thyroid carcinoma of the submandibular lymph nodes with extensive squamous metaplasia: report of a case. Surg Today 33(10):751–754CrossRef Kunisue H, Mikami Y, Tanaka K, Sonoo H, Udagawa K, Yamamoto Y, Yamamoto S, Kurebayashi J, Shimozuma K (2003) Metastatic papillary thyroid carcinoma of the submandibular lymph nodes with extensive squamous metaplasia: report of a case. Surg Today 33(10):751–754CrossRef
3.
go back to reference Harish K (2008) Thyroid carcinoma with discharging sinus - a rarity: a case report. J Med Case Rep 2:4–6CrossRef Harish K (2008) Thyroid carcinoma with discharging sinus - a rarity: a case report. J Med Case Rep 2:4–6CrossRef
4.
go back to reference Gonzalez-Gonzalez R, Bologna-Molina R, Carreon-Burciaga RG, Gómezpalacio-Gastelum M, Molina-Frechero N, Salazar-Rodríguez S (2011) Papillary thyroid carcinoma: differential diagnosis and prognostic values of its different variants: review of the literature. ISRN Oncol 2011:1–9CrossRef Gonzalez-Gonzalez R, Bologna-Molina R, Carreon-Burciaga RG, Gómezpalacio-Gastelum M, Molina-Frechero N, Salazar-Rodríguez S (2011) Papillary thyroid carcinoma: differential diagnosis and prognostic values of its different variants: review of the literature. ISRN Oncol 2011:1–9CrossRef
5.
go back to reference Livolsi VA (2011) Papillary thyroid carcinoma: an update. Mod Pathol 24:S1–S9CrossRef Livolsi VA (2011) Papillary thyroid carcinoma: an update. Mod Pathol 24:S1–S9CrossRef
6.
go back to reference Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE et al (2016) 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid 26(1):1–133CrossRef Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE et al (2016) 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid 26(1):1–133CrossRef
7.
go back to reference Eom TI, Koo BY, Kim BS, Kang KH, Jung SK, Jun SY, Bae HS, Kim LS (2008) Coexistence of primary squamous cell carcinoma of thyroid with classic papillary thyroid carcinoma. Pathol Int 58(12):797–800CrossRef Eom TI, Koo BY, Kim BS, Kang KH, Jung SK, Jun SY, Bae HS, Kim LS (2008) Coexistence of primary squamous cell carcinoma of thyroid with classic papillary thyroid carcinoma. Pathol Int 58(12):797–800CrossRef
8.
go back to reference Tunio MA, Al AM, Fagih M, Akasha R (2012) Primary squamous cell carcinoma of kidney- a case report and review of literature. Head Neck Oncol 4:8CrossRef Tunio MA, Al AM, Fagih M, Akasha R (2012) Primary squamous cell carcinoma of kidney- a case report and review of literature. Head Neck Oncol 4:8CrossRef
9.
go back to reference Tovi F, Goldstein J (1985) Locally aggressive differentiated thyroid carcinoma. J Surg Oncol 29:99–104CrossRef Tovi F, Goldstein J (1985) Locally aggressive differentiated thyroid carcinoma. J Surg Oncol 29:99–104CrossRef
10.
go back to reference Safer JD, Crawford TM, Holick MF (2004) A role for thyroid hormone in wound healing through keratin gene expression. Endocrinology. 145(5):2357–2361CrossRef Safer JD, Crawford TM, Holick MF (2004) A role for thyroid hormone in wound healing through keratin gene expression. Endocrinology. 145(5):2357–2361CrossRef
11.
go back to reference Deasy J, Prichard R, Evoy D, McDermott E (2010) The role of thyrotropin suppression in patients with differentiated thyroid carcinoma. Ir Med J 103:2–5 Deasy J, Prichard R, Evoy D, McDermott E (2010) The role of thyrotropin suppression in patients with differentiated thyroid carcinoma. Ir Med J 103:2–5
12.
go back to reference Shaha AR (2008) Revision thyroid surgery – technical considerations. Otolaryngol Clin North Am 41:1169–1183CrossRef Shaha AR (2008) Revision thyroid surgery – technical considerations. Otolaryngol Clin North Am 41:1169–1183CrossRef
13.
go back to reference Kinuya S, Yokoyama K, Michigishi T, Tonami N (2006) Respiratory distress caused by radioiodine therapy in patients with differentiated thyroid cancer. Ann Nucl Med 20(7):499–502CrossRef Kinuya S, Yokoyama K, Michigishi T, Tonami N (2006) Respiratory distress caused by radioiodine therapy in patients with differentiated thyroid cancer. Ann Nucl Med 20(7):499–502CrossRef
Metadata
Title
A Case Rarity: Papillary Thyroid Carcinoma with Squamous Metaplasia Complicated with Chronic Discharging Ulcers
Authors
Wan Fatihah Wan Sohaimi
Y. F. Lee
Norazlina Mat Nawi
Mohd Fazrin Mohd Rohani
Nur Asma Sapiai
Publication date
01-12-2019
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 4/2019
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-019-00977-8

Other articles of this Issue 4/2019

Indian Journal of Surgical Oncology 4/2019 Go to the issue