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01-12-2021 | ORIGINAL ARTICLE

The utility of heart-to-mediastinum ratio using a planar image created from IQ-SPECT with Iodine-123 meta-iodobenzylguanidine

Authors: Takayuki Shibutani, PhD, Kenichi Nakajima, MD, PhD, Hiroto Yoneyama, PhD, Takahiro Konishi, MS, Koichi Okuda, PhD, Masahisa Onoguchi, PhD, Seigo Kinuya, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 6/2021

Abstract

Aims

¹²³I-labeled meta-iodobenzylguanidine (MIBG) has used a planar image to measure the heart-to-mediastinum ratio (HMR). However, planar images are not available from IQ-SPECT with SMARTZOOM collimator due to its multi-focal collimation. Since we created the planar-equivalent (IQ-planar) images by adding all slices of the IQ-SPECT coronal image. The aim of this study was to demonstrate the utility of the new method for calculating HMR.

Methods

The planar image and transverse images of IQ-SPECT with attenuation and scatter corrections (ACSC) and without ACSC (NC) were obtained. Multi-planar reconstruction and ray-summation processing were applied to create IQ-planar images with NC and ACSC. Linear regression between the measured HMR from the planar image and the mathematically calculated HMR was used to calibrate HMR to standardized values.

Results

Scatterplots and linear regression lines between planar and IQ-planar HMRs before and after cross-calibration showed systematic differences in both NC and ACSC conditions. The IQ-planar HMR with NC and ACSC was significantly higher compared with that of the conventional planar image. However, the IQ-planar HMR with NC and ACSC after cross-calibration was similar to the standardized HMR calculated by planar image.

Conclusion

The IQ-planar HMR using the new ray-summation processing method could be used along with the conventional planar HMR.

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Title: The utility of heart-to-mediastinum ratio using a planar image created from IQ-SPECT with Iodine-123 meta-iodobenzylguanidine
Authors: Takayuki Shibutani, PhD
Kenichi Nakajima, MD, PhD
Hiroto Yoneyama, PhD
Takahiro Konishi, MS
Koichi Okuda, PhD
Masahisa Onoguchi, PhD
Seigo Kinuya, MD, PhD
Publication date: 01-12-2021
Publisher: Springer International Publishing
Published in: Journal of Nuclear Cardiology / Issue 6/2021
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-020-02081-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The utility of heart-to-mediastinum ratio using a planar image created from IQ-SPECT with Iodine-123 meta-iodobenzylguanidine

Abstract

Aims

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Aims

Methods

Results

Conclusion

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