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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 4/2016

01-12-2016 | Review Article

The Interaction Between Niche and Hematopoietic Stem Cells

Authors: Chaoyu Wang, Chen Tian, Yizhuo Zhang

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 4/2016

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Abstract

Hematopoietic stem cells (HSCs) are one of the somatic stem cells that have the ability to regenerate the entire blood system in a hierarchical way for the duration of an adult life. HSCs reside in the bone marrow niche which contain different cells and molecules that regulate the balance of HSC dormancy and activation. Here, we describe the interaction between HSCs and their niche, in particularly the involvement of some signaling pathway. Insights into the hematopoietic microenvironment will help to obtain a better understanding of normal hematopoiesis and how environmental factors affect these processes.
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Metadata
Title
The Interaction Between Niche and Hematopoietic Stem Cells
Authors
Chaoyu Wang
Chen Tian
Yizhuo Zhang
Publication date
01-12-2016
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue 4/2016
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-016-0639-1

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