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01-02-2022 | Thrombotic Microangiopathy | Educational Review

Role of therapeutic apheresis in the treatment of pediatric kidney diseases

Authors: Shweta Shah, Catherine Joseph, Poyyapakkam Srivaths

Published in: Pediatric Nephrology | Issue 2/2022

Abstract

Therapeutic apheresis utilizes apheresis procedures in the treatment of a variety of conditions including kidney disease. Therapeutic plasma exchange (TPE) is the most common modality employed with the rationale of rapid reduction of a pathogenic substance distributed primarily in the intravascular compartment; however other techniques which adsorb such pathogenic substances or alter the immune profile have been utilized in diseases affecting native and transplanted kidneys. This article discusses the modalities and technical details of therapeutic apheresis and summarizes its role in individual diseases affecting the kidney. Complications related to pediatric apheresis procedures and specifically related to apheresis in kidney disease are also discussed. Though therapeutic apheresis modalities are employed frequently in children with kidney disease, most experiences are extrapolated from adult studies. International and national registries need to be established to elucidate the role of apheresis modalities in children with kidney disease.

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Title: Role of therapeutic apheresis in the treatment of pediatric kidney diseases
Authors: Shweta Shah
Catherine Joseph
Poyyapakkam Srivaths
Publication date: 01-02-2022
Publisher: Springer Berlin Heidelberg
Keyword: Thrombotic Microangiopathy
Published in: Pediatric Nephrology / Issue 2/2022
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-021-05093-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Role of therapeutic apheresis in the treatment of pediatric kidney diseases

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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