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Critical Care
Published in: Critical Care 6/2008

01-12-2008 | Commentary

The severity of sepsis: yet another factor influencing glycemic control

Author: James S Krinsley

Published in: Critical Care | Issue 6/2008

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Abstract

The present commentary provides a brief overview of the evolving literature on glycemic management in critically ill patients. Recent interventional studies have been plagued by high rates of severe hypoglycemia among patients, particularly those with sepsis. The investigation by Waeschle and colleagues adds to our knowledge about the relationship between the severity of sepsis and glycemic dysregulation. The severity of sepsis is shown to correlate with the risk of sustaining hyperglycemia as well as critical hypoglycemia.
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Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R: Intensive insulin therapy in the critically ill patients. N Engl J Med 2001, 345: 1359-1367. 10.1056/NEJMoa011300CrossRefPubMed
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Krinsley JS: Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med 2008, 36: 3008-3013. 10.1097/CCM.0b013e31818b38d2CrossRefPubMed
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Metadata
Title
The severity of sepsis: yet another factor influencing glycemic control
Author
James S Krinsley
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2008
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc7111

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