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01-10-2007 | Original Article

The Effects of Increased Ischemic Times on Adipose Tissue: A Histopathologic Study Using the Epigastric Flap Model in Rats

Authors: Yusuf K. Coban, Harun Ciralik

Published in: Aesthetic Plastic Surgery | Issue 5/2007

Abstract

Little study has investigated the ischemic injury of mature adipocytes. This study researched the effects of different ischemic times on fat histology the 7th postischemic day in a rat epigastric flap model. For this study, 24 rats were randomly divided into four groups subjected, respectively, to 1, 2, 3, and 4 h of ischemia. The most severe inflammation and fat necrosis scores were seen in groups 3 and 4 (p < 0.05). According to the findings of this study, it is possible to say that fat tissue undergoes a gross necrosis after 3 or more hours of ischemia. After that ischemic time, the necrotic volume of fat tissue subjected to ischemic insult does not increase with increased ischemic time.

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Title: The Effects of Increased Ischemic Times on Adipose Tissue: A Histopathologic Study Using the Epigastric Flap Model in Rats
Authors: Yusuf K. Coban
Harun Ciralik
Publication date: 01-10-2007
Publisher: Springer New York
Published in: Aesthetic Plastic Surgery / Issue 5/2007
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI: https://doi.org/10.1007/s00266-006-0196-3

At a glance: The STEP trials

Springer Medicine

The Effects of Increased Ischemic Times on Adipose Tissue: A Histopathologic Study Using the Epigastric Flap Model in Rats

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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