Skip to main content
Top
Published in: European Spine Journal 12/2010

01-12-2010 | Original Article

The results of simultaneous posterior–anterior–posterior surgery in multilevel tuberculosis spondylitis associated with severe kyphosis

Authors: Erden Erturer, Mehmet Tezer, Mehmet Aydogan, Cunety Mirzanlı, İrfan Ozturk

Published in: European Spine Journal | Issue 12/2010

Login to get access

Abstract

We retrospectively studied the cases with tuberculous spondylitis of thoracolumbar region with two or more levels of involvement that underwent posterior instrumentation and fusion and anterior fusion with titanium mesh following anterior decompression using simultaneous successive posterior–anterior–posterior surgery. Among all patients with tuberculous spondylitis accompanied by medium or severe kyphosis, 20 patients who underwent simultaneous successive decompression, fusion and instrumentation with posterior–anterior–posterior surgery between 1999 and 2004 were included in the study. Patients were evaluated for fusion formation and neurological and functional status. Kyphosis angles were measured at early and long-term follow-up. Antituberculosis chemotherapy was initiated in all patients and continued for 9 months; initially as quadruple therapy for 3 months, and then as triple therapy. Average follow-up period was 52.7 months (range 37–94). Solid fusion was achieved in all patients. All patients returned to their previous occupation; 75% (15 subjects) with mild pain or no pain and 15% (3 subjects) with major limitations. There were 11 patients with neurological deficit, 9 of these achieved complete neurological recoveries. Regarding kyphosis angle, an average 35.1° correction (84.8%) was obtained in postoperative period (p < 0.001) and there was no significant correction loss during the follow-up period (p < 0.05). There were no grafts or instrumentation-related stabilization problems. In subjects with tuberculous spondylitis with involvements at two or more levels accompanied by medium and severe kyphosis, decompression, fusion and instrumentation by simultaneous successive posterior–anterior–posterior surgery is an effective and safe management method for effective kyphosis correction with high fusion rates.
Literature
1.
go back to reference Benli IT, Acaroglu E, Akalin S, Kis M, Duman E, Un A (2003) Anterior radical debridement and anterior instrumentation in tuberculosis spondylitis. Eur Spine J 12:224–234PubMed Benli IT, Acaroglu E, Akalin S, Kis M, Duman E, Un A (2003) Anterior radical debridement and anterior instrumentation in tuberculosis spondylitis. Eur Spine J 12:224–234PubMed
2.
go back to reference Chen WJ, Wu CC, Jung CH, Chen LH, Niu CC, Lai PL (2002) Combined anterior and posterior surgeries in the treatment of spinal tuberculous spondylitis. Clin Orthop Relat Res 398:50–59CrossRefPubMed Chen WJ, Wu CC, Jung CH, Chen LH, Niu CC, Lai PL (2002) Combined anterior and posterior surgeries in the treatment of spinal tuberculous spondylitis. Clin Orthop Relat Res 398:50–59CrossRefPubMed
3.
go back to reference Denis F, Armstrong GWD, Searls K, Matta L (1984) Acute thoracolumbar burst fractures in the absence of neurologic deficit a comparison between operative and nonoperative treatment. Clin Orthop Relat Res 189:125–141 Denis F, Armstrong GWD, Searls K, Matta L (1984) Acute thoracolumbar burst fractures in the absence of neurologic deficit a comparison between operative and nonoperative treatment. Clin Orthop Relat Res 189:125–141
4.
go back to reference Dvorak MF, Kwon BK, Fisher CG, Eiserloh HL 3rd, Boyd M, Wing PC (2003) Effectiveness of titanium mesh cylindrical cages in anterior column reconstruction after thoracic and lumbar vertebral body resection. Spine 28:902–908CrossRefPubMed Dvorak MF, Kwon BK, Fisher CG, Eiserloh HL 3rd, Boyd M, Wing PC (2003) Effectiveness of titanium mesh cylindrical cages in anterior column reconstruction after thoracic and lumbar vertebral body resection. Spine 28:902–908CrossRefPubMed
5.
go back to reference Eck KR, Bridwell KH, Ungacta FF, Lapp MA, Lenke LG, Riew KD (2000) Analysis of titanium mesh cages in adults with minimum two-year follow-up. Spine 25:2407–2415CrossRefPubMed Eck KR, Bridwell KH, Ungacta FF, Lapp MA, Lenke LG, Riew KD (2000) Analysis of titanium mesh cages in adults with minimum two-year follow-up. Spine 25:2407–2415CrossRefPubMed
6.
go back to reference Faraj AA (2001) Anterior instrumentation for the treatment of spinal tuberculosis. J Bone Jt Surg (Am) 83:463–464 Faraj AA (2001) Anterior instrumentation for the treatment of spinal tuberculosis. J Bone Jt Surg (Am) 83:463–464
7.
go back to reference Frankel HL, Hancock DO, Hyskop G (1969) The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. Paraplegia 7:179–192PubMed Frankel HL, Hancock DO, Hyskop G (1969) The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. Paraplegia 7:179–192PubMed
8.
go back to reference Fukuta S, Miyamoto K, Masuda T, Hosoe H, Kodama H, Nishimoto H, Sakaeda H, Shimizu K (2003) Two-stage (posterior and anterior) surgical treatment using posterior spinal instrumentation for pyogenic and tuberculotic spondylitis. Spine 28:302–308CrossRef Fukuta S, Miyamoto K, Masuda T, Hosoe H, Kodama H, Nishimoto H, Sakaeda H, Shimizu K (2003) Two-stage (posterior and anterior) surgical treatment using posterior spinal instrumentation for pyogenic and tuberculotic spondylitis. Spine 28:302–308CrossRef
9.
go back to reference Hamzaoğlu A (1999) Granulomatous infection of the spine. In: Floman Y (ed) State of the art reviews, spinal infections. Hanley and Belfus, Philadelphia, pp 45–78 Hamzaoğlu A (1999) Granulomatous infection of the spine. In: Floman Y (ed) State of the art reviews, spinal infections. Hanley and Belfus, Philadelphia, pp 45–78
10.
go back to reference Hee HT, Majd ME, Holt RT, Pienkowski D (2002) Better treatment of vertebral osteomyelitis using posterior stabilization and titanium mesh cages. J Spinal Disord Tech 15:149–156PubMed Hee HT, Majd ME, Holt RT, Pienkowski D (2002) Better treatment of vertebral osteomyelitis using posterior stabilization and titanium mesh cages. J Spinal Disord Tech 15:149–156PubMed
11.
go back to reference Hilibrand AS, Quartararo LG, Moulton MRJ (2003) Spinal infections. In: Koval KJ (ed) Orthopaedic knowledge uptake 7. American Academy of Orthopaedic Surgeons, pp 661–672 Hilibrand AS, Quartararo LG, Moulton MRJ (2003) Spinal infections. In: Koval KJ (ed) Orthopaedic knowledge uptake 7. American Academy of Orthopaedic Surgeons, pp 661–672
12.
go back to reference Hodgson AR, Stock FE (1994) Anterior spinal fusion: preliminary communication on radical treatment of Pott’s disease and Pott’s paraplegia. Clin Orthop Relat Res 300:16–23PubMed Hodgson AR, Stock FE (1994) Anterior spinal fusion: preliminary communication on radical treatment of Pott’s disease and Pott’s paraplegia. Clin Orthop Relat Res 300:16–23PubMed
13.
go back to reference Janssens JP, de Haller R (1990) Spinal tuberculosis in a developed country. A review of 26 cases with special emphasis on abscesses and neurologic complications. Clin Orthop Relat Res 257:67–75PubMed Janssens JP, de Haller R (1990) Spinal tuberculosis in a developed country. A review of 26 cases with special emphasis on abscesses and neurologic complications. Clin Orthop Relat Res 257:67–75PubMed
14.
go back to reference Jin D, Qu D, Chen J, Zhang H (2004) One-stage anterior interbody autografting and instrumentation in primary surgical management of thoracolumbar spinal tuberculosis. Eur Spine J 13:114–121CrossRefPubMed Jin D, Qu D, Chen J, Zhang H (2004) One-stage anterior interbody autografting and instrumentation in primary surgical management of thoracolumbar spinal tuberculosis. Eur Spine J 13:114–121CrossRefPubMed
15.
go back to reference Kim DJ, Yun YH, Moon SH, Riew KD (2004) Posterior instrumentation using compressive laminar hooks and anterior interbody arthrodesis for the treatment of tuberculosis of the lower lumbar spine. Spine 29:275–279CrossRef Kim DJ, Yun YH, Moon SH, Riew KD (2004) Posterior instrumentation using compressive laminar hooks and anterior interbody arthrodesis for the treatment of tuberculosis of the lower lumbar spine. Spine 29:275–279CrossRef
16.
go back to reference Klockner C, Valencia R (2003) Sagittal alignment after anterior debridement and fusion with or without additional posterior instrumentation in the treatment of pyogenic and tuberculous spondylodiscitis. Spine 15:1036–1042CrossRef Klockner C, Valencia R (2003) Sagittal alignment after anterior debridement and fusion with or without additional posterior instrumentation in the treatment of pyogenic and tuberculous spondylodiscitis. Spine 15:1036–1042CrossRef
17.
go back to reference Laheri VJ, Badhe NP, Dewnany GT (2001) Single stage decompression, anterior interbody fusion and posterior instrumentation for tuberculous kyphosis of the dorso-lumbar spine. Spinal Cord 39:429–436CrossRefPubMed Laheri VJ, Badhe NP, Dewnany GT (2001) Single stage decompression, anterior interbody fusion and posterior instrumentation for tuberculous kyphosis of the dorso-lumbar spine. Spinal Cord 39:429–436CrossRefPubMed
18.
go back to reference Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12:606–612CrossRefPubMed Liljenqvist U, Lerner T, Bullmann V, Hackenberg L, Halm H, Winkelmann W (2003) Titanium cages in the surgical treatment of severe vertebral osteomyelitis. Eur Spine J 12:606–612CrossRefPubMed
20.
go back to reference Medical Research Council Working Party On Tuberculosis of the Spine (1982) A 10-year assessments of controlled trials comparing debridement and anterior spinal fusion in the management of tuberculosis of the spine in patients on standard chemotherapy in Hong-Kong. J Bone Jt Surg (Br) 64:393–398 Medical Research Council Working Party On Tuberculosis of the Spine (1982) A 10-year assessments of controlled trials comparing debridement and anterior spinal fusion in the management of tuberculosis of the spine in patients on standard chemotherapy in Hong-Kong. J Bone Jt Surg (Br) 64:393–398
21.
go back to reference Moon MS, Moon YW, Moon JL, Kim SS, Sun DH (2002) Conservative treatment of tuberculosis of the lumbar and lumbosacral spine. Clin Orthop Relat Res 398:40–49CrossRefPubMed Moon MS, Moon YW, Moon JL, Kim SS, Sun DH (2002) Conservative treatment of tuberculosis of the lumbar and lumbosacral spine. Clin Orthop Relat Res 398:40–49CrossRefPubMed
22.
go back to reference Moon MS, Woo YK, Lee KS et al (1995) Posterior instrumentation and anterior interbody fusion for tuberculous kyphosis of dorsal and lumbar spine. Spine 20:1910–1916CrossRefPubMed Moon MS, Woo YK, Lee KS et al (1995) Posterior instrumentation and anterior interbody fusion for tuberculous kyphosis of dorsal and lumbar spine. Spine 20:1910–1916CrossRefPubMed
23.
go back to reference Moon MS (1997) Spine update. Tuberculosis of the spine: controversies and new challenge. Spine 22:1791–1797CrossRefPubMed Moon MS (1997) Spine update. Tuberculosis of the spine: controversies and new challenge. Spine 22:1791–1797CrossRefPubMed
24.
go back to reference Oga M, Arizono T, Takasita M, Sugioka Y (1993) Evaluation of the risk of instrumentation as a foreign body in spinal tuberculosis. Clinical and biologic study. Spine 18:1890–1894CrossRefPubMed Oga M, Arizono T, Takasita M, Sugioka Y (1993) Evaluation of the risk of instrumentation as a foreign body in spinal tuberculosis. Clinical and biologic study. Spine 18:1890–1894CrossRefPubMed
25.
go back to reference Ozdemir M, Us K, Ogun T (2003) The role of anterior spinal instrumentation and allograft fibula for treatment of Pott disease. Spine 28:474–479CrossRefPubMed Ozdemir M, Us K, Ogun T (2003) The role of anterior spinal instrumentation and allograft fibula for treatment of Pott disease. Spine 28:474–479CrossRefPubMed
26.
go back to reference Rajasekaran S, Soundarapandian S (1989) Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis. J Bone Jt Surg (Am) 71:1314–1323 Rajasekaran S, Soundarapandian S (1989) Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis. J Bone Jt Surg (Am) 71:1314–1323
27.
go back to reference Robertson PA, Rawlinson HJ, Hadlow AT (2004) Radiologic stability of titanium mesh cages for anterior spinal reconstruction following thoracolumbar corpectomy. J Spinal Disord Tech. 17:44–52CrossRefPubMed Robertson PA, Rawlinson HJ, Hadlow AT (2004) Radiologic stability of titanium mesh cages for anterior spinal reconstruction following thoracolumbar corpectomy. J Spinal Disord Tech. 17:44–52CrossRefPubMed
28.
go back to reference Safran O, Rand N, Kaplan L, Sagiv S, Floman Y (1998) Sequential or simultaneous, same-day anterior decompression and posterior stabilization in the management of vertebral osteomyelitis of the lumbar spine. Spine 23:1885–1890CrossRefPubMed Safran O, Rand N, Kaplan L, Sagiv S, Floman Y (1998) Sequential or simultaneous, same-day anterior decompression and posterior stabilization in the management of vertebral osteomyelitis of the lumbar spine. Spine 23:1885–1890CrossRefPubMed
29.
go back to reference Sundararaj GD, Behera S, Ravi V, Venkatesh K, Cherian VM, Lee V (2003) Role of posterior stabilisation in the management of tuberculosis of the dorsal and lumbar spine. J Bone Jt Surg (Br) 85:100–106CrossRef Sundararaj GD, Behera S, Ravi V, Venkatesh K, Cherian VM, Lee V (2003) Role of posterior stabilisation in the management of tuberculosis of the dorsal and lumbar spine. J Bone Jt Surg (Br) 85:100–106CrossRef
30.
go back to reference Thirteenth Report Of The Medical Research Council Working Party On Tuberculosis Of The Spine (1998) A 15-year assessment of controlled trials of the management of tuberculosis of the spine in Korea and Hong Kong. J Bone Jt Surg (Br) 80:456–462CrossRef Thirteenth Report Of The Medical Research Council Working Party On Tuberculosis Of The Spine (1998) A 15-year assessment of controlled trials of the management of tuberculosis of the spine in Korea and Hong Kong. J Bone Jt Surg (Br) 80:456–462CrossRef
31.
go back to reference Wen-Jer C, Chi-Chuan W, Chi-Hsiung J (2002) Combined anterior and posterior surgeries in the treatment of tuberculous spondylitis. Clin Orthop Relat Res 398:50–59CrossRef Wen-Jer C, Chi-Chuan W, Chi-Hsiung J (2002) Combined anterior and posterior surgeries in the treatment of tuberculous spondylitis. Clin Orthop Relat Res 398:50–59CrossRef
32.
go back to reference Wimmer C, Ogon M, Sterzinger W, Landauer F, Stockl B (1997) Conservative treatment of tuberculous spondylitis: a long-term follow-up study. J Spinal Disord 10:417–419CrossRefPubMed Wimmer C, Ogon M, Sterzinger W, Landauer F, Stockl B (1997) Conservative treatment of tuberculous spondylitis: a long-term follow-up study. J Spinal Disord 10:417–419CrossRefPubMed
33.
go back to reference Yilmaz C, Selek HY, Gurkan I, Erdemli B, Korkusuz Z (1999) Anterior instrumentation for the treatment of spinal tuberculosis. J Bone Jt Surg (Am) 81:1261–1267 Yilmaz C, Selek HY, Gurkan I, Erdemli B, Korkusuz Z (1999) Anterior instrumentation for the treatment of spinal tuberculosis. J Bone Jt Surg (Am) 81:1261–1267
Metadata
Title
The results of simultaneous posterior–anterior–posterior surgery in multilevel tuberculosis spondylitis associated with severe kyphosis
Authors
Erden Erturer
Mehmet Tezer
Mehmet Aydogan
Cunety Mirzanlı
İrfan Ozturk
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 12/2010
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-010-1481-z

Other articles of this Issue 12/2010

European Spine Journal 12/2010 Go to the issue