Published in:
Open Access
01-12-2015 | Oral presentation
The value of evidence synthesis in randomised controlled trial (RCT) design, conduct and analysis: MRC clinical trials unit (CTU) at UCL experience
Authors:
Jayne F Tierney, Sarah Burdett, Claire Vale, Larysa Rydzewska, Matthew R Sydes, Ruth E Langley, Richard S Kaplan, Mahesh KB Parmar
Published in:
Trials
|
Special Issue 2/2015
Login to get access
Excerpt
Systematic reviews of RCTs are recognised as the optimal way to resolve or confirm uncertainty about the effects of interventions. They can provide the rationale for the design of a new trial, inform the conduct of an ongoing trial, and help place trial results in the context of those from related trials. However, empirical evidence suggests that few trials use systematic reviews in these ways. …