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Radiation Oncology
Published in: Radiation Oncology 1/2014

Open Access 01-12-2014 | Research

The effect of radiation therapy on the mechanical and morphological properties of the enamel and dentin of deciduous teeth—an in vitro study

Authors: Talitha de Siqueira Mellara, Regina Guenka Palma-Dibb, Harley Francisco de Oliveira, Francisco Wanderley Garcia Paula-Silva, Paulo Nelson-Filho, Raquel Assed Bezerra da Silva, Léa Assed Bezerra da Silva, Alexandra Mussolino de Queiroz

Published in: Radiation Oncology | Issue 1/2014

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Abstract

Purpose

To evaluate the effects of radiation therapy on deciduous teeth.

Materials and methods

The enamel and dentin microhardness (n = 12) was evaluated at 3 depths, both before (control) and after each 10 Gy of irradiation and up to a dose of 60 Gy. The morphology was evaluated via scanning electron microscopy (SEM) (n = 8). The data were analyzed using a two-way analysis of variance (ANOVA) and Tukey’s test (α = 5%).

Results

The enamel microhardness, as a whole, increased (p < 0.05) after a dose of 60 Gy (211.4 KH), mostly in the superficial enamel. There was a significant difference between the values of nonirradiated dentin microhardness (28.9 KH) compared with dentin that was irradiated with doses of 10 Gy (23.8 KH), 20 Gy (25.6 KH), 30 Gy (24.8 KH), and 40 Gy (25.7 KH) (p < 0.05). There was no difference between nonirradiated dentin and dentin irradiated with 60 Gy (p > 0.05). The highest mean value of microhardness (29.9 KH) (p < 0.05) was found in the middle dentin. The groups that were irradiated with doses of 30 and 60 Gy exhibited greater surface changes in their enamel and dentin compared with the nonirradiated groups for all regions, exhibiting an amorphous surface upon increase of the irradiation doses.

Conclusions

The enamel microhardness increased at a dose of 60 Gy, whereas the value of the dentin microhardness did not change. A progressive disruption of enamel and dentin morphology was found with the increased radiation dose.
Appendix
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Metadata
Title
The effect of radiation therapy on the mechanical and morphological properties of the enamel and dentin of deciduous teeth—an in vitro study
Authors
Talitha de Siqueira Mellara
Regina Guenka Palma-Dibb
Harley Francisco de Oliveira
Francisco Wanderley Garcia Paula-Silva
Paulo Nelson-Filho
Raquel Assed Bezerra da Silva
Léa Assed Bezerra da Silva
Alexandra Mussolino de Queiroz
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2014
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/1748-717X-9-30

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