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01-12-2019 | Sine qua non Radiology-Pathology

Thyroid-Like Low-Grade Nasopharyngeal Papillary Adenocarcinoma

Authors: Kerry B. Baumann, Sasha J. Betz

Published in: Head and Neck Pathology | Issue 4/2019

Abstract

Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma (TL-LGNPPA) is a rare entity. Patients often present with complaints of nasal fullness, obstruction, and epistaxis. It may be confused with metastatic papillary thyroid carcinoma due to its histologic similarity and overlapping immunohistochemical studies, but it is important to distinguish between the two because of differing treatment modalities and prognosis. A significant difference between the two is that despite both entities demonstrating TTF-1 positivity, TL-LGNPPA usually does not stain for thyroglobulin. TL-LGNPPA exhibits indolent growth, with no incidence of metastasis or recurrence after surgical excision.

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Title: Thyroid-Like Low-Grade Nasopharyngeal Papillary Adenocarcinoma
Authors: Kerry B. Baumann
Sasha J. Betz
Publication date: 01-12-2019
Publisher: Springer US
Published in: Head and Neck Pathology / Issue 4/2019
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-018-0947-x

At a glance: The STEP trials

Springer Medicine

Thyroid-Like Low-Grade Nasopharyngeal Papillary Adenocarcinoma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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