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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-12-2017 | Retinal Disorders

The use of optical coherence tomography angiography in pachychoroid spectrum diseases: a concurrent comparison with dye angiography

Authors: Sibel Demirel, Özge Yanık, Hilal Nalcı, Figen Batıoğlu, Emin Özmert

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2017

Abstract

Purpose

The study objective was to compare dye angiography and optical coherence tomography angiography (OCTA) in detecting choroidal neovascuarization (CNV) in patients presenting with pachychoroid features and flat irregular pigment epithelial detachment (PED).

Methods

Nineteen eyes of 17 patients, presenting with flat PED and pachychoroid features, and without age-related macular degeneration or any other degenerative change, were analyzed. Fuorescein angiography (FA)/Indocyanine green angiography (ICGA) and OCTA were performed during the same visit. Subfoveal choroidal thickness was measured by enhanced depth imaging using spectral domain optical coherence tomography.

Results

The mean age of the patients was 59.1 years. Mean subfoveal choroidal thickness was 388 μm. FA revealed non-patognomic features including RPE alterations, window defects, leaking points and leakage from an undetermined source. ICGA revealed choroidal vascular plaque in eight eyes (42%) and suspicious plaque in five eyes (26%). Nonneovascular features, such as hyperpermeability or dilated choroidal vessels, were observed in six eyes (32%). OCTA showed choroidal neovascularization in 14 (74%). For all of the eyes, which ICGA was positive for presence of CNV, OCTA also showed CNV, and in one case it also revealed polypoidal characteristics of the neovascular network. OCTA was also able to detect CNV in all of the eyes with suspicious plaque, and in one eye without CNV appearance using ICGA.

Conclusions

OCTA demonstrated greater sensitivity in detecting type 1 CNV than conventional dye angiography in cases with pachychoroid spectrum disease.

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Title: The use of optical coherence tomography angiography in pachychoroid spectrum diseases: a concurrent comparison with dye angiography
Authors: Sibel Demirel
Özge Yanık
Hilal Nalcı
Figen Batıoğlu
Emin Özmert
Publication date: 01-12-2017
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2017
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-017-3793-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The use of optical coherence tomography angiography in pachychoroid spectrum diseases: a concurrent comparison with dye angiography

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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