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Clinical Reviews in Allergy & Immunology

Published in:

01-06-2008

The Predictive Significance of Autoantibodies in Organ-Specific Autoimmune Diseases

Author: Nicola Bizzaro

Published in: Clinical Reviews in Allergy & Immunology | Issue 3/2008

Abstract

Many organ-specific autoimmune diseases are preceded by a long pre-clinical phase, and several longitudinal cohort studies have shown that patients may carry autoantibodies many years before they manifest clinical symptoms. Detecting these antibodies in serum has been shown to have strong predictive value, depending on the particular autoantibody, test method, and disease at issue. This review examines the predictive value of various autoantibodies that are found in organ-specific autoimmune diseases, such as primary biliary cirrhosis, Addison’s disease, Hashimoto’s thyroiditis, type-1 diabetes, celiac disease, and Crohn’s disease.

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Title: The Predictive Significance of Autoantibodies in Organ-Specific Autoimmune Diseases
Author: Nicola Bizzaro
Publication date: 01-06-2008
Publisher: Humana Press Inc
Published in: Clinical Reviews in Allergy & Immunology / Issue 3/2008
Print ISSN: 1080-0549
Electronic ISSN: 1559-0267
DOI: https://doi.org/10.1007/s12016-007-8059-5

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