Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Journal of Neuro-Oncology
Published in: Journal of Neuro-Oncology 1/2017

01-05-2017 | Letter to the Editor

The growing role of biology in the treatment of glioblastoma: no more one kind of disease

Authors: Michela Buglione, Luca Triggiani, Stefano Maria Magrini

Published in: Journal of Neuro-Oncology | Issue 1/2017

Login to get access

Excerpt

To the Editor, …
Literature
1.
Buglione M, Pedretti S, Poliani PL, Liserre R, Gipponi S, Spena G, Borghetti P, Pegurri L, Saiani F, Spiazzi L, Tesini G, Uccelli C, Trigiani L, Magrini SM (2016) Pattern of relapse of glioblastoma multiforme treated with radical radio-chemotherapy: could a margin reduction be proposed? J Neurooncol 128(2):303–312CrossRefPubMed
2.
Verhaak RGW, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O’Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS et al (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98–110CrossRefPubMedPubMedCentral
3.
Tini P, Pastina P, Nardone V, Sebaste L, Toscano M, Miracco C, Cerase A, Pirtoli L (2016) The combined EGFR protein expression analysis refines the prognostic value of the MGMT promoter methylation status in glioblastoma. Clin Neurol Neurosurg 18(149):15–21CrossRef
4.
Cominelli M, Grisanti S, Mazzoleni S, Branca C, Buttolo L, Furlan D, Liserre B, Bonetti MF, Medicina D, Pellegrini V, Buglione M et al (2015) EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide. J Natl Cancer Inst. doi:10.​1093/​jnci/​djv041 PubMed
Metadata
Title
The growing role of biology in the treatment of glioblastoma: no more one kind of disease
Authors
Michela Buglione
Luca Triggiani
Stefano Maria Magrini
Publication date
01-05-2017
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 1/2017
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-017-2417-9

Other articles of this Issue 1/2017

Journal of Neuro-Oncology 1/2017 Go to the issue

Clinical Study

Cerebrospinal fluid dissemination of high-grade gliomas following boron neutron capture therapy occurs more frequently in the small cell subtype of IDH1R132H mutation-negative glioblastoma

Laboratory Investigation

Radiogenomics of lower-grade glioma: algorithmically-assessed tumor shape is associated with tumor genomic subtypes and patient outcomes in a multi-institutional study with The Cancer Genome Atlas data

Clinical Study

Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis

Clinical Study

Single fraction spine stereotactic ablative body radiotherapy with volumetric modulated arc therapy

Laboratory Investigation

Incidence and survival trends in oligodendrogliomas and anaplastic oligodendrogliomas in the United States from 2000 to 2013: a CBTRUS Report

Clinical Study

Does early resection of presumed low-grade glioma improve survival? A clinical perspective