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01-06-2011 | Brief Communication

Thoracic and abdominal mesothelioma in a dog: a cytologist’s view

Authors: Danieli Brolo Martins, Giancarlo S. Souza, Josaine C. S. R. Pedrozo, Cinthia M. Mazzanti, Alexandre Mazzanti, Diego V. Beckmann, Rosmarini Passos Santos, Dominguita L. Graça, Sonia T. A. Lopes

Published in: Comparative Clinical Pathology | Issue 3/2011

Abstract

Mesothelioma is an uncommon tumour in dogs, whose diagnosis can be a challenge to the veterinary cytologist. This paper aims to report a case of mesothelioma in a dog, obtained from the cytological analysis of pleural and abdominal fluid, which allowed an in vivo diagnosis. A 4.10-year-old-boxer dog was presented for clinical care with abdominal distension, difficulty in breathing and loss of appetite. Laboratorial and imaging tests were performed, and the cytology of abdominal and pleural effusions suggested the presence of mesothelioma. The cytology was ratified later by a histopathology of the lungs, ovaries, liver, spleen, peritoneum and omentum.

Alleman AR (2003) Abdominal, thoracic, and pericardial effusions. Vet Clin Small Anim 33:89–118CrossRef

Amaya JO, Arevalo GH (2008) Mesotelioma invasive de un canino: citologia, clínica e hallazgos patológicos. Int J Morphol 26:103–112

Avakian A, Alroy J, Rozanski E, Keating J, Rosenberg A (2008) Lipid-rich pleural mesothelioma in a dog. J Vet Diagn Invest 20:665–667PubMed

Beytut E (2002) Metastatic sclerosing mesothelioma in a cow. Aust Vet J 80:409–411PubMedCrossRef

Birgegard G, Aapro MS, Bokemeyer C, Dicato M, Drings P, Hornedo J, Krzakowski M, Ludwig H, Pecorelli S, Schmoll H, Schneider M, Schrijvers D, Shasha D, Van Belle S (2005) Cancer-related anemia: pathogenesis, prevalence and treatment. Oncology 68:3–11. doi:10.1159/000083128 PubMedCrossRef

Carbone M, Bedrossian CWM (2006) The pathogenesis of mesothelioma. Semin Diagn Pathol 23:56–60. doi:10.1053/j.semdp.2006.08.002 PubMedCrossRef

Cassali GD, Gartner F, Vieira da Silva MJ, Schmitt FC (1999) Cytological diagnosis of a metastatic canine mammary tumor in pleural effusion. Arq Bras Med Vet Zootec 51:307–310. doi:10.1590/S0102-09351999000400003 CrossRef

Churg A, Colby TV, Cagle P, Corson J, Gibbs AR, Glks B, Grimes M, Hammar S, Roggli V, Travis WD (2000) The separation of benign and malignant mesothelial proliferations. Am J Surg Pathol 24:1183–1200PubMedCrossRef

Connally HE (2003) Citology and fluid analysis of the acute abdomen. Clin Tech Small Anim Pract 18:39–44. doi:10.1016/1096-2867(03)90024-7 PubMedCrossRef

Echandi RL, Morandi F, Newman SJ, Holford A (2007) Imaging diagnosis—canine thoracic mesothelioma. Vet Radiol Ultrasound 48:243–245. doi:10.1111/j.1740-8261.2007.00236.x PubMedCrossRef

Geninet C, Bernex F, Rakotovao F, Crespeau FL, Parodi AL, Fontaine JJ (2003) Sclerosing peritoneal mesothelioma in a dog—a case report. J Vet Med 50:402–405CrossRef

Guedes RMC, Zica KGB, Coelho-Guedes MIM, Oliveira SR (2000) Accuracy of cytological exam for diagnosis of inflammatory and proliferative process in domestic animals. Arq Bras Med Vet Zootec 52:437–439. doi:10.1590/S0102-09352000000500004 CrossRef

Hirschberger J, DeNicola DB, Hermanns W, Kraft W (1999) sensitivity and specificity of cytologic evaluation in the diagnosis of neoplasia in body fluids from dogs and cats. Vet Clin Pathol 28:142–146. doi:10.1111/j.1939-165X.1999.tb01065.x PubMedCrossRef

Jones MA, Young RH, Scully RE (1995) Malignant mesothelioma of the tunica vaginalis—a clinicopathologic analysis of 11 cases with review of the literature. Am J Surg Pathol 19:815–825PubMedCrossRef

Kaneko JJ, Harvey JW, Bruss ML (2008) Appendix IX blood analyte reference values in small and some laboratory animals. In: Clinical Biochemistry of Domestic Animals, 6th edn. Academic, New York, pp 889–895

Kavula LA, Latimer KS, Bain PJ (2009) Mesothelioma in dogs. Veterinary Clinical Pathology Clerkship Program. http://www.vet.uga.edu/vpp/clerk/kavula/#. Accessed 18 October 2009.

Kim JH, Choi YK, Yoon HY, Kweon OK, Kim DY (2002) Juvenile malignant mesothelioma in a dog. J Vet Med Sci 64:269–271PubMedCrossRef

Krametter R, Bago Z, Floeck M, Baumgartner W (2004) Abdominal mesothelioma in a goat. N Z Vet J 52:293–296PubMedCrossRef

Meinkoth JH, Cowell RL, Tyler RD (2009a) Cell types and criteria of malignancy. In: Cowell RL, Tyler RD, Meinkoth JH, DeNicola DB (eds) Diagnostic Cytology and Hematology of the Dog and Cat, 3rd edn. Mosby Elsevier, St Louis, pp 20–46

Meinkoth JH, Cowell RL, Tyler RD, Morton RJ (2009b) Sample collection and preparation. In: Cowell RL, Tyler RD, Meinkoth JH, DeNicola DB (eds) Diagnostic Cytology and Hematology of the Dog and Cat, 3rd edn. Mosby Elsevier, St Louis, pp 1–19

Merlo WA, Rosciani AS, Koscinczuk P, Ortega HH, Insfrán RM, Macció OA (2007) Mesotelioma peritoneal en un canino. Rev Vet 18:55–57

Misdorp W (2002) Tumours in calves: comparative aspects. J Comp Path 127:96–105. doi:10.1053/jcpa.2002.0563 PubMedCrossRef

Moore AJ, Parker RJ, Wiggins J (2008) Malignant mesothelioma. Orphanet J Rare Dis 3:34. doi:10.1186/1750-1172-3-34 PubMedCrossRef

Morris J, Dobson J (2007) Oncologia em Pequenos Animais (Small Animals Oncology), 1st edn. São Paulo, Roca, p 300p

Moulton JE (1990) Tumours of domestic animals, 3rd edn. California, Berkeley, 672p

Movassaghi AR, Maleki M, Khanzadi S (2009) Primary pericardial mesothelioma in a sheep. Comp Clin Pathol 18:459–461. doi:10.1007/s00580-008-0805-4 CrossRef

Piancenti AM, Ocarino NM, Silva AE, Rachid MA, França SA, Serakides R (2004) Pleural mesothelioma with renal metastasis in a cat. Arq Bras Med Vet Zootec 56:558–561CrossRef

Reggeti F, Brisson B, Ruotsalo K, Southorn E, Bienzle D (2005) Invasive epithelial mesothelioma in a dog. Vet Pathol 42:77–81PubMedCrossRef

Renshaw AA, Dean BR, Antman KH, Sugarbaker DJ, Cibas ES (1997) The role of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma. Chest 111:106–109PubMedCrossRef

Rizzi TE, Cowell RL, Tyler RD, Meinkoth JH (2009) Effusions: abdominal, thoracic, and pericardial. In: Cowell RL, Tyler RD, Meinkoth JH, DeNicola DB (eds) Diagnostic Cytology and Hematology of the Dog and Cat, 3rd edn. Mosby Elsevier, St Louis, pp 235–255

Serakides R, Cassali GD, SantAna FJF, Nascimento EF (2001) Peritoneal mesothelioma in a dog: a case report. Arq Bras Med Vet Zootec 53:1–5. doi:10.1590/S0102-09352001000200009

Ulrich R, Eydner M, Grün A, Haydn J, Baumgärtner W (2009) A biphasic malignant mesothelioma of the peritoneum and pleura in a horse. Dtsch Tierärztl Wochenschr 116:186–191PubMed

Vural SA, Ozyildiz Z, Ozsoy SY (2007) Pleural mesothelioma in a nine-month-old dog. Ir Vet J 60:30–33CrossRef

Wilson DW, Dungworth DL (2002) Tumors of the respiratory tract. In: Meuten DJ (ed) Tumors in Domestic Animals, 4th edn. Blackwell, Iowa, pp 365–399CrossRef

Title: Thoracic and abdominal mesothelioma in a dog: a cytologist’s view
Authors: Danieli Brolo Martins
Giancarlo S. Souza
Josaine C. S. R. Pedrozo
Cinthia M. Mazzanti
Alexandre Mazzanti
Diego V. Beckmann
Rosmarini Passos Santos
Dominguita L. Graça
Sonia T. A. Lopes
Publication date: 01-06-2011
Publisher: Springer-Verlag
Published in: Comparative Clinical Pathology / Issue 3/2011
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-011-1177-8

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Thoracic and abdominal mesothelioma in a dog: a cytologist’s view

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