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BMC Anesthesiology
Published in: BMC Anesthesiology 1/2017

Open Access 01-12-2017 | Research article

The effects of tramadol on postoperative shivering after sevoflurane and remifentanil anesthesia

Authors: Taku Nakagawa, Miki Hashimoto, Yasunori Hashimoto, Kazuhiro Shirozu, Sumio Hoka

Published in: BMC Anesthesiology | Issue 1/2017

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Abstract

Backgrounds

Remifentanil has been reported to cause post-anesthetic shivering (PAS). Higher doses of remifentanil reportedly induce more intense PAS. Tramadol, a synthetic opioid that acts at multiple sites, is considered to be an effective treatment for PAS, but the evidence for its therapeutic benefit after remifentanil anesthesia is limited. We investigated the effect of tramadol on the incidence of PAS after remifentanil anesthesia.

Methods

Sixty-three patients who had undergone upper abdominal surgery under general anesthesia were studied retrospectively. Tramadol was administered at induction of anesthesia. The patients were divided into four groups: HT(+), high dose remifentanil (1–1.5 μg/kg/min) with tramadol; HT(−), high dose remifentanil without tramadol; LT(+), low dose remifentanil (0.15–0.25 μg/kg/min) with tramadol; and LT(−), low dose remifentanil without tramadol. We recorded perioperative changes in nasopharyngeal temperature and episodes of PAS on emergence from anesthesia.

Results

The incidences of PAS in both tramadol treatment groups were significantly lower than the groups that did not receive tramadol. Nasopharyngeal temperature after surgery fell significantly more from baseline in the tramadol treatment groups compared with the non-treatment groups.

Conclusion

Tramadol administered at induction of anesthesia appears to suppress PAS following remifentanil anesthesia.
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Metadata
Title
The effects of tramadol on postoperative shivering after sevoflurane and remifentanil anesthesia
Authors
Taku Nakagawa
Miki Hashimoto
Yasunori Hashimoto
Kazuhiro Shirozu
Sumio Hoka
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2017
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-016-0295-x

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