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Open Access 01-08-2009 | Original Article

The effect of exercise counselling with feedback from a pedometer on fatigue in adult survivors of childhood cancer: a pilot study

Authors: Ria Blaauwbroek, Martijn J. Bouma, Wemke Tuinier, Klaas H. Groenier, Matthieu H. G. de Greef, Betty Meyboom- de Jong, Willem A. Kamps, Aleida Postma

Published in: Supportive Care in Cancer | Issue 8/2009

Abstract

Objective

The aim of this study was to evaluate the results of home-based exercise counselling with feedback from a pedometer on fatigue in adult survivors of childhood cancer.

Patients

Adult survivors of childhood cancer were recruited from the long-term follow-up clinic of the University Medical Centre Groningen, The Netherlands. A score of 70 mm on a visual analogue scale (scale, 0–100 mm) for fatigue was used as an inclusion criterion. Controls were recruited by the survivors among their healthy siblings or peers.

Methods

During 10 weeks, the counselor encouraged the survivors to change their lifestyle and enhance daily physical activity such as walking, cycling, housekeeping and gardening. As a feedback to their physical activity, the daily number of steps of each survivor was measured by a pedometer and registered using an online step diary at the start of the programme and after 4 and 10 weeks. Fatigue was the primary outcome measure, assessed with the Checklist Individual Strength (CIS) at start (T0), 10 weeks (T10) and 36 weeks (T36). Thirty-three healthy age-matched control persons were asked to complete the CIS.

Results

Out of 486 cancer survivors, 453 were interested and were asked to complete the VAS to measure fatigue; 67 out of 254 respondents met the inclusion criteria, 21 refused, 46 were enrolled and eight dropped out during the study. The mean scores on the CIS in the survivors at T0 was 81.42 (SD ± 20.14) and at T10 62.62 (SD ± 20.68), which was a significant improvement (p < 0.0005). At T36, the end of the study, the mean CIS score was 63.67 (SD ± 23.12); this was a significant improvement compared with the mean CIS at the start (p < 0.0005). There was no significant difference in the mean CIS scores of the controls during the follow-up period.

Conclusion

The stimulation of daily physical activity using exercise counselling and a pedometer over 10 weeks leads to a significant decrease in fatigue in adult survivors of childhood cancer, and this improvement lasts for at least 36 weeks.

Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ et al (2000) Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 32:S498–S504 doi:10.1097/00005768-200009001-00009 PubMedCrossRef

Ainsworth BE, Youmans CP (1993) Tools for physical activity counseling in medical practice. Obes Res 10(Suppl 1):69S–75S doi:10.1038/oby.2002.193

Bates DW, Schmitt W, Buchwald D, Ware NC, Lee J, Thoyer E et al (2006) Prevalence of fatigue and chronic fatigue syndrome in a primary care practice. Arch Intern Med 153:2759–2765 doi:10.1001/archinte.153.24.2759 CrossRef

de Blok BM, de Greef MH, ten Hacken NH, Sprenger SR, Postema K, Wempe JB (2006) The effects of a lifestyle physical activity counseling program with feedback of a pedometer during pulmonary rehabilitation in patients with COPD: a pilot study. Patient Educ Couns 61:48–55 doi:10.1016/j.pec.2005.02.005 PubMedCrossRef

Carlson LE, Smith D, Russell J, Fibich C, Whittaker T (2006) Individualized exercise program for the treatment of severe fatigue in patients after allogeneic hematopoietic stem-cell transplant: a pilot study. Bone Marrow Transplant 37:945–954 doi:10.1038/sj.bmt.1705343 PubMedCrossRef

Chen MK (1986) The epidemiology of self-perceived fatigue among adults. Prev Med 15:74–81 doi:10.1016/0091-7435(86)90037-X PubMedCrossRef

Courneya KS, Mackey JR, Bell GJ, Jones LW, Field CJ, Fairey AS (2003) Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol 21:1660–1668 doi:10.1200/JCO.2003.04.093 PubMedCrossRef

Dimeo FC (2001) Effects of exercise on cancer-related fatigue. Cancer 92:1689–1693 doi:10.1002/1097-0142(20010915)92:6+<1689::AID-CNCR1498>3.0.CO;2-H PubMedCrossRef

Dimeo FC, Tilmann MH, Bertz H, Kanz L, Mertelsmann R, Keul J (1997) Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation. Cancer 79:1717–1722 doi:10.1002/(SICI)1097-0142(19970501)79:9<1717::AID-CNCR12>3.0.CO;2-0 PubMedCrossRef

10.

Dunn AL, Andersen RE, Jakicic JM (1998) Lifestyle physical activity interventions. History, short- and long-term effects, and recommendations. Am J Prev Med 15:398–412 doi:10.1016/S0749-3797(98)00084-1 PubMedCrossRef

11.

Fobair P, Hoppe RT, Bloom J, Cox R, Varghese A, Spiegel D (1986) Psychosocial problems among survivors of Hodgkin's disease. J Clin Oncol 4:805–814PubMed

12.

Gielissen MF, Verhagen S, Witjes F, Bleijenberg G (2006) Effects of cognitive behavior therapy in severely fatigued disease-free cancer patients compared with patients waiting for cognitive behavior therapy: a randomized controlled trial. J Clin Oncol 24:4882–4887 doi:10.1200/JCO.2006.06.8270 PubMedCrossRef

13.

Gijsen BCM, Koppejan-Rensenbrink AG (2005) Herstel&Balans. Groepsrevalidatie in de oncologie. Tijdschrift voor kanker 2005

14.

Glaus A, Crow R, Hammond S (1996) A qualitative study to explore the concept of fatigue/tiredness in cancer patients and in healthy individuals. Eur J Cancer Care (Engl) 2(Suppl):8–23 doi:10.1111/j.1365-2354.1996.tb00247.x CrossRef

15.

Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA et al (2007) Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 39:1423–1434 doi:10.1249/mss.0b013e3180616b27 PubMedCrossRef

16.

Jones LW, Courneya KS (2002) Exercise counseling and programming preferences of cancer survivors. Cancer Pract 10:208–215 doi:10.1046/j.1523-5394.2002.104003.x PubMedCrossRef

17.

Kahn EB, Ramsey LT, Brownson RC, Heath GW, Howze EH, Powell KE, et al (2002) The effectiveness of interventions to increase physical activity. A systematic review. Am J Prev Med 22(4)(Suppl):73–107. doi:10.1016/S0749-3797(02)00434-8 PubMedCrossRef

18.

Karvinen KH, Courneya KS, Campbell KL, Pearcey RG, Dundas G, Capstick V et al (2006) Exercise preferences of endometrial cancer survivors: a population-based study. Cancer Nurs 29:259–265 doi:10.1097/00002820-200607000-00001 PubMedCrossRef

19.

Langeveld NE, Grootenhuis MA, Voute PA, de Haan RJ, Van den BC (2003) No excess fatigue in young adult survivors of childhood cancer. Eur J Cancer 39:204–214 doi:10.1016/S0959-8049(02)00629-9 PubMedCrossRef

20.

Langeveld N, Ubbink M, Smets E (2000) ‘I don’t have any energy’: The experience of fatigue in young adult survivors of childhood cancer. Eur J Oncol Nurs 4:20–28 doi:10.1054/ejon.1999.0063 PubMedCrossRef

21.

Lewis G, Wessely S (1992) The epidemiology of fatigue: more questions than answers. J Epidemiol Community Health 46:92–97PubMedCrossRef

22.

Locke EA, Latham GP (2002) Building a practically useful theory of goal setting and task motivation. A 35-year odyssey. Am Psychol 57:705–717 doi:10.1037/0003-066X.57.9.705 PubMedCrossRef

23.

Makowiec-Dabrowska T, Koszada-Wlodarczyk W (2006) The CIS20R Questionnaire and its suitability for prolonged fatigue studies. Med Press 57:335–345

24.

Meeske KA, Patel SK, Palmer SN, Nelson MB, Parow AM (2007) Factors associated with health-related quality of life in pediatric cancer survivors. Pediatr Blood Cancer 49:298–305 doi:10.1002/pbc.20923 PubMedCrossRef

25.

Meeske KA, Siegel SE, Globe DR, Mack WJ, Bernstein L (2005) Prevalence and correlates of fatigue in long-term survivors of childhood leukemia. J Clin Oncol 23:5501–5510 doi:10.1200/JCO.2005.03.210 PubMedCrossRef

26.

Mendoza TR, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK et al (1999) The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer 85:1186–1196 doi:10.1002/(SICI)1097-0142(19990301)85:5<1186::AID-CNCR24>3.0.CO;2-N PubMedCrossRef

27.

Mock V, Atkinson A, Barsevick A, Cella D, Cimprich B, Cleeland C et al (2000) NCCN practice guidelines for cancer-related fatigue. Oncology 14:151–161PubMed

28.

Mulrooney DA, Ness KK, Neglia JP, Whitton JA, Green DM, Zeltzer LK et al (2008) Fatigue and sleep disturbance in adult survivors of childhood cancer: a report from the childhood cancer survivor study (CCSS). Sleep 31:271–281PubMed

29.

Ness KK, Gurney JG, Zeltzer LK, Leisenring W, Mulrooney DA, Nathan PC et al (2008) The impact of limitations in physical, executive, and emotional function on health-related quality of life among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Arch Phys Med Rehabil 2008:128–136 doi:10.1016/j.apmr.2007.08.123 CrossRef

30.

Oldervoll LM, Kaasa S, Knobel H, Loge JH (2003) Exercise reduces fatigue in chronic fatigued Hodgkins disease survivors–results from a pilot study. Eur J Cancer 39:57–63 doi:10.1016/S0959-8049(02)00483-5 PubMedCrossRef

31.

Pinto BM, Maruyama NC (1999) Exercise in the rehabilitation of breast cancer survivors. Psychooncology 8:191–206 doi:10.1002/(SICI)1099-1611(199905/06)8:3<191::AID-PON355>3.0.CO;2-T PubMedCrossRef

32.

Prochaska JO, DiClemente CC (1992) Stages of change in the modification of problem behaviors. Prog Behav Modif 28:183–218PubMed

33.

Rubak S, Sandbaek A, Lauritzen T, Christensen B (2005) Motivational interviewing: a systematic review and meta-analysis. Br J Gen Pract 55:305–312PubMed

34.

Schneider PL, Crouter SE, Bassett DR (2004) Pedometer measures of free-living physical activity: comparison of 13 models. Med Sci Sports Exerc 36:331–335 doi:10.1249/01.MSS.0000113486.60548.E9 PubMedCrossRef

35.

Segar ML, Katch VL, Roth RS, Garcia AW, Portner TI, Glickman SG et al (1998) The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum J 25:107–113

36.

Servaes P, van der WS, Prins J, Verhagen S, Bleijenberg G (2001) Fatigue in disease-free cancer patients compared with fatigue in patients with chronic fatigue syndrome. Support Care Cancer 9:11–17 doi:10.1007/s005200000165 PubMedCrossRef

37.

Tudor-Locke C, Bassett DR Jr (2004) How many steps/day are enough? Preliminary pedometer indices for public health. Sports Med 32:1–8 doi:10.2165/00007256-200434010-00001 CrossRef

38.

Tudor-Locke C, Bell RC, Myers AM, Harris SB, Ecclestone NA, Lauzon N et al (2004) Controlled outcome evaluation of the First Step Program: a daily physical activity intervention for individuals with type II diabetes. Int J Obes Relat Metab Disord 28:113–119 doi:10.1038/sj.ijo.0802485 PubMedCrossRef

39.

Tudor-Locke C, Burkett L, Reis JP, Ainsworth BE, Macera CA, Wilson DK (2005) How many days of pedometer monitoring predict weekly physical activity in adults? Prev Med 40:293–298 doi:10.1016/j.ypmed.2004.06.003 PubMedCrossRef

40.

Tudor-Locke C, Sisson SB, Lee SM, Craig CL, Plotnikoff RC, Bauman A (2006) Evaluation of quality of commercial pedometers. Can J Public Health 97(Suppl 1):S10–S16PubMed

41.

Vallance JK, Courneya KS, Jones LW, Reiman T (2005) Differences in quality of life between non-Hodgkin’s lymphoma survivors meeting and not meeting public health exercise guidelines. Psychooncology 14:979–991 doi:10.1002/pon.910 PubMedCrossRef

42.

Vallance JK, Courneya KS, Jones LW, Reiman T (2006) Exercise preferences among a population-based sample of non-Hodgkin's lymphoma survivors. Eur J Cancer Care (Engl) 15:34–43 doi:10.1111/j.1365-2354.2005.00617.x CrossRef

43.

Vallance JK, Courneya KS, Plotnikoff RC, Yasui Y, Mackey JR (2007) Randomized controlled trial of the effects of print materials and step pedometers on physical activity and quality of life in breast cancer survivors. J Clin Oncol 25:2352–2359 doi:10.1200/JCO.2006.07.9988 PubMedCrossRef

44.

Vercoulen JH (1999) De Checklist Individual Strength (CIS). Gedragstherapie 32:131–136

45.

Vercoulen JH, Swanink CM, Fennis JF, Galama JM, Van Der Meer JW, Bleijenberg G (1994) Dimensional assessment of chronic fatigue syndrome. J Psychosom Res 38:383–392 doi:10.1016/0022-3999(94)90099-X PubMedCrossRef

46.

Wasserman AL, Thompson EI, Wilimas JA, Fairclough DL (1987) The psychological status of survivors of childhood/adolescent Hodgkin’s disease. Am J Dis Child 141:626–631PubMed

47.

Zeltzer LK, Chen E, Weiss R, Guo MD, Robison LL, Meadows AT et al (1997) Comparison of psychologic outcome in adult survivors of childhood acute lymphoblastic leukemia versus sibling controls: a cooperative Children’s Cancer Group and National Institutes of Health study. J Clin Oncol 15:547–556PubMed

Title: The effect of exercise counselling with feedback from a pedometer on fatigue in adult survivors of childhood cancer: a pilot study
Authors: Ria Blaauwbroek
Martijn J. Bouma
Wemke Tuinier
Klaas H. Groenier
Matthieu H. G. de Greef
Betty Meyboom- de Jong
Willem A. Kamps
Aleida Postma
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Supportive Care in Cancer / Issue 8/2009
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-008-0533-y

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