Skip to main content
Top
Published in: Nutrition Journal 1/2011

Open Access 01-12-2011 | Short report

The duration of diarrhea and fever is associated with growth faltering in rural Malawian children aged 6-18 months

Authors: Ariana Weisz, Gus Meuli, Chrissie Thakwalakwa, Indi Trehan, Kenneth Maleta, Mark Manary

Published in: Nutrition Journal | Issue 1/2011

Login to get access

Abstract

Nutrition support programs that only focus upon better complementary feeding remain an insufficient means of limiting growth faltering in vulnerable populations of children. To determine if symptoms of acute infections correlate with the incidence of growth faltering in rural Malawian children, the associations between fever, diarrhea, and cough with anthropometric measures of stunting, wasting, and underweight were investigated. Data were analyzed from a trial where 209 children were provided with adequate complementary food and followed fortnightly from 6-18 months of age. Linear mixed model analysis was used to test for associations. Diarrheal disease was inversely associated with changes in height-for-age Z-score (HAZ), mid-upper arm circumference Z-score (MUACZ), and weight-for-age Z-score (WAZ). Fever was also inversely associated with changes in MUACZ and WAZ. These results suggest that initiatives to reduce febrile and diarrheal diseases are needed in conjunction with improved complementary feeding to limit growth faltering in rural Malawi.
Literature
1.
go back to reference Bryce J, Boschi-Pinto C, Shibuya K, Black RE, CHERG: WHO estimates of the cause of death in children. Lancet. 2005, 365: 1147-52. 10.1016/S0140-6736(05)71877-8.CrossRefPubMed Bryce J, Boschi-Pinto C, Shibuya K, Black RE, CHERG: WHO estimates of the cause of death in children. Lancet. 2005, 365: 1147-52. 10.1016/S0140-6736(05)71877-8.CrossRefPubMed
2.
go back to reference Black RE: Would control of childhood infectious diseases reduce malnutrition?. Acta Peadiatr Scand Suppl. 1991, 374: 133-140. 10.1111/j.1651-2227.1991.tb12016.x.CrossRef Black RE: Would control of childhood infectious diseases reduce malnutrition?. Acta Peadiatr Scand Suppl. 1991, 374: 133-140. 10.1111/j.1651-2227.1991.tb12016.x.CrossRef
3.
go back to reference Scrimshaw NS, SanGiovanni JP: Synergism of nutrition, infection, and immunity: an overview. Am J Clin Nutr. 1997, 66: 464S-477S.PubMed Scrimshaw NS, SanGiovanni JP: Synergism of nutrition, infection, and immunity: an overview. Am J Clin Nutr. 1997, 66: 464S-477S.PubMed
4.
go back to reference WHO Expert Committee on Physical Status: Physical status: the use and interpretation of anthropometry, WHO technical report series 854. 1995, Geneva WHO Expert Committee on Physical Status: Physical status: the use and interpretation of anthropometry, WHO technical report series 854. 1995, Geneva
5.
go back to reference UNICEF: Maternal and Newborn Health. State of the World's Children. 2009, New York: UNICEF UNICEF: Maternal and Newborn Health. State of the World's Children. 2009, New York: UNICEF
6.
go back to reference WHO: World Health Statistics 2010. 2010, Geneva WHO: World Health Statistics 2010. 2010, Geneva
7.
go back to reference USAID: MCH Program Description, Malawi. 2008, Washington, D.C USAID: MCH Program Description, Malawi. 2008, Washington, D.C
8.
go back to reference Shrimpton R, Victora CG, de Onis M, Lima RA, Blössner M, Clugston G: Worldwide timing of growth faltering: implications for nutritional interventions. Pediatrics. 2001, 107: e75-10.1542/peds.107.5.e75.CrossRefPubMed Shrimpton R, Victora CG, de Onis M, Lima RA, Blössner M, Clugston G: Worldwide timing of growth faltering: implications for nutritional interventions. Pediatrics. 2001, 107: e75-10.1542/peds.107.5.e75.CrossRefPubMed
9.
go back to reference Maleta K, Virtanen S, Espo M, Kulmala T, Ashorn P: Timing of growth faltering in rural Malawi. Arch Dis Child. 2003, 88: 574-578. 10.1136/adc.88.7.574.CrossRefPubMedPubMedCentral Maleta K, Virtanen S, Espo M, Kulmala T, Ashorn P: Timing of growth faltering in rural Malawi. Arch Dis Child. 2003, 88: 574-578. 10.1136/adc.88.7.574.CrossRefPubMedPubMedCentral
10.
go back to reference Lin CA, Manary MJ, Maleta K, Briend A, Ashorn P: An energy dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months. J Nutr. 2008, 138: 593-598.PubMed Lin CA, Manary MJ, Maleta K, Briend A, Ashorn P: An energy dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6-18 months. J Nutr. 2008, 138: 593-598.PubMed
11.
go back to reference Pan American Health Organization: Guiding principles for complementary feeding of the breastfed child. 2003, Washington Pan American Health Organization: Guiding principles for complementary feeding of the breastfed child. 2003, Washington
12.
go back to reference Morris SS, Carletto C, Hoddinott J, Christiaensen LJM: Validity of rapid estimates of household wealth and income for health surveys in rural Africa. J Epidemiol Community Health. 2000, 54: 381-387. 10.1136/jech.54.5.381.CrossRefPubMedPubMedCentral Morris SS, Carletto C, Hoddinott J, Christiaensen LJM: Validity of rapid estimates of household wealth and income for health surveys in rural Africa. J Epidemiol Community Health. 2000, 54: 381-387. 10.1136/jech.54.5.381.CrossRefPubMedPubMedCentral
13.
go back to reference Van de Poel E, Hosseinpoor AR, Speybroeck N, Van Ourti T, Vega J: Socioeconomic inequality in malnutrition in developing countries. Bull World Health Organ. 2008, 86: 282-291. 10.2471/BLT.07.044800.CrossRefPubMedPubMedCentral Van de Poel E, Hosseinpoor AR, Speybroeck N, Van Ourti T, Vega J: Socioeconomic inequality in malnutrition in developing countries. Bull World Health Organ. 2008, 86: 282-291. 10.2471/BLT.07.044800.CrossRefPubMedPubMedCentral
14.
go back to reference Jahn A, Floydd S, McGrath N, et al: Child mortality in rural Malawi: HIV closes the survival gap between the socio-economic strata. PLoS ONE. 2010, 5: e11320-10.1371/journal.pone.0011320.CrossRefPubMedPubMedCentral Jahn A, Floydd S, McGrath N, et al: Child mortality in rural Malawi: HIV closes the survival gap between the socio-economic strata. PLoS ONE. 2010, 5: e11320-10.1371/journal.pone.0011320.CrossRefPubMedPubMedCentral
15.
go back to reference WHO Multicentre Growth Reference Study Group: WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. 2006, Geneva WHO Multicentre Growth Reference Study Group: WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. 2006, Geneva
16.
go back to reference Lartey A, Manu A, Brown KH, Peerson JM, Dewey KG: Predictors of growth from 1 to 18 months among breast-fed Ghanaian infants. Eur J Clin Nutr. 2000, 54: 41-49. 10.1038/sj.ejcn.1600891.CrossRefPubMed Lartey A, Manu A, Brown KH, Peerson JM, Dewey KG: Predictors of growth from 1 to 18 months among breast-fed Ghanaian infants. Eur J Clin Nutr. 2000, 54: 41-49. 10.1038/sj.ejcn.1600891.CrossRefPubMed
17.
go back to reference Rowland MGM, Cole TJ, Whitehead RG: A quantitative study into the role of infection in determining nutritional status in Gambian village children. Br J Nutr. 1977, 37: 441-450. 10.1079/BJN19770047.CrossRefPubMed Rowland MGM, Cole TJ, Whitehead RG: A quantitative study into the role of infection in determining nutritional status in Gambian village children. Br J Nutr. 1977, 37: 441-450. 10.1079/BJN19770047.CrossRefPubMed
18.
go back to reference Kossman J, Nestel P, Herrera MG, El-Amin A, Fawzi WW: Undernutrition and childhood infections: a prospective study of childhood infections in relation to growth in Sudan. Acta Paediatr. 2000, 89: 1122-1128. 10.1080/713794561.CrossRef Kossman J, Nestel P, Herrera MG, El-Amin A, Fawzi WW: Undernutrition and childhood infections: a prospective study of childhood infections in relation to growth in Sudan. Acta Paediatr. 2000, 89: 1122-1128. 10.1080/713794561.CrossRef
19.
go back to reference Wamani H, Astrøm AN, Peterson S, Tumwine JK, Tylleskär T: Predictors of poor anthropometric status among children under 2 years of age in rural Uganda. Public Health Nutr. 2006, 9: 320-326. 10.1079/PHN2006854.CrossRefPubMed Wamani H, Astrøm AN, Peterson S, Tumwine JK, Tylleskär T: Predictors of poor anthropometric status among children under 2 years of age in rural Uganda. Public Health Nutr. 2006, 9: 320-326. 10.1079/PHN2006854.CrossRefPubMed
20.
go back to reference Black RE, Brown KH, Becker S, Alim AR, Huq I: Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh. II. Incidence of diarrhea and association with known pathogens. Am J Epidemiol. 1982, 115: 315-324.PubMed Black RE, Brown KH, Becker S, Alim AR, Huq I: Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh. II. Incidence of diarrhea and association with known pathogens. Am J Epidemiol. 1982, 115: 315-324.PubMed
21.
go back to reference Checkley W, Gilman RH, Black RE, et al: Effects of nutritional status on diarrhea in Peruvian children. J Pediatr. 2002, 140: 210-218. 10.1067/mpd.2002.121820.CrossRefPubMed Checkley W, Gilman RH, Black RE, et al: Effects of nutritional status on diarrhea in Peruvian children. J Pediatr. 2002, 140: 210-218. 10.1067/mpd.2002.121820.CrossRefPubMed
22.
go back to reference Lee G, Cama V, Gilman RH, et al: Comparison of two types of epidemiological surveys aimed at collecting daily clinical symptoms in community-based longitudinal studies. Ann Epidemiol. 2010, 20: 151-158. 10.1016/j.annepidem.2009.10.004.CrossRefPubMedPubMedCentral Lee G, Cama V, Gilman RH, et al: Comparison of two types of epidemiological surveys aimed at collecting daily clinical symptoms in community-based longitudinal studies. Ann Epidemiol. 2010, 20: 151-158. 10.1016/j.annepidem.2009.10.004.CrossRefPubMedPubMedCentral
23.
go back to reference Madhi SA, Cunliffe NA, Steele D, et al: Effect of human rotavirus vaccine on severe diarrhea in African infants. NEJM. 2010, 362: 289-298. 10.1056/NEJMoa0904797.CrossRefPubMed Madhi SA, Cunliffe NA, Steele D, et al: Effect of human rotavirus vaccine on severe diarrhea in African infants. NEJM. 2010, 362: 289-298. 10.1056/NEJMoa0904797.CrossRefPubMed
24.
go back to reference Young B, Briscoe J: A case-control study of the effect of environmental sanitation on diarrhoea morbidity in Malawi. J Epidemiol Community Health. 1988, 42: 83-88. 10.1136/jech.42.1.83.CrossRefPubMedPubMedCentral Young B, Briscoe J: A case-control study of the effect of environmental sanitation on diarrhoea morbidity in Malawi. J Epidemiol Community Health. 1988, 42: 83-88. 10.1136/jech.42.1.83.CrossRefPubMedPubMedCentral
25.
go back to reference Peterson EA, Roberts L, Toole MJ, Peterson DE: The effect of soap distribution on diarrhoea: Nyamithuthu Refugee Camp. Int J Epidemiol. 1988, 27: 520-524. 10.1093/ije/27.3.520.CrossRef Peterson EA, Roberts L, Toole MJ, Peterson DE: The effect of soap distribution on diarrhoea: Nyamithuthu Refugee Camp. Int J Epidemiol. 1988, 27: 520-524. 10.1093/ije/27.3.520.CrossRef
26.
go back to reference World Health Organization: The analytic review of the Integrated Management of Childhood Illness strategy. 2003, Geneva World Health Organization: The analytic review of the Integrated Management of Childhood Illness strategy. 2003, Geneva
Metadata
Title
The duration of diarrhea and fever is associated with growth faltering in rural Malawian children aged 6-18 months
Authors
Ariana Weisz
Gus Meuli
Chrissie Thakwalakwa
Indi Trehan
Kenneth Maleta
Mark Manary
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Nutrition Journal / Issue 1/2011
Electronic ISSN: 1475-2891
DOI
https://doi.org/10.1186/1475-2891-10-25

Other articles of this Issue 1/2011

Nutrition Journal 1/2011 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine