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European Archives of Psychiatry and Clinical Neuroscience
Published in: European Archives of Psychiatry and Clinical Neuroscience 6/2013

01-09-2013 | Original Paper

The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study

Authors: Peter Falkai, Berend Malchow, Thomas Wobrock, Oliver Gruber, Andrea Schmitt, William G. Honer, Frank-Gerald Pajonk, Frank Sun, Tyrone D. Cannon

Published in: European Archives of Psychiatry and Clinical Neuroscience | Issue 6/2013

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Abstract

Via influencing brain plasticity, aerobic exercise could contribute to the treatment of schizophrenia patients. As previously shown, physical exercise increases hippocampus volume and improves short-term memory. We now investigated gray matter density and brain surface expansion in this sample using MRI-based cortical pattern matching methods. Comparing schizophrenia patients to healthy controls before and after 3 months of aerobic exercise training (cycling) plus patients playing table football yielded gray matter density increases in the right frontal and occipital cortex merely in healthy controls. However, respective exercise effects might be attenuated in chronic schizophrenia, which should be verified in a larger sample.
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Metadata
Title
The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study
Authors
Peter Falkai
Berend Malchow
Thomas Wobrock
Oliver Gruber
Andrea Schmitt
William G. Honer
Frank-Gerald Pajonk
Frank Sun
Tyrone D. Cannon
Publication date
01-09-2013
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Psychiatry and Clinical Neuroscience / Issue 6/2013
Print ISSN: 0940-1334
Electronic ISSN: 1433-8491
DOI
https://doi.org/10.1007/s00406-012-0383-y

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