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Surgical Endoscopy
Published in: Surgical Endoscopy 1/2014

01-01-2014 | New Technology

The feasibility of delivering a duodenal–jejunal bypass liner (endobarrier) endoscopically with patients under conscious sedation

Authors: Parviez Koehestanie, Bark Betzel, Kemal Dogan, Frits Berends, Ignace Janssen, Edo Aarts, Marcel Groenen, Peter Wahab

Published in: Surgical Endoscopy | Issue 1/2014

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Abstract

Background

The endoscopically placed duodenal–jejunal bypass liner (DJBL) or EndoBarrier gastrointestinal liner has been designed for the treatment of type 2 diabetes mellitus and simultaneous achievement of weight loss by obese patients. This study was performed to determine the safety, efficacy, and feasibility of delivering the DJBL with the patient under conscious sedation (CS). The primary end points of the study were safety and complications. The secondary end points were delivery time (min), amount of propofol (mg) used, and the total hospital stay (h).

Methods

This prospective study compared placement of the DJBL with the patient under propofol sedation and placement with the patient under general anesthesia (GA). The study included 56 patients, with 28 patients in each group.

Results

Both groups were comparable in terms of age, gender, and body mass index. All the devices were placed successfully, and no complications occurred in either group. Comparison of the CS group with the GA group respectively showed a mean total operation time of 29 versus 56 min, a mean propofol use of 170 versus 258 mg, and a mean hospital stay of 11 versus 22 h.

Conclusion

Delivery of the DJBL to patients under CS is feasible, safe, and efficient in terms of time and cost. Because of possible complications during the procedure, the authors recommend placement of the DJBL with the patient under CS in proximity to the operating room.
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Metadata
Title
The feasibility of delivering a duodenal–jejunal bypass liner (endobarrier) endoscopically with patients under conscious sedation
Authors
Parviez Koehestanie
Bark Betzel
Kemal Dogan
Frits Berends
Ignace Janssen
Edo Aarts
Marcel Groenen
Peter Wahab
Publication date
01-01-2014
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 1/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-013-3143-9

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