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Published in: Current Neurology and Neuroscience Reports 11/2013

01-11-2013 | Neuroimaging (DJ Brooks, Section Editor)

The Evolving Role of Diffusion Magnetic Resonance Imaging in Movement Disorders

Authors: Christopher W. Hess, Edward Ofori, Umer Akbar, Michael S. Okun, David E. Vaillancourt

Published in: Current Neurology and Neuroscience Reports | Issue 11/2013

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Abstract

Significant advances have allowed diffusion magnetic resonance imaging (MRI) to evolve into a powerful tool in the field of movement disorders that can be used to study disease states and connectivity between brain regions. Diffusion MRI is a promising potential biomarker for Parkinson’s disease and other forms of parkinsonism, and may allow the distinction of different forms of parkinsonism. Techniques such as tractography have contributed to our current thinking regarding the pathophysiology of dystonia and possible mechanisms of penetrance. Diffusion MRI measures could potentially assist in monitoring disease progression in Huntington’s disease, and in uncovering the nature of the processes and structures involved the development of essential tremor. The ability to represent structural connectivity in vivo also makes diffusion MRI an ideal adjunctive tool for the surgical treatment of movement disorders. We review recent studies using diffusion MRI in movement disorders research and present the current state of the science as well as future directions.
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Metadata
Title
The Evolving Role of Diffusion Magnetic Resonance Imaging in Movement Disorders
Authors
Christopher W. Hess
Edward Ofori
Umer Akbar
Michael S. Okun
David E. Vaillancourt
Publication date
01-11-2013
Publisher
Springer US
Published in
Current Neurology and Neuroscience Reports / Issue 11/2013
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-013-0400-1

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