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International Urogynecology Journal
Published in: International Urogynecology Journal 8/2013

01-08-2013 | Original Article

The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery

Authors: Jeannine M. Miranne, Vrishali Lopes, Cassandra L. Carberry, Vivian W. Sung

Published in: International Urogynecology Journal | Issue 8/2013

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Abstract

Introduction and hypothesis

This study evaluates the effect of baseline pelvic organ prolapse (POP) severity on improvement in overactive bladder (OAB) symptoms after pelvic reconstructive surgery.

Methods

We performed a retrospective cohort study of women with POP and OAB who underwent surgical correction of symptomatic apical and/or anterior POP. OAB was defined as an affirmative response to item #15 (urinary frequency) and/or item #16 (urge incontinence) of the Pelvic Floor Distress Inventory (PFDI). POP severity was dichotomized as Pelvic Organ Prolapse Quantification (POP-Q) stage 1–2 versus stage 3–4. Our primary outcome was complete resolution or improvement of urinary frequency or urge incontinence on the PFDI 12 months postoperatively.

Results

At 12 months postoperative, 41 (89%) women with stage 1–2 POP versus 47 (85 %) with stage 3–4 POP reported improvement in urinary frequency (p = 0.58). Thirty five (90 %) with stage 1–2 and 34 (85 %) with stage 3–4 POP reported improvement in urge incontinence (p = 0.74). On multiple logistic regression, women with stage 3–4 POP had a decreased odds of improvement in frequency or urge incontinence compared with women with stage 1–2 POP (adjusted odds ration [AOR] = 0.06 [95 % CI 0.01–0.67]), after adjusting for confounders.

Conclusions

Women with coexisting POP and OAB who undergo surgical correction of POP experience improvement in OAB symptoms after surgery, although women with more severe POP may be at a higher risk of persistent frequency or urge incontinence.
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Metadata
Title
The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery
Authors
Jeannine M. Miranne
Vrishali Lopes
Cassandra L. Carberry
Vivian W. Sung
Publication date
01-08-2013
Publisher
Springer London
Published in
International Urogynecology Journal / Issue 8/2013
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-012-2000-z

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