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Published in: Molecular Imaging and Biology 6/2010

01-12-2010 | Review Article

The Labeled-Leukocyte Scan in the Study of Abdominal Abscesses

Authors: Mauro Liberatore, Enrico Calandri, Gabriele Ciccariello, Marzia Fioravanti, Valentina Megna, Lucia Rampin, Maria Cristina Marzola, Imene Zerizer, Adil Al-Nahhas, Domenico Rubello

Published in: Molecular Imaging and Biology | Issue 6/2010

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Abstract

Aim

The purpose of the present paper was to review the literature over the last 30 years to assess the value of radionuclide imaging, particularly labeled leukocyte scan, as compared to other imaging modalities in the management of abdominal abscesses.

Methods

A systematic review of the published studies in humans cited in PubMed written in English, French, German, Italian, and Spanish was made.

Results

Ultrasound (US) has lower sensitivity than leukocyte scan (LS), particularly in patients without localizing signs, while CT has higher sensitivity than US, but less than LS. On the other hand, CT had higher specificity than both LS and US.

Discussion

LS is the more sensitive method to localize abdominal abscesses and may guide dedicated US and CT investigations to improve their diagnostic potential. Further diagnostic evolution is expected from the routine use of hybrid SPECT/CT systems.
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Metadata
Title
The Labeled-Leukocyte Scan in the Study of Abdominal Abscesses
Authors
Mauro Liberatore
Enrico Calandri
Gabriele Ciccariello
Marzia Fioravanti
Valentina Megna
Lucia Rampin
Maria Cristina Marzola
Imene Zerizer
Adil Al-Nahhas
Domenico Rubello
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Molecular Imaging and Biology / Issue 6/2010
Print ISSN: 1536-1632
Electronic ISSN: 1860-2002
DOI
https://doi.org/10.1007/s11307-010-0314-0

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