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Published in: Journal of Gastrointestinal Surgery 10/2018

01-10-2018 | Original Article

The Cost of Failure: Assessing the Cost-Effectiveness of Rescuing Patients from Major Complications After Liver Resection Using the National Inpatient Sample

Authors: Jay J. Idrees, Charles W. Kimbrough, Brad F. Rosinski, Carl Schmidt, Mary E. Dillhoff, Eliza W. Beal, Fabio Bagante, Katiuscha Merath, Qinyu Chen, Jordan M. Cloyd, E. Christopher Ellison, Timothy M. Pawlik

Published in: Journal of Gastrointestinal Surgery | Issue 10/2018

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Abstract

Objective

To estimate the cost of rescue and cost of failure and determine cost-effectiveness of rescue from major complications at high-volume (HV) and low-volume (LV) centers

Methods

Ninety-six thousand one hundred seven patients undergoing liver resection were identified from the Nationwide Inpatient Sample (NIS) between 2002 and 2011. The incremental cost of rescue and cost of FTR were calculated. Using propensity-matched cohorts, a cost-effectiveness analysis was performed to determine the incremental cost-effectiveness ratio (ICER) between HV and LV hospitals.

Results

Ninety-six thousand one hundred seven patients were identified in NIS. The overall mortality was 2.3% and was lowest in HV centers (HV 1.4% vs. MV 2.1% vs. LV 2.6%; p < 0.001). Major complications occurred in 14.9% of hepatectomies and were comparable regardless of volume (HV 14.2% vs. MV 14.3% vs. LV 15.4%; p < 0.001). The FTR rate was substantially lower among HV centers (HV 7.7%, MV 11%, LV 12%; p < 0.001). At a willingness to pay benchmark of $50,000 per year of life saved, both HV (ICER = $3296) and MV (ICER = $4182) centers were cost-effective at rescuing patients from a major complication compared to LV hospitals.

Conclusion

Not only was FTR less common at HV hospitals, but the management of most major complications was cost-effective at higher volume centers.
Literature
1.
go back to reference Vonlanthen R, Slankamenac K, Breitenstein S, et al. The impact of complications on costs of major surgical procedures: a cost analysis of 1200 patients. Ann Surg 2011; 254(6):907–13.CrossRefPubMed Vonlanthen R, Slankamenac K, Breitenstein S, et al. The impact of complications on costs of major surgical procedures: a cost analysis of 1200 patients. Ann Surg 2011; 254(6):907–13.CrossRefPubMed
2.
go back to reference Nelson-Williams H, Gani F, Kilic A, et al. Factors Associated With Interhospital Variability in Inpatient Costs of Liver and Pancreatic Resections. JAMA Surg 2016; 151(2):155–63.CrossRefPubMed Nelson-Williams H, Gani F, Kilic A, et al. Factors Associated With Interhospital Variability in Inpatient Costs of Liver and Pancreatic Resections. JAMA Surg 2016; 151(2):155–63.CrossRefPubMed
3.
go back to reference Gani F, Pawlik TM. Assessing the Costs Associated with Volume-Based Referral for Hepatic Surgery. J Gastrointest Surg 2016; 20(5):945–52.CrossRefPubMed Gani F, Pawlik TM. Assessing the Costs Associated with Volume-Based Referral for Hepatic Surgery. J Gastrointest Surg 2016; 20(5):945–52.CrossRefPubMed
4.
go back to reference Ghaferi AA, Birkmeyer JD, Dimick JB. Complications, failure to rescue, and mortality with major inpatient surgery in medicare patients. Ann Surg 2009; 250(6):1029–34.CrossRefPubMed Ghaferi AA, Birkmeyer JD, Dimick JB. Complications, failure to rescue, and mortality with major inpatient surgery in medicare patients. Ann Surg 2009; 250(6):1029–34.CrossRefPubMed
5.
go back to reference Ghaferi AA, Dimick JB. Variation in mortality after high-risk cancer surgery: failure to rescue. Surg Oncol Clin N Am 2012; 21(3):389–95, vii.CrossRefPubMed Ghaferi AA, Dimick JB. Variation in mortality after high-risk cancer surgery: failure to rescue. Surg Oncol Clin N Am 2012; 21(3):389–95, vii.CrossRefPubMed
6.
go back to reference Spolverato G, Ejaz A, Hyder O, Kim Y, Pawlik TM. Failure to rescue as a source of variation in hospital mortality after hepatic surgery. Br J Surg 2014; 101(7):836–46.CrossRefPubMed Spolverato G, Ejaz A, Hyder O, Kim Y, Pawlik TM. Failure to rescue as a source of variation in hospital mortality after hepatic surgery. Br J Surg 2014; 101(7):836–46.CrossRefPubMed
7.
go back to reference Silber JH, Williams SV, Krakauer H, et al. Hospital and patient characteristics associated with death after surgery. A study of adverse occurrence and failure to rescue. Med Care 1992; 30(7):615–29.CrossRefPubMed Silber JH, Williams SV, Krakauer H, et al. Hospital and patient characteristics associated with death after surgery. A study of adverse occurrence and failure to rescue. Med Care 1992; 30(7):615–29.CrossRefPubMed
8.
go back to reference Cutler DM, Scott Morton F. Hospitals, market share, and consolidation. Jama 2013; 310(18):1964–70.CrossRefPubMed Cutler DM, Scott Morton F. Hospitals, market share, and consolidation. Jama 2013; 310(18):1964–70.CrossRefPubMed
9.
go back to reference Cerullo M, Chen SY, Dillhoff M, et al. Association of Hospital Market Concentration With Costs of Complex Hepatopancreaticobiliary Surgery. JAMA Surg 2017; 152(9):e172158.CrossRefPubMedPubMedCentral Cerullo M, Chen SY, Dillhoff M, et al. Association of Hospital Market Concentration With Costs of Complex Hepatopancreaticobiliary Surgery. JAMA Surg 2017; 152(9):e172158.CrossRefPubMedPubMedCentral
10.
go back to reference Wright JD, Tergas AI, Hou JY, et al. Effect of Regional Hospital Competition and Hospital Financial Status on the Use of Robotic-Assisted Surgery. JAMA Surg 2016; 151(7):612–20.CrossRefPubMed Wright JD, Tergas AI, Hou JY, et al. Effect of Regional Hospital Competition and Hospital Financial Status on the Use of Robotic-Assisted Surgery. JAMA Surg 2016; 151(7):612–20.CrossRefPubMed
11.
go back to reference Xu T, Wu AW, Makary MA. The Potential Hazards of Hospital Consolidation: Implications for Quality, Access, and Price. Jama 2015; 314(13):1337–8.CrossRefPubMed Xu T, Wu AW, Makary MA. The Potential Hazards of Hospital Consolidation: Implications for Quality, Access, and Price. Jama 2015; 314(13):1337–8.CrossRefPubMed
13.
go back to reference Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40(5):373–83.CrossRefPubMed Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40(5):373–83.CrossRefPubMed
14.
go back to reference Quan H, Parsons GA, Ghali WA. Validity of information on comorbidity derived rom ICD-9-CCM administrative data. Med Care 2002; 40(8):675–85.CrossRefPubMed Quan H, Parsons GA, Ghali WA. Validity of information on comorbidity derived rom ICD-9-CCM administrative data. Med Care 2002; 40(8):675–85.CrossRefPubMed
15.
go back to reference Iezzoni LI, Daley J, Heeren T, et al. Identifying complications of care using administrative data. Med Care 1994; 32(7):700–15.CrossRefPubMed Iezzoni LI, Daley J, Heeren T, et al. Identifying complications of care using administrative data. Med Care 1994; 32(7):700–15.CrossRefPubMed
16.
go back to reference Weingart SN, Iezzoni LI, Davis RB, et al. Use of administrative data to find substandard care: validation of the complications screening program. Med Care 2000; 38(8):796–806.CrossRefPubMed Weingart SN, Iezzoni LI, Davis RB, et al. Use of administrative data to find substandard care: validation of the complications screening program. Med Care 2000; 38(8):796–806.CrossRefPubMed
17.
go back to reference Cillo U, Spolverato G, Vitale A, et al. Liver Resection for Advanced Intrahepatic Cholangiocarcinoma: A Cost-Utility Analysis. World J Surg 2015; 39(10):2500–9.CrossRefPubMed Cillo U, Spolverato G, Vitale A, et al. Liver Resection for Advanced Intrahepatic Cholangiocarcinoma: A Cost-Utility Analysis. World J Surg 2015; 39(10):2500–9.CrossRefPubMed
18.
go back to reference Grosse SD. Assessing cost-effectiveness in healthcare: history of the $50,000 per QALY threshold. Expert Rev Pharmacoecon Outcomes Res 2008; 8(2):165–78.CrossRefPubMed Grosse SD. Assessing cost-effectiveness in healthcare: history of the $50,000 per QALY threshold. Expert Rev Pharmacoecon Outcomes Res 2008; 8(2):165–78.CrossRefPubMed
19.
go back to reference Stain SC, Hoyt DB, Hunter JG, et al. American surgery and the Affordable Care Act. JAMA Surg 2014; 149(9):984–5.CrossRefPubMed Stain SC, Hoyt DB, Hunter JG, et al. American surgery and the Affordable Care Act. JAMA Surg 2014; 149(9):984–5.CrossRefPubMed
20.
go back to reference Gani F, Hundt J, Daniel M, et al. Variations in hospitals costs for surgical procedures: inefficient care or sick patients? Am J Surg 2017; 213(1):1–9.CrossRefPubMed Gani F, Hundt J, Daniel M, et al. Variations in hospitals costs for surgical procedures: inefficient care or sick patients? Am J Surg 2017; 213(1):1–9.CrossRefPubMed
21.
go back to reference Dimick JB, Chen SL, Taheri PA, et al. Hospital costs associated with surgical complications: a report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg 2004; 199(4):531–7.CrossRefPubMed Dimick JB, Chen SL, Taheri PA, et al. Hospital costs associated with surgical complications: a report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg 2004; 199(4):531–7.CrossRefPubMed
22.
go back to reference Friese CR, Lake ET, Aiken LH, et al. Hospital nurse practice environments and outcomes for surgical oncology patients. Health Serv Res 2008; 43(4):1145–63.CrossRefPubMedPubMedCentral Friese CR, Lake ET, Aiken LH, et al. Hospital nurse practice environments and outcomes for surgical oncology patients. Health Serv Res 2008; 43(4):1145–63.CrossRefPubMedPubMedCentral
23.
go back to reference Page AJ, Gani F, Crowley KT, et al. Patient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection. Br J Surg 2016; 103(5):564–71.CrossRefPubMed Page AJ, Gani F, Crowley KT, et al. Patient outcomes and provider perceptions following implementation of a standardized perioperative care pathway for open liver resection. Br J Surg 2016; 103(5):564–71.CrossRefPubMed
24.
go back to reference Haut ER, Pronovost PJ, Schneider EB. Limitations of administrative databases. Jama, Vol. 307. United States; 2012:pp. 2589; author reply 2589-90. Haut ER, Pronovost PJ, Schneider EB. Limitations of administrative databases. Jama, Vol. 307. United States; 2012:pp. 2589; author reply 2589-90.
25.
go back to reference Sarrazin MS, Rosenthal GE. Finding pure and simple truths with administrative data. Jama, Vol. 307. United States; 2012:pp. 1433–5. Sarrazin MS, Rosenthal GE. Finding pure and simple truths with administrative data. Jama, Vol. 307. United States; 2012:pp. 1433–5.
Metadata
Title
The Cost of Failure: Assessing the Cost-Effectiveness of Rescuing Patients from Major Complications After Liver Resection Using the National Inpatient Sample
Authors
Jay J. Idrees
Charles W. Kimbrough
Brad F. Rosinski
Carl Schmidt
Mary E. Dillhoff
Eliza W. Beal
Fabio Bagante
Katiuscha Merath
Qinyu Chen
Jordan M. Cloyd
E. Christopher Ellison
Timothy M. Pawlik
Publication date
01-10-2018
Publisher
Springer US
Published in
Journal of Gastrointestinal Surgery / Issue 10/2018
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-018-3826-6

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