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European Journal of Medical Research

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Open Access 01-12-2014 | Research

The correlation between the expression of differentiated embryo-chondrocyte expressed gene l and oral squamous cell carcinoma

Authors: Jingmin You, Lu Lin, Qiong Liu, Tengfei Zhu, Kun Xia, Tong Su

Published in: European Journal of Medical Research | Issue 1/2014

Abstract

Background

This study aims to explore the correlation between expression of differentiated embryo-chondrocyte expressed gene l (DEC1) and oral squamous cell carcinoma (OSCC), which could provide the reference for treatment and prognosis assessment of OSCC.

Methods

The expression of DEC1 in tissues from 56 primary OSCC patients and 20 normal oral mucosa samples were detected using real-time polymerase chain reaction and immunohistochemical methods, respectively.

Results

The results showed that the positive expression rate of DEC1 in the OSCC group was significantly higher than that in the normal group (P <0.05); further, the expression of DEC1 in different OSCC groups was statistically significant (P <0.05). The expression of DEC1 in the 1-year recurrence OSCC group was significantly higher than other groups. The expression of DEC1 in the 3-years no recurrence OSCC group was the lowest.

Conclusions

The expression of DEC1 was associated with the incidence of OSCC and there was a negative correlation between the expression of DEC1 and the prognosis of OSCC.

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Title: The correlation between the expression of differentiated embryo-chondrocyte expressed gene l and oral squamous cell carcinoma
Authors: Jingmin You
Lu Lin
Qiong Liu
Tengfei Zhu
Kun Xia
Tong Su
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: European Journal of Medical Research / Issue 1/2014
Electronic ISSN: 2047-783X
DOI: https://doi.org/10.1186/2047-783X-19-21

At a glance: The STEP trials

Springer Medicine

The correlation between the expression of differentiated embryo-chondrocyte expressed gene l and oral squamous cell carcinoma

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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