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Immunity & Ageing
Published in: Immunity & Ageing 1/2024

Open Access 01-12-2024 | Comment

The effect of T cell aging on the change of human tissue structure

Authors: Ling-ling Xu, Xiang Chen, Jing-ping Cheng

Published in: Immunity & Ageing | Issue 1/2024

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Abstract

The trend of aging of the global population is becoming more and more significant, and the incidence of age-related diseases continues to rise.This phenomenon makes the problem of aging gradually attracted wide attention of the society, and gradually developed into an independent research field.As a vital defense mechanism of the human body, the immune system changes significantly during the aging process.Age-induced changes in the body’s immune system are considered harmful and are commonly referred to as immune aging, which may represent the beginning of systemic aging.Immune cells, especially T cells, are the biggest influencers and participants in age-related deterioration of immune function, making older people more susceptible to different age-related diseases.More and more evidence shows that T cells play an important role in the change of human tissue structure after aging, which fundamentally affects the health and survival of the elderly.In this review, we discuss the general characteristics of age-related T cell immune alterations and the possible effects of aging T cells in various tissue structures in the human body.
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Metadata
Title
The effect of T cell aging on the change of human tissue structure
Authors
Ling-ling Xu
Xiang Chen
Jing-ping Cheng
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Immunity & Ageing / Issue 1/2024
Electronic ISSN: 1742-4933
DOI
https://doi.org/10.1186/s12979-024-00433-4

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