Skip to main content
Top
Published in: Sleep and Breathing 3/2013

01-09-2013 | Original Article

The prevalence and associated risk factors of sleep disorder-related symptoms in pregnant women in China

Authors: Xiao-Hong Cai, Yu-Peng Xie, Xiu-Cui Li, Wang-Lei Qu, Ting Li, Hong-Xia Wang, Jie-Qiang Lv, Liang-Xing Wang

Published in: Sleep and Breathing | Issue 3/2013

Login to get access

Abstract

Purpose

The sleep disorder in pregnant women remains unfamiliar to perinatal care providers, resulting in lack of appropriate care. This study was designed to investigate the prevalence of sleep disorder-related symptoms in pregnant women and to identify the associated risk factors.

Methods

Married pregnant women were enrolled from their first trimester and followed up until delivery. Nonpregnant married healthy women were selected as controls. A survey questionnaire was administered to each of them.

Results

We successfully performed a survey to 1,993 pregnant women and 598 nonpregnant women. The overall prevalence of sleep disorder-related symptoms in pregnant women was significantly higher than the controls (56.1 vs. 29.9 %, P < 0.05). There was higher prevalence of snoring (30.2 %), observed sleep apnea (1.1 %), mouth breathing (23.7 %), nocturnal arousal (46.5 %), insomnia (35.1 %), and daytime sleepiness (52.6 %) in pregnant women. There were no significant differences of the prevalence of bruxism (7.0 vs. 6.7 %), sleep talking (8.1 vs. 7.2 %), and sleep walking (0.4 vs. 0.2 %) between the two groups (P > 0.05). Nocturnal sleep time (8.0 ± 1.3 h) was less in the third trimester compared with the nonpregnant women (8.2 ± 1.1 h) (P < 0.05). Smoking (OR = 3.39), drinking (OR = 2.40), allergic rhinitis/asthma (OR = 1.71), an obvious difference in neck circumference (OR = 1.11), and waistline (OR = 1.07) changes between the first and third trimesters were the risk factors for sleep disorder-related problems.

Conclusions

There is a high prevalence of sleep disorder-related symptoms in pregnant women. Our data may provide a baseline for prevention and treatment of sleep disturbances in pregnant women.
Literature
1.
go back to reference American Academy of Sleep Medicine (2001) International classification of sleep disorders, revised: diagnostic and coding manual. American Academy of Sleep Medicine, Chicago, Illinois American Academy of Sleep Medicine (2001) International classification of sleep disorders, revised: diagnostic and coding manual. American Academy of Sleep Medicine, Chicago, Illinois
2.
go back to reference Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E (2005) Sleep loss: a novel risk factor for insulin resistance and type 2 diabetes. J Appl Physiol 99(5):2008–2019PubMedCrossRef Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E (2005) Sleep loss: a novel risk factor for insulin resistance and type 2 diabetes. J Appl Physiol 99(5):2008–2019PubMedCrossRef
3.
go back to reference Quercioli A, Mach F, Montecucco F (2010) Inflammation accelerates atherosclerotic processes in obstructive sleep apnea syndrome (OSAS). Sleep Breath 14(3):261–269PubMedCrossRef Quercioli A, Mach F, Montecucco F (2010) Inflammation accelerates atherosclerotic processes in obstructive sleep apnea syndrome (OSAS). Sleep Breath 14(3):261–269PubMedCrossRef
4.
go back to reference Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP (1999) Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med 131(7):485–491PubMedCrossRef Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP (1999) Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med 131(7):485–491PubMedCrossRef
5.
go back to reference Aloba OO, Adewuya AO, Ola BA, Mapayi BM (2007) Validity of the Pittsburgh Sleep Quality Index (PSQI) among Nigerian university students. Sleep Med 8(3):266–270PubMedCrossRef Aloba OO, Adewuya AO, Ola BA, Mapayi BM (2007) Validity of the Pittsburgh Sleep Quality Index (PSQI) among Nigerian university students. Sleep Med 8(3):266–270PubMedCrossRef
6.
go back to reference Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14(6):540–545PubMed Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14(6):540–545PubMed
7.
go back to reference Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, Benjamin A, Kimoff RJ (2009) Obstructive sleep apnoea and its association with gestational hypertension. Eur Respir J 33(3):559–565PubMedCrossRef Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, Benjamin A, Kimoff RJ (2009) Obstructive sleep apnoea and its association with gestational hypertension. Eur Respir J 33(3):559–565PubMedCrossRef
8.
go back to reference Venkata C, Venkateshiah SB (2009) Sleep-disordered breathing during pregnancy. J Am Board Fam Med: JABFM 22(2):158–168PubMedCrossRef Venkata C, Venkateshiah SB (2009) Sleep-disordered breathing during pregnancy. J Am Board Fam Med: JABFM 22(2):158–168PubMedCrossRef
9.
go back to reference Mindell JA, Jacobson BJ (2000) Sleep disturbances during pregnancy. J Obstet Gynecol Neonatal Nurs 29(6):590–597PubMedCrossRef Mindell JA, Jacobson BJ (2000) Sleep disturbances during pregnancy. J Obstet Gynecol Neonatal Nurs 29(6):590–597PubMedCrossRef
10.
go back to reference Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ (2005) Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep 28(10):1299–1305PubMed Pien GW, Fife D, Pack AI, Nkwuo JE, Schwab RJ (2005) Changes in symptoms of sleep-disordered breathing during pregnancy. Sleep 28(10):1299–1305PubMed
11.
go back to reference Izci B, Vennelle M, Liston WA, Dundas KC, Calder AA, Douglas NJ (2006) Sleep-disordered breathing and upper airway size in pregnancy and post-partum. Eur Respir J 27(2):321–327PubMedCrossRef Izci B, Vennelle M, Liston WA, Dundas KC, Calder AA, Douglas NJ (2006) Sleep-disordered breathing and upper airway size in pregnancy and post-partum. Eur Respir J 27(2):321–327PubMedCrossRef
12.
go back to reference Roush SF, Bell L (2004) Obstructive sleep apnea in pregnancy. J Am Board Fam Pract/Am Board Fam Pract 17(4):292–294CrossRef Roush SF, Bell L (2004) Obstructive sleep apnea in pregnancy. J Am Board Fam Pract/Am Board Fam Pract 17(4):292–294CrossRef
13.
go back to reference Weinberger SE, Weiss ST, Cohen WR, Weiss JW, Johnson TS (1980) Pregnancy and the lung. Am Rev Respir Dis 121(3):559–581PubMed Weinberger SE, Weiss ST, Cohen WR, Weiss JW, Johnson TS (1980) Pregnancy and the lung. Am Rev Respir Dis 121(3):559–581PubMed
14.
go back to reference Jensen D, Duffin J, Lam YM, Webb KA, Simpson JA, Davies GA, Wolfe LA, O’Donnell DE (2008) Physiological mechanisms of hyperventilation during human pregnancy. Respir Physiol Neurobiol 161(1):76–86PubMedCrossRef Jensen D, Duffin J, Lam YM, Webb KA, Simpson JA, Davies GA, Wolfe LA, O’Donnell DE (2008) Physiological mechanisms of hyperventilation during human pregnancy. Respir Physiol Neurobiol 161(1):76–86PubMedCrossRef
15.
16.
go back to reference Nielsen T, Paquette T (2007) Dream-associated behaviors affecting pregnant and postpartum women. Sleep 30(9):1162–1169PubMed Nielsen T, Paquette T (2007) Dream-associated behaviors affecting pregnant and postpartum women. Sleep 30(9):1162–1169PubMed
17.
go back to reference Nakamura M, Aoki N, Nakashima T, Hoshino T, Yokoyama T, Morioka S, Kawamura T, Tanaka H, Hashimoto T, Ohno Y, Whitlock G (2001) Smoking, alcohol, sleep and risk of idiopathic sudden deafness: a case–control study using pooled controls. J epidemiol/Jpn Epidemiol Assoc 11(2):81–86CrossRef Nakamura M, Aoki N, Nakashima T, Hoshino T, Yokoyama T, Morioka S, Kawamura T, Tanaka H, Hashimoto T, Ohno Y, Whitlock G (2001) Smoking, alcohol, sleep and risk of idiopathic sudden deafness: a case–control study using pooled controls. J epidemiol/Jpn Epidemiol Assoc 11(2):81–86CrossRef
18.
go back to reference Casasola GG, Alvarez-Sala JL, Marques JA, Sanchez-Alarcos JM, Tashkin DP, Espinos D (2002) Cigarette smoking behavior and respiratory alterations during sleep in a healthy population. Sleep Breath 6(1):19–24PubMedCrossRef Casasola GG, Alvarez-Sala JL, Marques JA, Sanchez-Alarcos JM, Tashkin DP, Espinos D (2002) Cigarette smoking behavior and respiratory alterations during sleep in a healthy population. Sleep Breath 6(1):19–24PubMedCrossRef
19.
go back to reference Bonnin-Vilaplana M, Arboix A, Parra O, Garcia-Eroles L, Montserrat JM, Massons J (2009) Sleep-related breathing disorders in acute lacunar stroke. J Neurol 256(12):2036–2042PubMedCrossRef Bonnin-Vilaplana M, Arboix A, Parra O, Garcia-Eroles L, Montserrat JM, Massons J (2009) Sleep-related breathing disorders in acute lacunar stroke. J Neurol 256(12):2036–2042PubMedCrossRef
20.
go back to reference Schunemann HJ, Grant BJ, Freudenheim JL, Muti P, McCann SE, Kudalkar D, Ram M, Nochajski T, Russell M, Trevisan M (2002) Evidence for a positive association between pulmonary function and wine intake in a population-based study. Sleep Breath 6(4):161–173PubMedCrossRef Schunemann HJ, Grant BJ, Freudenheim JL, Muti P, McCann SE, Kudalkar D, Ram M, Nochajski T, Russell M, Trevisan M (2002) Evidence for a positive association between pulmonary function and wine intake in a population-based study. Sleep Breath 6(4):161–173PubMedCrossRef
21.
go back to reference Roehrs T, Roth T (2001) Sleep, sleepiness, and alcohol use. Alcohol res health: j Natl Inst Alcohol Abuse Alcohol 25(2):101–109 Roehrs T, Roth T (2001) Sleep, sleepiness, and alcohol use. Alcohol res health: j Natl Inst Alcohol Abuse Alcohol 25(2):101–109
22.
go back to reference Guilleminault C, Querra-Salva M, Chowdhuri S, Poyares D (2000) Normal pregnancy, daytime sleeping, snoring and blood pressure. Sleep Med 1(4):289–297PubMedCrossRef Guilleminault C, Querra-Salva M, Chowdhuri S, Poyares D (2000) Normal pregnancy, daytime sleeping, snoring and blood pressure. Sleep Med 1(4):289–297PubMedCrossRef
23.
go back to reference Bucca C, Brussino L, Maule MM, Baldi I, Guida G, Culla B, Merletti F, Foresi A, Rolla G, Mutani R, Cicolin A (2011) Clinical and functional prediction of moderate to severe obstructive sleep apnoea. Clin Respir J 5(4):219–226PubMedCrossRef Bucca C, Brussino L, Maule MM, Baldi I, Guida G, Culla B, Merletti F, Foresi A, Rolla G, Mutani R, Cicolin A (2011) Clinical and functional prediction of moderate to severe obstructive sleep apnoea. Clin Respir J 5(4):219–226PubMedCrossRef
Metadata
Title
The prevalence and associated risk factors of sleep disorder-related symptoms in pregnant women in China
Authors
Xiao-Hong Cai
Yu-Peng Xie
Xiu-Cui Li
Wang-Lei Qu
Ting Li
Hong-Xia Wang
Jie-Qiang Lv
Liang-Xing Wang
Publication date
01-09-2013
Publisher
Springer Berlin Heidelberg
Published in
Sleep and Breathing / Issue 3/2013
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-012-0783-2

Other articles of this Issue 3/2013

Sleep and Breathing 3/2013 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine