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Open Access 01-12-2023 | Thoracotomy | Case Report

Surgical removal of an unusual huge solitary fibrous tumor in the mediastinum: a case report

Authors: Parviz Mardani, Mohammad Nekooeian, Saba Zangeneh, Hooman Kamran, Reza Shahriarirad, Mohammad Hossein Anbardar, Armin Amirian, Masoud Vafabin

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

Abstract

Background

Intrathoracic Solitary Fibrous Tumors (SFT) mainly arise from the pleura; however, these tumors may also originate from the mediastinum. We present a rare case of posterior SFT extending to several mediastinal sites and with an unusual large size, successfully treated with surgical resection.

Case presentation

A 66-year-old female presented with an initial manifestation of ambiguous pain in the chest and dysphagia and later developed pitting edema in both lower extremities and cachexia five months before admission. Chest imaging confirmed a mediastinal mass (17 × 15 × 8 cm) which was surgically removed. Immunohistochemistry confirmed the diagnosis of a solitary fibrous tumor with positive B-cell lymphoma 2, STAT6, and CD99, negative S100 and smooth muscle actin, and low levels of Ki67 (5–7%). The patient’s follow-up course was unremarkable.

Conclusion

Mediastinal SFTs may grow extremely huge, with the potential to invade multiple adjacent sites. Surgical removal of the tumor remains the mainstay of treatment in these cases.

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Title: Surgical removal of an unusual huge solitary fibrous tumor in the mediastinum: a case report
Authors: Parviz Mardani
Mohammad Nekooeian
Saba Zangeneh
Hooman Kamran
Reza Shahriarirad
Mohammad Hossein Anbardar
Armin Amirian
Masoud Vafabin
Publication date: 01-12-2023
Publisher: BioMed Central
Keyword: Thoracotomy
Published in: Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-023-02366-3

2024 ASCO Annual Meeting

Springer Medicine

Surgical removal of an unusual huge solitary fibrous tumor in the mediastinum: a case report

Abstract

Background

Case presentation

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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