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Journal of Public Health

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01-04-2016 | Original Article

The effectiveness of an NaF rinse containing fTCP on eroded enamel remineralization

Authors: Andressa Feitosa B. de Oliveira, Sapna M. Mathews, Karthikeyan Ramalingam, Bennett Amaechi

Published in: Journal of Public Health | Issue 2/2016

Abstract

Objective

The authors investigated the effectiveness of a functionalized tricalcium phosphate (fTCP) combined with a low fluoride level in a mouthrinse to reharden eroded enamel lesions.

Methods

Ninety enamel slabs attached in pairs to removable appliances were randomly assigned to three treatment groups (n = 30/group): (T1) NaF rinse (225 ppm F + 40 ppm fTCP), (T2) NaF rinse (225 ppm F; ACT^®), and (T3) no mouthrinse (saliva). While wearing the in situ appliance for 14 days, subjects brushed their teeth with 1100 ppm F toothpaste (Crest©) for 2 min, rinsed with 15 ml of water for 10s, and then rinsed with 15 ml of their assigned treatment mouthrinse. Treatment efficacy was evaluated using surface microhardness (SMH) and transverse microradiography (TMR). Intra- and intergroup comparisons (α = 0.05) were performed using the t-test and ANOVA followed by the Tukey test (HSD).

Results

With SMH, intragroup comparison (t-test) indicated significant rehardening of the eroded lesion with exposure to T1 (p < 0.001) and T2 (p < 0.01) but not with T3 However, with TMR, remineralization was only significant (p = 0.01) with T1, but not with T2 and T3. In the intergroup comparison with percentage change in SMH, T1 was significantly different from T3 (p < 0.01; Tukey HSD) but not from T2, and T2 was significantly different from T3. Intergroup comparison based on percentage mineral gain showed that T2 (p = 0.02) and T3 (p = 0.01) differed significantly from fTCP, but not between each other.

Conclusion

Addition of low level fluoride to functionalized β-tricalcium phosphate promoted rehardening of eroded enamel lesions.

Amaechi BT, Higham SM (2001) In vitro remineralisation of eroded enamel lesions by saliva. J Dent 29:371–376CrossRefPubMed

Amaechi BT, Hingham SM, Edgar VW (1998) Use of transverse microradiography to quantify mineral loss by erosion in bovine enamel. Caries Res 18:17–24

Amaechi BT, Higham SM, Edgar WM (1999) The use of gamma irradiation for the sterilization of enamel for intra-oral cariogenicity tests. J Oral Rehabil 26:809–813CrossRefPubMed

Amaechi BT, Karthikeyan R, Poornima KM, Najibfard K, Mackey AC, Karlinsey RL (2010) Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study. Clin Cosmet Investig Dent 2:93–100PubMedPubMedCentral

Amaechi BT, Ramalingam K, Mensinkai PK, Chedjieu I (2012) In situ remineralization of early caries by a new high-fluoride dentifrice. Gen Dent 60(4):186–192

Attin T, Knöfel S, Buchalla W, Tütüncü R (2001) In situ evaluation of different remineralization periods to decrease brushing abrasion of demineralized enamel. Caries Res 35:216–222CrossRefPubMed

Attin T, Siegel S, Buchalla W, Lennon ÀM, Hannig C, Becker K (2004) Brushing abrasion of softened and remineralised dentin: an in situ study. Caries Res 38:62–66CrossRefPubMed

Cochrane NJ, Cai F, Huq NL, Burrow MF, Reynolds EC (2010) New approaches to enhance remineralisation of tooth enamel. J Dent Res 89:1187–1197CrossRefPubMed

Fejerskov O, Larsen MJ, Richards A, Baelum V (1994) Dental tissue effects of fluoride. Adv Dent Res 8:15–31PubMed

Ganss C, Klimek J, Schäffer U, Spall T (2001) Effectiveness of two fluoridation measures on erosion progression in human enamel and dentine in vitro. Caries Res 35:325–330CrossRefPubMed

Ghosh SK, Nandi SK, Kundu B, Datta S, De DK, Roy SK, Basu D (2008) In vivo response of porous hydroxyapatite and beta-tricalcium phosphate prepared by aqueous solution combustion method and comparison with bioglass scaffolds. J Biomed Mater Res 86:217–227CrossRef

Imfeld T (1996) Dental erosion: definition, classification and links. Eur J Oral Sci 104:207–214CrossRef

Jaeggi T, Lussi A (1999) Toothbrush abrasion of erosively altered enamel after intraoral exposure to saliva: An in situ study. Caries Res 33:455–461CrossRefPubMed

Jaeggi T, Lussi A (2006) Prevalence, incidence and distribution of erosion. In: Lussi A (ed) Dental Erosion: from diagnosis to therapy. Monography in Oral Science. Karger, Basel, pp 44–65CrossRef

Karlinsey RL, Pfarrer AM (2012) Fluoride plus functionalized β-TCP: a promising combination for robust remineralization. Adv Dent Res 24:48–52CrossRefPubMedPubMedCentral

Karlinsey RL, Yi K, Duhn CW (2006) Nucleation and growth of apatite by a self-assembled polycrystalline bioceramic. Bioinspir Biomim 1:12–19CrossRefPubMed

Karlinsey RL, Mackey AC, Walker ER, Frederick KE (2008) Spectroscopic evaluation of native, milled, and functionalized β-TCP seeding into dental enamel lesions. J Mater Sci 44:5013–5016CrossRef

Karlinsey RL, Mackey AC, Walker ER, Frederick KE, Fowler CX (2009) In vitro evaluation of eroded enamel treated with fluoride and a prospective tricalcium phosphate agent. J Dent Oral Hyg 1:52–58

Karlinsey RL, Mackey AC, Walke ER, Frederick DE (2010a) Surfactant-modified β-TCP: structure, properties, and in vitro remineralisation of subsurface enamel lesions. J Mater Sci Mater Med 21:2009–2020CrossRefPubMed

Karlinsey RL, Mackey AC, Walker ER, Frederick KE (2010b) Preparation, characterization and in vitro efficacy of an acid-modified β-TCP material for dental hard-tissue remineralisation. Acta Biomater 6:969–978CrossRefPubMed

Lippert F, Parker DM, Jandt KD (2004) In vitro demineralization/remineralisation cycles at human tooth enamel surfaces investigated by AFM and nanoindentation. J Colloid Interface Sci 280:442–448CrossRefPubMed

Lussi A (2006) Erosive tooth wear—a multifactorial condition of growing concern and increasing knowledge. In: Lussi A (ed) Dental erosion. Karger, Basel, pp 1–8CrossRef

Magalhaes AC, Wiegand A, Rios D, Buzalaf MA, Lussi A (2011) Fluoride in dental erosion. Monogr Oral Sci 22:158–170CrossRefPubMed

Magio B, Guibert RG, Mason SC, Karwal R, Rees GD, Kelly S, Zero DT (2010) Evaluation of mouthrinse and dentifrice regimens in an in situ erosion remineralisation model. J Dent 38:37–44CrossRef

Mathews MS, Amaechi BT, Ramalingam K, Ccahuana-Vasquez RA, Chedjieu IP, Mackey AC, Karlinsey RL (2012) In situ remineralisation of eroded enamel lesions by NaF rinses. Arch Oral Biol 57(5):525–530CrossRefPubMed

Poggio C, Lombardini M, Colombo M, Bianchi S (2010) Impact of two toothpastes on repairing enamel eroson produced by a soft drink: an AFM in vitro study. J Dent 38:868–874CrossRefPubMed

Reynolds EC, Cai F, Shen P, Walker GD (2003) Retention in plaque and remineralisation of enamel lesions by various forms of calcium in a mouthrinse or sugar-free chewing gum. J Dent Res 82:206–211CrossRefPubMed

Srinivasan N, Kavitha M, Longanathan SC (2010) Comparison on the remineralisation potential of CPP-ACP and CPP-ACP with 900ppm fluoride on eroded human enamel: an in situ study. Arch Oral Biol 55:541–544CrossRefPubMed

Vogel GL, Shim D, Schumacher GE, Carey CM, Chow LC, Takagi S (2006) Salivary fluoride from fluoride dentifrices of rinses after use of a calcium pre-rinse or calcium dentifrice. Caries Res 40:449–454CrossRefPubMed

Voronets J, Jaeggi T, Buergin W, Lussi A (2008) Controlled toothbrush abrasion of softened human enamel. Caries Res 42:286–290CrossRefPubMed

Title: The effectiveness of an NaF rinse containing fTCP on eroded enamel remineralization
Authors: Andressa Feitosa B. de Oliveira
Sapna M. Mathews
Karthikeyan Ramalingam
Bennett Amaechi
Publication date: 01-04-2016
Publisher: Springer Berlin Heidelberg
Published in: Journal of Public Health / Issue 2/2016
Print ISSN: 2198-1833
Electronic ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-016-0709-8

At a glance: The STEP trials

Springer Medicine

The effectiveness of an NaF rinse containing fTCP on eroded enamel remineralization

Abstract

Objective

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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