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Archives of Orthopaedic and Trauma Surgery

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Open Access 01-10-2018 | Orthopaedic Surgery

The efficacy and safety of knotless barbed sutures in total joint arthroplasty: a meta-analysis of randomized-controlled trials

Authors: Yanhong Han, Weiyi Yang, Jianke Pan, Lingfeng Zeng, Guihong Liang, Jiongtong Lin, Minghui Luo, Da Guo, Jun Liu

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 10/2018

Abstract

Background

The knotless barbed sutures (KBS) are an innovative type of suture that can accelerate the placement of sutures and eliminate knot tying. Whether the KBS are safe and efficient in total joint arthroplasty (TJA) remains controversial. Therefore, we conducted a meta-analysis to evaluate its efficacy and safety.

Methods

Randomized-controlled trials (RCTs) were identified from the PubMed, Embase, and Cochrane Library databases up to October 2017. The Cochrane risk of bias tool was used to assess methodological quality. The statistical analysis was performed with RevMan 5.3.5 software.

Results

A total of five RCTs (600 participants) were included in our meta-analysis. The results showed that KBS reduced wound suture time (MD − 4.51, 95% CI − 5.37 to − 3.66, P < 0.00001) and the wound suture cost (MD − 282.63, 95% CI − 445.32 to − 119.95, P < 0.00001), and did not significantly increase the rate of complications (OR 0.77, 95% CI 0.42–1.39, P = 0.13) or intraoperative events (OR 0.86, 95% CI 0.04–17.28, P = 0.92). There were no significant differences in ROM at postoperative 6 weeks and 3 months (MD − 0.74, 95% CI − 4.19 to 2.71, P = 0.67; MD − 0.30, 95% CI − 2.62 to 2.02, P = 0.80; respectively).

Conclusion

Our findings suggest that KBS are a safe and effective method for TJA. Given the possible biases, adequately powered and better designed studies with longer follow-up are required to reach a firmer conclusion.

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Title: The efficacy and safety of knotless barbed sutures in total joint arthroplasty: a meta-analysis of randomized-controlled trials
Authors: Yanhong Han
Weiyi Yang
Jianke Pan
Lingfeng Zeng
Guihong Liang
Jiongtong Lin
Minghui Luo
Da Guo
Jun Liu
Publication date: 01-10-2018
Publisher: Springer Berlin Heidelberg
Published in: Archives of Orthopaedic and Trauma Surgery / Issue 10/2018
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-018-2979-9

At a glance: The STEP trials

Springer Medicine

The efficacy and safety of knotless barbed sutures in total joint arthroplasty: a meta-analysis of randomized-controlled trials

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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