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01-01-2018 | Commentary

The Implications of Genetics for Prevention and Intervention Programming

Authors: Rashelle J. Musci, Gabriel Schlomer

Published in: Prevention Science | Issue 1/2018

Excerpt

With recent advances in high-throughput technology, genetic and other biological data have been increasingly incorporated in social science research, including prevention/intervention studies. Understanding the role genetics play in complex behaviors commonly evaluated in prevention/intervention research may have important implications for designing prevention programing, determining who receives certain prevention programs, and understanding individual differences in programming effectiveness (see Jaffee and Price 2007; Moffitt et al. 2006). This special issue, Incorporating Genetics in Prevention Science: Considering Methodology and Implications, seeks to advance work in this area by presenting empirical research and methodological reviews that examine the role genetics has in behavioral research. This special issue highlights the strengths, challenges, and methodological approaches that can be used to incorporate genetic and other biological data (e.g., epigenetic markers) into prevention science. The papers in this special issue cover several overarching themes that have emerged as critical for adequately incorporating genetics into prevention and other behavioral research, including gene-by-intervention (GxI) studies. The collection of papers reflect examples, suggestions, opportunities, and pitfalls (and how to avoid them) when incorporating genetics or other biological data into prevention research. Below, we highlight some of the themes and strengths of GxI research as reflected in the set of studies included in this special issue. …

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Musci, R. J., Fairman, B., Masyn, K. E., Uhl, G., Maher, B., Sisto, D. Y., et al. (2017). Polygenic score × intervention moderation: An application of discrete-time survival analysis to model the timing of first marijuana use among urban youth. Prevention Science. https://doi.org/10.1007/s11121-016-0729-1.

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Title: The Implications of Genetics for Prevention and Intervention Programming
Authors: Rashelle J. Musci
Gabriel Schlomer
Publication date: 01-01-2018
Publisher: Springer US
Published in: Prevention Science / Issue 1/2018
Print ISSN: 1389-4986
Electronic ISSN: 1573-6695
DOI: https://doi.org/10.1007/s11121-017-0837-6

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Other articles of this Issue 1/2018

Commentary for Special Issue of Prevention Science “Using Genetics in Prevention: Science Fiction or Science Fact?”

Glucocorticoid Receptor (NR3C1) Gene Polymorphism Moderate Intervention Effects on the Developmental Trajectory of African-American Adolescent Alcohol Abuse

Polygenic Score × Intervention Moderation: an Application of Discrete-Time Survival Analysis to Model the Timing of First Marijuana Use Among Urban Youth

PROSPER Intervention Effects on Adolescents’ Alcohol Misuse Vary by GABRA2 Genotype and Age

Critical Issues in the Inclusion of Genetic and Epigenetic Information in Prevention and Intervention Trials

Naturalistic Experimental Designs as Tools for Understanding the Role of Genes and the Environment in Prevention Research