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01-12-2008 | Original Article

The effect of periodontal treatment on metabolic control of type 1 diabetes mellitus

Authors: Fernando Llambés, Francisco-Javier Silvestre, Antonio Hernández-Mijares, Rami Guiha, Raúl Caffesse

Published in: Clinical Oral Investigations | Issue 4/2008

Abstract

The objective of this investigation was to study the effect of nonsurgical periodontal treatment, with or without systemic administration of doxycycline, on the metabolic control of patients with type 1 diabetes. Sixty type 1 diabetic subjects with moderate to severe periodontitis were recruited. Periodontal parameters were measured, and blood samples were obtained to evaluate glycosylated hemoglobin (HbA1c). Group 1 (30 patients) was treated with scaling, root planning, and chlorhexidine rinses for 3 months in conjunction with systemic administration of doxycycline (100 mg once a day for 15 days). Group 2 (30 patients) received the same periodontal treatment but without the use of doxycycline. The paired Student t-test was used to detect differences between glycosylated hemoglobin means before and 3 months after periodontal treatment in group 1 and group 2 separately. Changes in mean HbA1c after treatment were 0.07% in group 1 and –0.06% in group 2, which were not statistically significant after 3 months. Significant changes were not found even in patients with the best response to periodontal treatment. Periodontal treatment in type 1 diabetic patients after 3 months follow-up did not improve metabolic control of diabetes as measured by glycosylated hemoglobin.

Adams TM, HA-8160, Menarini Diagnostics

Itachi 747, Roche

Cavitron, Dentsply Company, Madrid, Spain

Gracey, HuFriedy Instruments, Chicago, IL, USA

PerioAid 0.2%, Dentaid Company, Barcelona, Spain

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Title: The effect of periodontal treatment on metabolic control of type 1 diabetes mellitus
Authors: Fernando Llambés
Francisco-Javier Silvestre
Antonio Hernández-Mijares
Rami Guiha
Raúl Caffesse
Publication date: 01-12-2008
Publisher: Springer-Verlag
Published in: Clinical Oral Investigations / Issue 4/2008
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-008-0201-0

At a glance: The STEP trials

Springer Medicine

The effect of periodontal treatment on metabolic control of type 1 diabetes mellitus

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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