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Published in: Trials 2/2015

Open Access 01-12-2015 | Oral presentation

The value of evidence synthesis in randomised controlled trial (RCT) design, conduct and analysis: MRC clinical trials unit (CTU) at UCL experience

Authors: Jayne F Tierney, Sarah Burdett, Claire Vale, Larysa Rydzewska, Matthew R Sydes, Ruth E Langley, Richard S Kaplan, Mahesh KB Parmar

Published in: Trials | Special Issue 2/2015

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Excerpt

Systematic reviews of RCTs are recognised as the optimal way to resolve or confirm uncertainty about the effects of interventions. They can provide the rationale for the design of a new trial, inform the conduct of an ongoing trial, and help place trial results in the context of those from related trials. However, empirical evidence suggests that few trials use systematic reviews in these ways. …
Metadata
Title
The value of evidence synthesis in randomised controlled trial (RCT) design, conduct and analysis: MRC clinical trials unit (CTU) at UCL experience
Authors
Jayne F Tierney
Sarah Burdett
Claire Vale
Larysa Rydzewska
Matthew R Sydes
Ruth E Langley
Richard S Kaplan
Mahesh KB Parmar
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Trials / Issue Special Issue 2/2015
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/1745-6215-16-S2-O4

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