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Langenbeck's Archives of Surgery
Published in: Langenbeck's Archives of Surgery 6/2012

01-08-2012 | Original Article

The evaluation of surgical treatment for gastric cancer patients with noncurative resection

Authors: Teiji Naka, Makoto Iwahashi, Mikihito Nakamori, Masaki Nakamura, Toshiyasu Ojima, Takeshi Iida, Masahiro Katsuda, Tsuji Toshiaki, Hayata Keiji, Hiroki Yamaue

Published in: Langenbeck's Archives of Surgery | Issue 6/2012

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Abstract

Purpose

This study aims to analyze the results of treatment in a series of 233 gastric cancer patients who underwent a noncurative resection.

Methods

We performed a retrospective study of patients with noncurative treatment for advanced gastric cancer who were divided into three treatment groups: total gastrectomy (TG, n = 150), distal gastrectomy (DG, n = 44), and nonresection (NR, bypass procedure or chemotherapy only, n = 39).

Results

In multivariate analysis, surgical treatment (TG) and an absence of chemotherapy were significant independent prognostic factors for a poor survival. In the late period, the overall survival rate was significantly lower in the TG group than in the DG group (p = 0.005) and was marginally lower than in the NR group (p = 0.054). The resection group had a poorer compliance for chemotherapy than the NR group, and the TG group had a poorer compliance than the DG group (p < 0.01). The morbidity rate was higher in the TG group than in the DG group (p < 0.05).

Conclusions

TG is considered to be inappropriate for the treatment of noncurative gastric cancer because of the poor prognosis, high morbidity rates, and poor compliance for chemotherapy associated with the procedure. However, noncurative DG was acceptable and postoperative chemotherapy should be used in selected patients.
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Metadata
Title
The evaluation of surgical treatment for gastric cancer patients with noncurative resection
Authors
Teiji Naka
Makoto Iwahashi
Mikihito Nakamori
Masaki Nakamura
Toshiyasu Ojima
Takeshi Iida
Masahiro Katsuda
Tsuji Toshiaki
Hayata Keiji
Hiroki Yamaue
Publication date
01-08-2012
Publisher
Springer-Verlag
Published in
Langenbeck's Archives of Surgery / Issue 6/2012
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-012-0906-z

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